Hostname: page-component-586b7cd67f-l7hp2 Total loading time: 0 Render date: 2024-11-26T17:28:01.102Z Has data issue: false hasContentIssue false
  • English
  • Français

Kaposi's sarcoma of the head and neck in patients with AIDS

Published online by Cambridge University Press:  29 June 2007

N. D. Stafford ,
R. C. D. Herdman ,
S. Forster  and
A. J. Munrot
N. D. Stafford*
Affiliation:
Departments of ENT Surgery, St. Mary's Hospital, Praed Street, London.
R. C. D. Herdman
Affiliation:
Departments of ENT Surgery, St. Mary's Hospital, Praed Street, London.
S. Forster
Affiliation:
Department of Genito-Urinary Medicine, St. Mary's Hospital, Praed Street, London.
A. J. Munrot
Affiliation:
Department of Radiotherapyt, St. Mary's Hospital, Praed Street, London.
*
Mr. N. D. Stafford F.R.C.S., ENT Department, St. Mary's Hospital, Praed Street, London W2 1NY.
Get access Rights & Permissions [Opens in a new window]

Abstract

Over a 40 month period, 219 patients with AIDS were seen at St. Mary's Hospital, London. Kaposi's sarcoma, one of the criteria for diagnosing the syndrome, was the presenting feature in 62 patients. Eighty four patients developed Kaposi's sarcoma at some stage of their disease and the head and neck region was involved in 56 of them.

Although Kaposi's sarcoma is rarely life threatening in AIDS, potential airway obstruction, pain or cosmetic disfigurement may justify treating the lesion. Whilst cutaneous tumours may be managed by using radiotherapy (16 Gray in four fractions over four days), this treatment produces a sever mucositis when used to treat mucosal disease; we, therefore use a combination of vincristine and bleomycin for this.

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 103 , Issue 4 , April 1989 , pp. 379 - 382
Copyright
Copyright © JLO (1984) Limited 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Biggar, R. J. (1986) The AIDS problem in Africa. Lancet, 79–83.CrossRefGoogle ScholarPubMed
Centers for Disease Control. (1983) Update AIDS. Morbidity and Mortality Weekly Report, 32: 389–391.Google Scholar
Centers for Disease Control (1986). Classification system for human T-lymphotrophic virus type 3/lymphadenopathy-associated virus infections. Morbidity and Mortality Weekly Report, 35:334–339.Google Scholar
Francis, N. D., Parkin, J. M., Weber, J. and Boylston, A. W. (1986) Kaposi's sarcoma in acquired immune deficiency syndrome (AIDS). Journal of Clinical Pathology, 39: 469–474.CrossRefGoogle ScholarPubMed
Friedman-Klein, A. E., Laubenstein, L. J. and Marmor, M. (1981) Kaposi's sarcoma and pneumocystis pneumonia in New York and San Francisco. Morbidity and Mortality Weekly Report, 30: 305–308.Google Scholar
Gnepp, D. R., Chandler, W. and Hyams, V. (1984) Primary Kaposi's sarcoma in the head and neck. Annals of Internal Medicine, 100: 107–114.CrossRefGoogle ScholarPubMed
Hymes, K., Cheung, T., Greene, J. B., Prose, N. S., Marcus, S., Ballard, H., William, D. C. and Laubenstein, L. J. (1981) Kaposi's sarcoma in homosexual men. A report of eight cases. Lancet, 2: 598–600.CrossRefGoogle ScholarPubMed
Kaposi, M. (1872) Idiopathisehes multiplespigmensarkom der haut. Archives of Dermatology and Syphilology, 4: 265–273.CrossRefGoogle Scholar
Levy, E.M., Beldekas, J.C., Black, P.H., Lerman, R. H., Cottrell, M. C. and Kushi, L. H. (1985) Patients with Kaposi sarcoma who opt for no treatment. Lancet, 2: 223.CrossRefGoogle ScholarPubMed
Moskowitz, L., Hensley, G. T., Chan, J. C. and Adams, K. (1985) Immediate causes of death in acquired immunodeficiency syndrome. Archives of Pathology and Laboratory Medicine, 109: 735–738.Google ScholarPubMed
Pinching, A. J. (1986) AIDS and Africa: lessons for us all. Journal of the Royal Society of Medicine, 79: 501–503.CrossRefGoogle Scholar
Rose, H. S., Balthazar, E. J., Megibow, A. J., Horowitz, L. and Laubenstein, L. J. (1982) Alimentary tract involvement in Kaposi sarcoma: radiographic and endoscopic findings in 25 homosexual men. American Journal of Radiology, 139: 661–666.Google ScholarPubMed
Safai, B., Johnson, K. G., Myskowski, P. L., Koziner, B., Yang, S. Y., Cunningham-Rundles, S., Godbold, J. H. and Dupont, B. (1985) The natural history of Kaposi's sarcoma in the acquired immunodeficiency syndrome. Annals of Internal Medicine, 103: 744–750.CrossRefGoogle ScholarPubMed
Urmacher, C., Myskowski, P. L., Ochoa, M., Kris, M. and Safai, B. (1982) Outbreak of Kaposi's sarcoma with cytomegalovirus infection in young homosexual men. American Journal of Medicine, 72: 569–575.CrossRefGoogle ScholarPubMed
Weber, J. (1984) Is AIDS an epidemic form of African Kaposi's sarcoma? Discussion paper. Journal of the Royal Society of Medicine, 77: 572–576.CrossRefGoogle ScholarPubMed