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Intraluminal three-dimensional optical coherence tomography – a tool for imaging of the Eustachian tube?

Published online by Cambridge University Press:  18 February 2019

R Schuon ,
B Mrevlje ,
B Vollmar ,
T Lenarz  and
G Paasche
R Schuon*
Affiliation:
Department of Otorhinolaryngology, Hannover Medical School, Germany
B Mrevlje
Affiliation:
Trent Cardiac Centre, Nottingham University Hospital NHS Trust, UK
B Vollmar
Affiliation:
Rudolf-Zenker-Institute for Experimental Surgery, Rostock Medical School, Germany
T Lenarz
Affiliation:
Department of Otorhinolaryngology, Hannover Medical School, Germany Hearing4all Cluster of Excellence, Hannover Medical School, Germany
G Paasche
Affiliation:
Department of Otorhinolaryngology, Hannover Medical School, Germany Hearing4all Cluster of Excellence, Hannover Medical School, Germany
*
Author for correspondence: Dr Robert Schuon, Department of Otorhinolaryngology, Hannover Medical School, Germany E-mail: [email protected]
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Abstract

Objectives

The cause of Eustachian tube dysfunction often remains unclear. Therefore, this study aimed to examine the feasibility and possible diagnostic use of optical coherence tomography in the Eustachian tube ex vivo.

Methods

Two female blackface sheep cadaver heads were examined bilaterally. Three conditions of the Eustachian tube were investigated: closed (resting position), actively opened and stented. The findings were compared (and correlated) with segmented histological cross-sections.

Results

Intraluminal placement of the Eustachian tube with the optical coherence tomography catheter was performed without difficulty. Regarding the limited infiltration depth of optical coherence tomography, tissues can be differentiated. The localisation of the stent was accurate as was the lumen.

Conclusion

The application of optical coherence tomography in the Eustachian tube under these experimental conditions is considered to be a feasible, rapid and non-invasive diagnostic method, with possible diagnostic value for determining the luminal shape and superficial lining tissue of the Eustachian tube.

Keywords

Eustachian TubeTomography, Optical CoherenceMiddle Ear VentilationImaging, Three Dimensional
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 133 , Issue 2 , February 2019 , pp. 87 - 94
Copyright
Copyright © JLO (1984) Limited, 2019 

