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The interface of paediatric ENT and autism spectrum disorder: a complex conundrum for otolaryngologists

Published online by Cambridge University Press:  08 September 2022

S Gimlette  and
E Stapleton Open the ORCID record for E Stapleton [Opens in a new window]
S Gimlette
Affiliation:
University of Manchester Medical School, Manchester, UK
E Stapleton*
Affiliation:
Department of Otolaryngology, Manchester Royal Infirmary, UK
*
Author for correspondence: Miss Emma Stapleton, Department of Otolaryngology, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK E-mail: [email protected]
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Abstract

Objective

Autism spectrum disorder is a lifelong neurodevelopmental condition encompassing complex physical and neurological symptoms, including complex sensory symptoms. This review explores the interface between autism spectrum disorder and paediatric ENT.

Methods

Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (‘PRISMA’) guideline, a robust literature search and review was conducted by two researchers. Thirty-four papers were filtered into the final review.

Results

Published literature clearly demonstrates potential for autism spectrum disorder to present in the form of auditory and other sensory symptoms to ENT surgeons and audiologists who may not fully appreciate this complex condition. Despite this well-documented link, auditory symptoms, auditory processing disorders and hearing loss within autism spectrum disorder remain poorly understood.

Conclusion

Improved recognition and understanding of autism spectrum disorder by otolaryngologists could enable more effective diagnostic and management strategies for autistic children who present with auditory and other sensory symptoms. In light of the current ‘autism epidemic,’ there is an urgent need for further research on this theme.

Keywords

Autistic DisorderAudiologyOtolaryngology
Type
Review Article
Information
The Journal of Laryngology & Otology , Volume 137 , Issue 10 , October 2023 , pp. 1083 - 1089
Copyright
Copyright © The Author(s), 2022. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

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Footnotes

Dr E Stapleton takes responsibility for the integrity of the content of the paper

