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Magnetic resonance non-echo planar diffusion-weighted imaging accuracy in detecting cholesteatoma in comparison with clinical and surgical findings

Part of: JLO Editors' Choice Papers 2022

Published online by Cambridge University Press:  18 August 2021

N Al Zuhir ,
I Zammit-Maempel ,
P Yates  and
J Dixon
N Al Zuhir*
Affiliation:
Department of Radiology, Newcastle upon Tyne Hospitals, Newcastle upon Tyne, UK
I Zammit-Maempel
Affiliation:
Department of Radiology, Newcastle upon Tyne Hospitals, Newcastle upon Tyne, UK
P Yates
Affiliation:
Department of ENT, Newcastle upon Tyne Hospitals, Newcastle upon Tyne, UK
J Dixon
Affiliation:
Department of Radiology, Newcastle upon Tyne Hospitals, Newcastle upon Tyne, UK
*
Author for correspondence: Dr Naail Al Zuhir, Department of Radiology, Freeman Hospital, Freeman Road, Newcastle upon TyneNE7 7DN, UK E-mail: [email protected]
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Abstract

Objective

Magnetic resonance imaging utilising non-echo planar diffusion-weighted imaging is known to have high sensitivity and specificity in detecting cholesteatoma.

Method

Data was retrospectively collected from patients who had undergone non-echo planar diffusion-weighted imaging from 1 January 2010 to 31 December 2016. The ratio of average pixel grey-scale values between the middle-ear lesion, pons and temporal lobe was used to quantify the degree of restricted diffusion and assess the statistical significance to detect cholesteatoma.

Results

A total of 107 patients had non-echo planar diffusion-weighted imaging during the study period. Non-echo planar diffusion-weighted imaging shows good specificity and sensitivity with an excellent positive predictive value and accuracy. Analysis of the grey-scale pixel ratio for cholesteatoma detection showed statistically significant results.

Conclusion

Non-echo planar diffusion-weighted magnetic resonance imaging is accurate for cholesteatoma assessment. When the middle-ear lesion non-echo planar diffusion-weighted imaging intensity is higher than the ipsilateral temporal lobe, it is highly suggestive of a cholesteatoma formation.

Keywords

CholesteatomaDiagnosisMagnetic Resonance ImagingDiffusion Magnetic Resonance Imaging
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 136 , Issue 3 , March 2022 , pp. 208 - 214
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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Footnotes

Dr N Al Zuhir takes responsibility for the integrity of the content of the paper

Presented as a poster at the British Society of Head and Neck Imaging: Head and Neck Imaging Refresher Course, 9 February 2018, Newcastle upon Tyne, UK.

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