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Metronidazole ototoxicity - report of two cases

Published online by Cambridge University Press:  29 June 2007

S. M. Iqbal ,
J. G. Murthy ,
P. K. Banerjee  and
K. A. Vishwanathan
S. M. Iqbal*
Affiliation:
Department of Otorhinolaryngology, JLN Hospital and Research Centre, Bhilai Steel Plant, Bhilai, India.
J. G. Murthy
Affiliation:
Department of Otorhinolaryngology, JLN Hospital and Research Centre, Bhilai Steel Plant, Bhilai, India.
P. K. Banerjee
Affiliation:
Department of Otorhinolaryngology, JLN Hospital and Research Centre, Bhilai Steel Plant, Bhilai, India.
K. A. Vishwanathan
Affiliation:
Department of Otorhinolaryngology, JLN Hospital and Research Centre, Bhilai Steel Plant, Bhilai, India.
*
Address for correspondence: Dr S. M. Iqbal, Joint Director and Head, Department of Otorhinolaryngology, JLN Hospital and Research Centre, Bhilai (MP), India490 009.
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Abstract

Two cases of bilateral moderate to severe sensorineural hearing loss due to oral administration of metronidazole are reported. There has been only one case report of deafness following metronidazole therapy in the world literature. The hearing loss recovered gradually in a period of four to six weeks following withdrawal of drug and oral steroid therapy. The possible mechanism of ototoxicity is discussed. Awareness by the treating physician of ototoxicity due to any drug is stressed.

Keywords

Hearing loss, sensorineuralMetronidasoleDrug toxicity
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 113 , Issue 4 , April 1999 , pp. 355 - 357
Copyright
Copyright © JLO (1984) Limited 1999

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References

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