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Malignant fibrous histiocytoma of maxilla following radiotherapy for bilateral retinoblastoma

Published online by Cambridge University Press:  29 June 2007

S. Nishizawa ,
T. Hayashida ,
S. Horiguchi ,
K. Inouye  and
T. Imamura
S. Nishizawa*
Affiliation:
Department of Otorhinolaryngology, National Defense Medical College.
T. Hayashida
Affiliation:
Department of Otohinolaryngology, Faculty of Medicine, University of Tokyo.
S. Horiguchi
Affiliation:
Department of Otohinolaryngology, Faculty of Medicine, University of Tokyo.
K. Inouye
Affiliation:
Department of Otohinolaryngology, Faculty of Medicine, University of Tokyo.
T. Imamura
Affiliation:
Department of Pathology, Branch Hospital, University of Tokyo.
*
Dr. Shinji Nishizawa, M.D., Department of Otorhinolarybgology, National Defense Medica; College, 3–2, Namiki, Tokorozawa, 359, Japan.
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Abstract

A 20-year-old man developed a malignant fibrous histiocytoma in the right maxilla 19 years after irradiation for bilateral retinoblastoma.

The incidence of second tumours in patients who survived bilateral retinoblastoma treated with radiation was 8.5 per cent. Malignant fibrous histiocytomas which arise in a site of prior radiation are fatal. The present case is presumed to have the autosomal dominant retinoblastoma gene, not associated with deletion of the q 14 band of chromosome 13. The patient succumbed to the second tumour.

Type
Clinical records
Information
The Journal of Laryngology & Otology , Volume 99 , Issue 5 , May 1985 , pp. 501 - 504
Copyright
Copyright © JLO (1984) Limited 1985

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References

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