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Oestrogen and progesterone receptors in acoustic neuroma

Published online by Cambridge University Press:  29 June 2007

J. W. A. Curley*
Affiliation:
The Department of Otolaryngology and Neurosurgery, The Christie Hospital and Holt Radium Institute, Wilmslow Road, Manchester M20 9BX.
R. T. Ramsden
Affiliation:
The Department of Otolaryngology and Neurosurgery, The Christie Hospital and Holt Radium Institute, Wilmslow Road, Manchester M20 9BX.
A. Howell
Affiliation:
The Department of Otolaryngology Manchester Royal Infirmary, Oxford Road, Manchester M139WL. The Christie Hospital and Holt Radium Institute, Wilmslow Road, Manchester M20 9BX.
K. Healy
Affiliation:
The Department of Otolaryngology Manchester Royal Infirmary, Oxford Road, Manchester M139WL. The Christie Hospital and Holt Radium Institute, Wilmslow Road, Manchester M20 9BX.
R. H. Lye
Affiliation:
The Department of Otolaryngology the Clinical Research Department, The Christie Hospital and Holt Radium Institute, Wilmslow Road, Manchester M20 9BX.
*
Mrs J Curley, Northwood, White Coppice, Angleyorke, Lanes PR6 9DF

Abstract

Tissue samples from fourteen consecutive (8 male: 6 female) acoustic neuromas were assayed for hormone receptors using either a monoclonal antibody (MA), dextran coated charcoal (DCC) or isoelectric focusing (IEF) technique.

In this series there were no unequivocally positive results, a finding at variance with previously published results.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1990

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References

Barnes, D. M., Ribeiro, G. G., Skinner, L. G. (1977) Two methods for measurement of oestradiol-17 and progesterone receptors in human breast cancer and correlation with response to treatment. European Journal of Cancer, 13: 11331143.Google Scholar
Cushing, H. (1917) Tumours of the nervus acusticus and the syndrome of the cerebellopontile angle. WB Saunders, Philadelphia, London. p 296.Google Scholar
Donnell, M. S., Meyer, G. A., Donegan, W. L. (1979) Estrogen receptor protein in intracranial meningiomas. Journal of Neurosurgery, 50: 499502.Google Scholar
Dutton, J. E. M., Ramsden, R. T., Lye, R. H., Morris, K., Keith, A. O., Page, R., Vafadis, J. (1990) Acoustic neuroma surgery—1978–1990. Journal of Laryngology and Otology, in press.Google Scholar
Greene, G. L., Nolan, C., Engler, J. P., Jensen, E. V. (1980) Monoclonal antibodies to human estrogen receptor. Proceedings of the National Academy of Science USA, 77: 51155119.Google Scholar
Harland, R. N. L., Hayward, E., Barnes, D. M. (1983) Progesterone receptor measurement by isoelectric focusing: a potential microassay. Clinica Chimica Acta, 133: 159168.CrossRefGoogle ScholarPubMed
House, W. F. (1968) (ed): Acoustic Neuroma. Monograph II. Archives of Otolaryngology, 88: 576715.CrossRefGoogle Scholar
Kasantikul, V., Netsky, M. G., Glasscock, M. E., Hays, J. W. (1980) Acoustic neurilemmoma: clinicoanatomical study of 103 patients. Journal of Neurosurgery, 52: 2835.Google Scholar
Kasantikul, V., Brown, W. J. (1981) Estrogen receptors in acoustic neurilemmomas. Surgical Neurology, 15: 105109.Google Scholar
Lye, R. H., Elstow, S. F., Weiss, J. B. (1986) Neovascularization of intracranial tumours. In: Biology of Brain Tumours, (Walker, M. D., Thomas, D. G. T., eds) 8: 6166. Nijhoff Martinus, Boston.Google Scholar
Markwalder, T. M., Zava, D. T., Goldhirsch, A., Markwalder, R. V. (1983) Estrogen and progesterone receptors in meningiomas in relation to clinical and pathologic features. Surgical Neurology, 20: 4247.Google Scholar
Markwalder, T. M., Markwalder, R. V., Zava, D. T. (1984) Estrogen and progestin receptors in meningiomas: clinicopathological correlations. Clinical Neuropharmacology, 7: 368374.Google Scholar
Markwalder, T. M., Waelti, E., Markwalder, R. V. (1986) Estrogen and progestin receptors in acoustic and spinal neurilemmomas. Surgical Neurology, 26: 142148.Google Scholar
Martuza, R. L., MacLaughlin, D. T., Ojeman, R. G. (1981) Specific estradiol binding in schwannomas, meningiomas and neurofibromas. Neurosurgery, 9: 665670.Google Scholar
Martuza, R. L., Miller, D. C., MacLaughlin, D. T. (1985) Estrogen and progestin binding by cytosolic and nuclear fractions of human meningiomas. Journal of Neurosurgery, 62: 750756.Google Scholar
Perrot-Applanat, M., Logeat, F., Groyer-Picard, M. T., Milgrom, E. (1985) Immunocytochemical study of mammalian progesterone receptor using monoclonal antibodies. Endocrinology, 116: 14731484.Google Scholar
Scatchard, G. (1949) The attraction of proteins for small ions andmolecules. Annals of the New York Academy of Science, 51: 660672.Google Scholar
Wiet, R. J., Young, N. M., Monsell, E. M., O'Connor, C. A., Kazan, R. (1989) Age considerations in acoustic neuroma surgery: the horns of a dilemma. American Journal of Otology, 10: 177180.Google Scholar