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Laryngeal sensory neuropathy in patients with diabetes mellitus

Published online by Cambridge University Press:  22 July 2014

A L Hamdan ,
A Dowli ,
R Barazi ,
J Jabbour  and
S Azar
A L Hamdan
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, American University of Beirut Medical Center, New York, USA
A Dowli
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, American University of Beirut Medical Center, New York, USA
R Barazi
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, American University of Beirut Medical Center, New York, USA
J Jabbour
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, American University of Beirut Medical Center, New York, USA
S Azar*
Affiliation:
Internal Medicine Department, American University of Beirut Medical Center, New York, USA
*
Address for correspondence: Dr S Azar, Department of Internal Medicine, American University of Beirut, 3 Dag Hammarskjold Plaza, 8th Floor, NY 10017, USA Fax: +00 (0)961 1 350000 E-mail: [email protected]
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Abstract

Objective:

To determine the prevalence of laryngeal sensory neuropathy in patients with type 2 diabetes mellitus.

Methods:

A cross-sectional study was performed, comprising 50 patients diagnosed with type 2 diabetes mellitus and 36 healthy controls. In the diabetic group, glycaemic control level, disease duration and presence of neuropathy were assessed. Participants were diagnosed with laryngeal sensory neuropathy if they had a cough, globus pharyngeus or throat clearing lasting for more than six weeks, in the absence of laryngopharyngeal reflux disease, allergies, asthma, angiotensin-converting enzyme inhibitor intake or psychogenic disorders.

Results:

In the diabetic group, the mean age ± standard deviation was 44.66 ± 10.07 years. Sixty per cent of patients were male, 42 per cent had had diabetes for more than five years and 52 per cent had average to poor glycaemic control. The prevalence of laryngeal sensory neuropathy was 42 per cent in the diabetic group, compared with 13.9 per cent in controls; this difference was statistically significant (p = 0.005). There was no association between the prevalence of laryngeal sensory neuropathy and glycaemic control level, disease duration or presence of neuropathy.

Conclusion:

Laryngeal sensory neuropathy is more common in patients with type 2 diabetes mellitus than in controls.

Keywords

Diabetes Mellitus, Type 2CoughPharyngeal DiseasesLaryngeal Nerves
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 128 , Issue 8 , August 2014 , pp. 725 - 729
Copyright
Copyright © JLO (1984) Limited 2014 

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