References

Biyani, S, Morgan, PS, Hotchkiss, K, Cecchini, M, Derkay, CS. Autism spectrum disorder 101: a primer for pediatric otolaryngologists. Int J Pediatr Otorhinolaryngol 2015;79:798–802CrossRefGoogle ScholarPubMed
Fahy, R, Corbett, M, Keogh, I. Improving peri-operative psychosocial interventions for children with autism spectrum disorder undergoing ENT procedures. J Laryngol Otol 2020;134:838–44CrossRefGoogle Scholar
Mathew, R, Bryan, J, Chaudhry, D, Chaudhry, A, Kuhn, I, Tysome, J et al. Cochlear implantation in children with autism spectrum disorder: a systematic review and pooled analysis. Otol Neurotol 2022;43:e1–13CrossRefGoogle ScholarPubMed
Hitoglou, M, Ververi, A, Antoniadis, A, Zafeiriou, DI. Childhood autism and auditory system abnormalities. Pediatr Neurol 2009;42:309–14CrossRefGoogle Scholar
Meinzen-Derr, J, Wiley, S, Bishop, S, Manning-Courtney, P, Choo, DI, Murray, D. Autism spectrum disorders in 24 children who are deaf or hard of hearing. Int J Pediatr Otorhinolaryngol 2014;78:112–18CrossRefGoogle ScholarPubMed
Ishtiaq, N, Mumtaz, N, Saqulain, G. Stress and coping strategies for parenting children with hearing impairment and autism. Pakistan J Med Sci 2020;36:538–43Google ScholarPubMed
Klin, A. Auditory brainstem responses in autism: brainstem dysfunction or peripheral hearing loss? J Autism Dev Disord 1993;23:15–35CrossRefGoogle ScholarPubMed
Rimland, B, Edelson, SM. Brief report: a pilot study of auditory integration training in autism. J Autism Dev Disord 1995;25:61–70CrossRefGoogle ScholarPubMed
Williams, ZJ, Abdelmessih, PG, Key, AP, Woynaroski, TG. Cortical auditory processing of simple stimuli is altered in autism: a meta-analysis of auditory evoked responses. Biol Psychiatry Cogn Neurosci Neuroimaging 2021;6:767–81Google ScholarPubMed
Danesh, AA, Howery, S, Aazh, H, Kaf, W, Eshraghi, AA. Hyperacusis in autism spectrum disorders. Audiol Res 2021;11:547–56CrossRefGoogle ScholarPubMed
Rosenhall, U, Nordin, V, Sandström, M, Ahlsén, G, Gillberg, C. Autism and hearing loss. J Autism Dev Disord 1999;29:349–57CrossRefGoogle ScholarPubMed
Benich, S, Thakur, S, Schubart, JR, Carr, MM. Parental perception of the perioperative experience for children with autism. AORN J 2018;108:34–43CrossRefGoogle ScholarPubMed
Lord, C, Elsabbagh, M, Baird, G, Veenstra-Vanderweele, J. Autism spectrum disorder. Lancet 2018;392:508–20CrossRefGoogle ScholarPubMed
National Institute of Mental Health. Autism Spectrum Disorder. In: https://www.nimh.nih.gov/health/topics/autism-spectrum-disorders-asd [26 May 2022]Google Scholar
Moore, DR. Editorial: Auditory processing disorder. Ear Hear 2018;39:617–20CrossRefGoogle ScholarPubMed
Takahashi, H, Mori, H, Kitahara, K, Kita, M, Nakai, Y. Hyperacusis. Pract Otol 2022;73:145–54CrossRefGoogle Scholar
Noreña, AJ, Lacher-Fougère, S, Fraysse, MJ, Bizaguet, E, Grevin, P, Thai-Van, H et al. A contribution to the debate on tinnitus definition. Prog Brain Res 2021;262:469–85CrossRefGoogle Scholar
Miyagishima, R, Hopper, T, Hodgetts, B, Soos, B, Williamson, T, Drummond, N. Development of a case definition for hearing loss in community-based older adults: a cross-sectional validation study. CMAJ Open 2021;9:E796–801CrossRefGoogle ScholarPubMed
Berman, JI, Chudnovskaya, D, Blaskey, L, Kuschner, E, Mukherjee, P, Buckner, R et al. Relationship between M100 auditory evoked response and auditory radiation microstructure in 16p11.2 deletion and duplication carriers. Am J Neuroradiol 2016;37:1178–84CrossRefGoogle ScholarPubMed
Arksey, H, O'Malley, L. Scoping studies: towards a methodological framework. Int J Soc Res Methodol 2005;8:19–32CrossRefGoogle Scholar
Masi, A, DeMayo, MM, Glozier, N, Guastella, AJ. An overview of autism spectrum disorder, heterogeneity and treatment options. Neurosci Bull 2017;33:183–93CrossRefGoogle ScholarPubMed
National Institute for Health and Care Excellence. Autism Spectrum Disorder in Adults: Diagnosis and Management. London: National Institute for Health and Care Excellence, 2021Google Scholar
