Hostname: page-component-586b7cd67f-2brh9 Total loading time: 0 Render date: 2024-11-30T03:04:51.382Z Has data issue: false hasContentIssue false

Multiple synchronous carcinoma of the aero-digestive tract

Published online by Cambridge University Press:  29 June 2007

Andrew McCombe
Affiliation:
Senior House Officer and
Valerie J. Lund*
Affiliation:
Senior Lecturer, Professorial Unit, Institute of Laryngology and Otology, Gray's Inn Road, London WC1X 8DA
David J. Howard
Affiliation:
Senior Lecturer, Professorial Unit, Institute of Laryngology and Otology, Gray's Inn Road, London WC1X 8DA
*
Valerie J. Lund, M.S., F.R.C.S., Professional Unit, Institute of Laryngology and Otology, Gray's Inn Road, London WCIX 8DA.

Abstract

Multiple carcinoma of the upper aerodigestive tract is an increasingly recognized problem, and a concept of ‘field cancerization’ has been proposed to explain this phenomena. The initial assessment of a patient with an isolated aerodigestive carcinoma must be extensive so as not to miss any synchronous lesions, and may include radiography and endoscopy. Treatment cannot be standardised but must be tailored to suit individual problems and because of the high incidence of metachronous tumours, follow-up must be both thorough and ‘lifelong’.

A case of three primary synchronous squamous carcinomas of the upper aerodigestive tract is presented. The relevant literature is reviewed.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bilroth, T. (1882) Die Allegemeine chirurgishe pathologie und theraie in 51 vorlesungen: Ein Handbuch fur Studirende und Aertze. G. Reimer: Berlin p. 980.Google Scholar
Gluckman, J. L. (1979) Synchronous multiple primary lesions of the upper aerodigestive system. Archives of Otolaryngology, 105: 597598.CrossRefGoogle ScholarPubMed
Gluckman, J. L. and Crissman, J. D. (1983) Survival rates in 548 patients with multiple neoplasms of the upper aerodigestive tract. Laryngoscope, 93: 7174.CrossRefGoogle ScholarPubMed
Gluckman, J. L.Crissman, J. D. and Donegan, J. D. (1980) Multicentric squamous cell carcinoma of the upper aerodigestive tract. Head and Neck Surgery, 3: 9096.CrossRefGoogle ScholarPubMed
Kogelnik, H. D.Fletcher, G. H. and Jesse, R. J. (1975) Clinical course of patients with squamous cell carcinoma of the upper respiratory and digestive tracts with no evidence of digestive five years after initial treatment. Radiology, 115: 423427.CrossRefGoogle ScholarPubMed
McCollough, W. M.Million, R. R.Parsons, J. T.Mendenhall, W. M. and Cassis, N. J.(1988) Treatment results for simultaneous primary squamous cell carcinomas of the head and neck. Laryngoscope, 98: 7982.CrossRefGoogle ScholarPubMed
Michaels, L. (1987) Ear, nose and throat histopathology. 1st Edition, Springer Verlag. London p. 380385.CrossRefGoogle Scholar
Parker, J. T. and Hill, J. H. (1988) Panendoscopy in screening for synchronous primary malignancies. Laryngoscope, 98: 147149.CrossRefGoogle ScholarPubMed
Shibuya, H.Amagasa, T.Hanai, A.Horiuchi, J. and Suzuki, S. (1986) Second primary carcinomas in patients with squamous cell carcinoma of the maxillary sinus. Cancer, 50: 11221125.3.0.CO;2-4>CrossRefGoogle Scholar
Slaughter, D. P.Southwick, H. W. and Smejkal, W. (1953) ‘Field cancerization’ in oral stratified squamousepithelium. Cancer, 6: 963968.3.0.CO;2-Q>CrossRefGoogle Scholar
Vrabec, D. P. (1979) Multiple primary malignancies of the upper aerodigestive tract. Annals of Otology, Rhinology and Laryngology, 85: 846854.CrossRefGoogle Scholar
Warren, S. and Gates, E. (1932)Multiple primary malignant tumours: A survey of the literature and statistical study. American Journal of Cancer 51: 13581403.Google Scholar
Weichart, K. A. and Schumrich, D. (1979) Multiple malignancies in patients with primary carcinomas of the head and neck. Laryngoscope, 89: 988991.CrossRefGoogle Scholar