Hostname: page-component-586b7cd67f-rcrh6 Total loading time: 0 Render date: 2024-11-20T06:31:01.618Z Has data issue: false hasContentIssue false
  • English
  • Français

Nasal T-cell lymphoma associated with Epstein-Barr virus infection

Published online by Cambridge University Press:  29 June 2007

J. Dhaliwal ,
D. C. Rowlands ,
G. Niedobitek ,
A. Williams ,
A. Das Gupta  and
E. L. Jones
J. Dhaliwal
Affiliation:
Department of Ear, Nose and Throat Surgery, Queen Elizabeth Hospital, Birmingham.
D. C. Rowlands*
Affiliation:
Departments of Pathology, The Medical School, University of Birmingham, Birmingham, UK.
G. Niedobitek
Affiliation:
Departments of Pathology, The Medical School, University of Birmingham, Birmingham, UK.
A. Williams
Affiliation:
Departments of Pathology, The Medical School, University of Birmingham, Birmingham, UK.
A. Das Gupta
Affiliation:
Department of Ear, Nose and Throat Surgery, Queen Elizabeth Hospital, Birmingham.
E. L. Jones
Affiliation:
Departments of Pathology, The Medical School, University of Birmingham, Birmingham, UK.
*
Dr D. C. Rowlands, M.R.C.Path., Department of Pathology, The Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT.
Get access Rights & Permissions [Opens in a new window]

Abstract

A case of nasal T-cell lymphoma in a Caucasian male is reported, in which the presence of Epstein-Barr virus within tumour cells was demonstrated by in situ hybridization to the Epstein-Barr virus encoded RNAs EBER-1 and EBER-2.

Keywords

Epstein-Barr virusLymphomaT-cellNose
Type
Pathology in Focus
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 5 , May 1993 , pp. 468 - 470
Copyright
Copyright © JLO (1984) Limited 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Harabuchi, Y., Yamanaka, N., Kataura, A., Imai, S., Kinoshita, T., Mizuno, E., Osata, T. (1990) Epstein-Barr virus in nasal T-cell lymphomas in patients with lethal midline granuloma. Lancet 335: 128–130CrossRefGoogle ScholarPubMed
Ho, F. C. S., Srivastava, G., Loke, S. L., Fu, K. H., Leung, B. P. Y., Liang, R., Choy, D. (1990) Presence of Epstein-Barr virus DNA in nasal lymphomas of B and T-cell type. Hematological Oncology 8: 271–281CrossRefGoogle ScholarPubMed
Katzenstein, A. A., Peiper, S. C. (1990) Detection of Epstein-Barr virus genomes in lymphomatoid granulomatosis: analysis of 29 cases by the polymerase chain reaction technique. Modern Pathology 3: 435–441Google ScholarPubMed
Medeiros, L. J., Jaffe, E. S., Chen, Y. Y, Weiss, L. M. (1992) Local ization of Epstein-Barr viral genomes in angiocentric imraunoproliferative lesions. American Journal of Surgical Pathology 16: 439–447CrossRefGoogle Scholar
Michaels, L. (1989) Head and neck tumours. In Recent Advances in Histopathology. Vol. 14. (Anthony, P. P., MacSween, R. N. M., eds.), Churchill-Livingstone, London, pp 97–122.Google Scholar
Niedobitek, G., Young, L. S., Sam, C. K., Brooks, C. K., Prasad, U., Rickinson, A. B. (1992) Expression of Epstein-Barr virus genes and of lymphocyte activation molecules in undifferentiated nasopharyngeal carcinomas. American Journal of Pathology 140: 879–887Google ScholarPubMed
Vilde, J. L., Perronne, C., Huchon, A., Leport, C., Gehanno, P., Marche, C., de The, G. (1985) Association of Epstein-Barr virus with lethal midline granuloma. New England Journal of Medicine 313: 1161.Google ScholarPubMed