Hostname: page-component-586b7cd67f-t8hqh Total loading time: 0 Render date: 2024-11-22T23:48:33.507Z Has data issue: false hasContentIssue false
  • English
  • Français

Laryngeal candidiasis: A cause of airway obstruction in the immunocompromised child

Published online by Cambridge University Press:  29 June 2007

Edward W. Fisher ,
Aurelia Richards ,
Glenn Anderson  and
David M. Albert
Edward W. Fisher*
Affiliation:
Department of Paediatric Otolaryngology, at the Hospitals for Sick Children, Great Ormond Street, London.
Aurelia Richards
Affiliation:
Department of Paediatric Otolaryngology, at the Hospitals for Sick Children, Great Ormond Street, London.
Glenn Anderson
Affiliation:
Department of Histopathology at the Hospitals for Sick Children, Great Ormond Street, London.
David M. Albert
Affiliation:
Department of Paediatric Otolaryngology, at the Hospitals for Sick Children, Great Ormond Street, London.
*
Mr E. W. Fisher, Senior Registrar in Otolaryngology, The Royal National Throat, Nose and Ear Hospital, Grays Inn Road, London WC1X 8DA.
Get access Rights & Permissions [Opens in a new window]

Abstract

Laryngeal involvement with Candida is usually secondary to pulmonary candidiasis and is seen in patients with impaired immunity. We report a case of isolated laryngeal candidiasis involving the vestibular folds and presenting with stridor in a one-year-old child with Down's syndrome and hypogammaglobulinaemia. Vestibular fold reduction and fluconazole achieved resolution of the disease. Candidiasis should be considered in any potentially immunodeficient child presenting with symptoms of laryngeal disease.

Keywords

CandidaLarynxDown's syndromeAirway obstructionImmunocompetence
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 2 , February 1992 , pp. 168 - 170
Copyright
Copyright © JLO (1984) Limited 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Babu, S., Samuel, P. (1988) The effect of inhaled steroids on the upper respiratory tract. Journal of Laryngology and Otology, 102: 592–594.CrossRefGoogle ScholarPubMed
Bailey, C. M., Croft, C. B. (1987) Stertor, sleep apnoea and velopharyngeal insufficiency. In Scott-Brown's Otolaryngology, 5th edn., Vol. 6, Paediatric Otolaryngology, (Evans, J. N. G., and Kerr, A. G.) Butterworths: London, p. 350–367.Google Scholar
Bye, R. R., Palomba, A., Bernstein, L., Shah, K. (1987) Clinical Candida supraglottitis in an infant with AIDS-related complex. Pediatric Pulmonology, 3: 280–281.CrossRefGoogle Scholar
Cinnamond, M. J. (1987) Stridor. In Scott-Brown's Otolaryngology, 5th edn., Vol. 6. Paediatric Otolaryngology (Evans, J. N. G., and Kerr, A. G., eds.) London: Butterworths. p. 420–427.Google Scholar
Cole, S., Zawin, M., Lundberg, B., Hoffmann, J., Bailey, L., Ernstoff, M. S. (1987) Candida epiglottitis in an adult with acute nonlymphocytic leukaemia. American Journal of Medicine, 82: 662–664.CrossRefGoogle Scholar
Epstein, J. B., Truelove, E. L., Izutzu, K. T. (1984) Oral candidias: pathogenesis and host defense. Review of Infectious Diseases, 6: 96–106.CrossRefGoogle Scholar
Friedmann, I., Ferlito, A. (1988) Granulomas and neoplasms of the larynx. Churchill Livingstone: Edinburgh, p. 49–59.Google Scholar
Gorlin, R. J., Cohen, M. M., Levin, L. S. (1990) Chromosomal syndromes: common and/or well known syndromes. In: Syndromes of the head and neck, 3rd edn., Oxford University Press: New York. p. 33–40.Google Scholar
Hass, A., Hyatt, A. C, Kattan, M., Weiner, M. A., Hodes, D. S. (1987) Hoarseness in immunocompromised children: association with invasive fungal infection. Journal of Pediatrics, 111: 731–733.CrossRefGoogle ScholarPubMed
Jacobs, R. F., Yasuda, K., Smith, A., Benjamin, D. R. (1982) Laryngeal candidiasis presenting as inspiratory stridor. Pediatrics, 69: 234–236.CrossRefGoogle ScholarPubMed
Kobayashi, R., Rosenblatt, H. M., Carney, J. M, Byrne, W. J., Ament, M. E., Mendoza, G. R., Dudley, J. P., Stiehm, E. R. (1980) Candida esophagitis and laryngitis in chronic mucocutaneous candidiasis. Pediatrics, 66: 380–384.CrossRefGoogle ScholarPubMed
Lyons, G. D. (1966) Mycotic disease of the larynx. Annals of Otology, Rhinology, and Laryngology, 75: 162–175.CrossRefGoogle ScholarPubMed
Michaels, L. (1984) Pathology of the larynx. Springer-Veriag: Berlin p. 95–97.CrossRefGoogle Scholar
Miller, R., Gray, S. D., Cotton, R. T., Myer, C. M. III, Netteville, J. Subglottic stenosis and Down's syndrome. (1990) American Journal of Otolaryngology, 11: 274–277.CrossRefGoogle Scholar
Murphy, J. E, Jones, M., Thompson, E. N. (1984) Oesophageal candidiasis and croup in a child with defective neutrophil motility. Journal of Infection, 8: 247–250.CrossRefGoogle Scholar
Ochs, H. D., Wedgwood, R. J. (1989) Disorders of the B cell system. In: Immunologic disorders in infants and children, 3rd edn.,(Stiehm, E. R., ed.) W. B. Saunders: Philadelphia, p. 246–247.Google Scholar
Perrone, J. A. (1970) Laryngeal obstruction due to monilia albicans in a newborn. Laryngoscope, 80: 288–291.CrossRefGoogle ScholarPubMed
Shearer, W. T., Anderson, D. C. (1989) The secondary immune deficiencies. In: Immunologic disorders in infants and children, 3rd Edition (Steihm, E. R. edn.), W. B. Saunders: Philadelphia. p. 400–401.Google Scholar
Tashjian, L. S., Peacock, J. E. (1984) Laryngeal candidiasis. Archives of Otolaryngology, 110: 806–809.CrossRefGoogle ScholarPubMed
Tedeschi, L. G., Cheren, R. V. (1968) Laryngeal hyperkeratosis due to primary monilial infection. Archives of Otolaryngology, 87: 100–102.Google Scholar
Walsh, T. J., Gray, W. C. (1987) Candida epiglottis in immunocompromised patients. Chest, 91: 482–485.CrossRefGoogle Scholar
Williams, M. A. (1987) Head and neck findings in paediatric acquired immune deficiency syndrome. Laryngoscope, 97: 713–716.CrossRefGoogle ScholarPubMed
Yonkers, A. J. (1973) Candidiasis of the larynx. Annals of Otology, Rhinology and Laryngology, 82: 812–815.Google Scholar