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Footnotes

Dr R Schuon takes responsibility for the integrity of the content of the paper

References

1Takasaki, K, Takahashi, H, Miyamoto, I, Yoshida, H, Yamamoto-Fukuda, T, Enatsu, K et al. Measurement of angle and length of the eustachian tube on computed tomography using the multiplanar reconstruction technique. Laryngoscope 2007;117:1251–4Google Scholar
2Yeh, AT, Kao, B, Jung, WG, Chen, Z, Nelson, JS, Tromberg, BJ. Imaging wound healing using optical coherence tomography and multiphoton microscopy in an in vitro skin-equivalent tissue model. J Biomed Opt 2004;9:248–53Google Scholar
3Aloisi, A, Sonoda, Y, Gardner, GJ, Park, KJ, Elliott, SL, Zhou, QC et al. Prospective comparative study of laparoscopic narrow band imaging (NBI) versus standard imaging in gynecologic oncology. Ann Surg Oncol 2018;25:984–90Google Scholar
4Di Martino, E, Walther, LE, Maneschi, P, Westhofen, M. Endoscopic examinations of the eustachian tube [in German]. HNO 2006;54:85–92Google Scholar
5Poe, DS, Pyykko, I, Valtonen, H, Silvola, J. Analysis of eustachian tube function by video endoscopy. Am J Otol 2000;21:602–7Google Scholar
6Poe, DS, Abou-Halawa, A, Abdel-Razek, O. Analysis of the dysfunctional eustachian tube by video endoscopy. Otol Neurotol 2001;22:590–5Google Scholar
7Songu, M, Aslan, A, Unlu, HH, Celik, O. Neural control of eustachian tube function. Laryngoscope 2009;119:1198–202Google Scholar
8Di Martino, EF. Eustachian tube function tests: an update [in German]. HNO 2013;61:467–76Google Scholar
9Vignali, L, Solinas, E, Emanuele, E. Research and clinical applications of optical coherence tomography in invasive cardiology: a review. Curr Cardiol Rev 2014;10:369–76Google Scholar
10Kranjec, I, Mrevlje, B, Legutko, J, Dudek, D. Optical coherence tomography: guided primary percutaneous coronary intervention in acute myocardial infarction. A bridge too far? Kardiol Pol 2015;73:309–16Google Scholar
11Roleder, T, Jakala, J, Kaluza, GL, Partyka, L, Proniewska, K, Pociask, E et al. The basics of intravascular optical coherence tomography. Postepy Kardiol Interwencyjnej 2015;11:74–83Google Scholar
12Kardon, RH. Role of the macular optical coherence tomography scan in neuro-ophthalmology. J Neuroophthalmol 2011;31:353–61Google Scholar
13Hanna, N, Saltzman, D, Mukai, D, Chen, Z, Sasse, S, Milliken, J et al. Two-dimensional and 3-dimensional optical coherence tomographic imaging of the airway, lung, and pleura. J Thorac Cardiovasc Surg 2005;129:615–22Google Scholar
14Volgger, V, Arens, C, Kraft, M, Englhard, AS, Betz, CS. Optical coherence tomography for early diagnosis of epithelial dysplasia and microinvasive carcinoma of the upper aerodigestive tract [in German]. HNO 2016;64:34–40Google Scholar
15Jungheim, M, Donner, S, Bleeker, S, Ripken, T, Krueger, A, Ptok, M. Effect of saline inhalation on vocal fold epithelial morphology evaluated by optical coherence tomography. Laryngoscope 2016;126:E332–6Google Scholar
16Kobler, JB, Chang, EW, Zeitels, SM, Yun, SH. Dynamic imaging of vocal fold oscillation with four-dimensional optical coherence tomography. Laryngoscope 2010;120:1354–62Google Scholar
17Cho, NH, Lee, SH, Jung, W, Jang, JH, Kim, J. Optical coherence tomography for the diagnosis and evaluation of human otitis media. J Korean Med Sci 2015;30:328–35Google Scholar
18Mrevlje, B, Legutko, J, Jakala, J, Noc, M, Dudek, D, Birkemeyer, R et al. Optical coherence tomography of coronary arteries--a novel intravascular imaging modality [in German]. Dtsch Med Wochenschr 2014;139:1941–6Google Scholar
19Schroder, S, Lehmann, M, Ebmeyer, J, Upile, T, Sudhoff, H. Balloon Eustachian tuboplasty: a retrospective cohort study. Clin Otolaryngol 2015;40:629–38Google Scholar
20Pohl, F, Schuon, RA, Miller, F, Kampmann, A, Bultmann, E, Hartmann, C et al. Stenting the Eustachian tube to treat chronic otitis media - a feasibility study in sheep. Head Face Med 2018;14:8Google Scholar
21Tearney, GJ, Regar, E, Akasaka, T, Adriaenssens, T, Barlis, P, Bezerra, HG et al. Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation. J Am Coll Cardiol 2012;59:1058–72Google Scholar
22Prati, F, Guagliumi, G, Mintz, GS, Costa, M, Regar, E, Akasaka, T et al. Expert review document part 2: methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures. Eur Heart J 2012;33:2513–20Google Scholar
23Lee, TM, Oldenburg, AL, Sitafalwalla, S, Marks, DL, Luo, W, Toublan, FJ et al. Engineered microsphere contrast agents for optical coherence tomography. Opt Lett 2003;28:1546–8Google Scholar
24Nayak, AR, Shajahan, TK, Panfilov, AV, Pandit, R. Spiral-wave dynamics in a mathematical model of human ventricular tissue with myocytes and fibroblasts. PLoS One 2013;8:e72950Google Scholar