Law, JK, Rubenstein, E, Marvin, AR, Toroney, J, Lipkin, PH. Auditory Sensitivity Issues in Children with Autism Spectrum Disorders: Characteristics and Burden. Presented at Pediatric Academic Societies Meeting, 30 April – 3 May 2016, Baltimore, MD, USA. In: https://iancommunity.org/sites/default/files/galleries/conference-presentations/Law_PAS_2016.pdf [20 January 2023]Google Scholar
Bennetto, L, Keith, JM, Allen, PD, Luebke, AE. Children with autism spectrum disorder have reduced otoacoustic emissions at the 1 kHz mid-frequency region. Autism Res 2017;10:337–45CrossRefGoogle ScholarPubMed
Williams, ZJ, Suzman, E, Woynaroski, TG. Prevalence of decreased sound tolerance (hyperacusis) in individuals with autism spectrum disorder: a meta-analysis. Ear Hear 2021;42:1137–50CrossRefGoogle ScholarPubMed
Wilson, US, Sadler, KM, Hancock, KE, Guinan, JJ, Lichtenhan, JT. Efferent inhibition strength is a physiological correlate of hyperacusis in children with autism spectrum disorder. J Neurophysiol 2017;118:1164–72CrossRefGoogle ScholarPubMed
Williams, ZJ, He, JL, Cascio, CJ, Woynaroski, TG. A review of decreased sound tolerance in autism: definitions, phenomenology, and potential mechanisms. Neurosci Biobehav Rev 2021;121:1–17CrossRefGoogle ScholarPubMed
Myne, S, Kennedy, V. Hyperacusis in children: a clinical profile. Int J Pediatr Otorhinolaryngol 2018;107:80–5CrossRefGoogle ScholarPubMed
Scheerer, NE, Boucher, TQ, Bahmei, B, Iarocci, G, Arzanpour, S, Birmingham, E. Family experiences of decreased sound tolerance in ASD. J Autism Dev Disord 2021;52:4007–21CrossRefGoogle ScholarPubMed
Esmaili, AA, Renton, J. A review of tinnitus. Aust J Gen Pract 2018;47:205–8CrossRefGoogle ScholarPubMed
Danesh, AA, Lang, D, Kaf, W, Andreassen, WD, Scott, J, Eshraghi, AA. Tinnitus and hyperacusis in autism spectrum disorders with emphasis on high functioning individuals diagnosed with Asperger's syndrome. Int J Pediatr Otorhinolaryngol 2015;79:1683–8CrossRefGoogle ScholarPubMed
O'Connor, K. Auditory processing in autism spectrum disorder: a review. Neurosci Biobehav Rev 2012;36:836–54CrossRefGoogle ScholarPubMed
Bouvet, L, Simard-Meilleur, AA, Paignon, A, Mottron, L, Donnadieu, S. Auditory local bias and reduced global interference in autism. Cognition 2014;131:367–72CrossRefGoogle ScholarPubMed
Remington, A, Fairnie, J. A sound advantage: increased auditory capacity in autism. Cognition 2017;166:459–65CrossRefGoogle ScholarPubMed
Alcántara, JI, Weisblatt, EJL, Moore, BCJ, Bolton, PF. Speech-in-noise perception in high-functioning individuals with autism or Asperger's syndrome. J Child Psychol Psychiatry 2004;45:1107–14CrossRefGoogle ScholarPubMed
Port, RG, Edgar, JC, Ku, M, Bloy, L, Murray, R, Blaskey, L et al. Maturation of auditory neural processes in autism spectrum disorder — a longitudinal MEG study. NeuroImage Clin 2016;11:566–77CrossRefGoogle ScholarPubMed
Matsuzaki, J, Ku, M, Berman, JI, Blaskey, L, Bloy, L, Chen, YH et al. Abnormal auditory mismatch fields in adults with autism spectrum disorder. Neurosci Lett 2019;698:140–5CrossRefGoogle ScholarPubMed
Mandell, DS, Novak, MM, Zubritsky, CD. Factors associated with age of diagnosis among children with autism spectrum disorders. Pediatrics 2005;116:1480–6CrossRefGoogle ScholarPubMed
Gillberg, C, Ehlers, S, Schaumann, H, Jakobsson, G, Dahlgren, SO, Lindblom, R et al. Autism under age 3 years: a clinical study of 28 cases referred for autistic symptoms in infancy. J Child Psychol Psychiatry 1990;31:921–34CrossRefGoogle Scholar
Schwemmle, C, Schwemmle, U, Ptok, M. Autistic communication disorders [in German]. HNO 2008;56:169–76CrossRefGoogle Scholar
Valero, MR, Sadadcharam, M, Henderson, L, Freeman, SR, Lloyd, S, Green, KM et al. Compliance with cochlear implantation in children subsequently diagnosed with autism spectrum disorder. Cochlear Implants Int 2016;17:200–6CrossRefGoogle ScholarPubMed
ICD-11 for Mortality and Morbidity Statistics 2022. In: https://icd.who.int/browse11 [19 January 2023]Google Scholar