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Incidence of meningitis secondary to suppurative otitis media in adults

Published online by Cambridge University Press:  05 May 2010

S I Ibrahim ,
P P Cheang  and
D A Nunez
S I Ibrahim
Affiliation:
Department of Otolaryngology, National University Hospital, Singapore
P P Cheang
Affiliation:
Department of ENT, Birmingham Children's Hospital NHS Foundation Trust, Bristol, UK
D A Nunez*
Affiliation:
Academic Department of Otolaryngology, ENT Unit, Southmead Hospital, Bristol, UK
*
Address for correspondence: Mr D A Nunez, Academic Department of Otolaryngology, ENT Unit, Southmead Hospital, North Bristol NHS Trust, Bristol BS10 5NB, UK. Fax: +44 (0)117 959 5850 E-mail: [email protected]
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Abstract

Aim:

Meningitis is the commonest intracranial complication of suppurative otitis media, and carries the risk of death and life-changing morbidity. This study aimed to estimate the risk of an adult in the UK developing otogenic meningitis.

Methods:

Adults hospitalised with meningitis in Bristol from 1997 to 2002 were identified retrospectively. Cases confirmed by positive blood culture or cerebrospinal fluid investigation were studied. A case was classified as otogenic if there was coexistent evidence of ear infection.

Results:

Eighty-seven cases of meningitis were analysed. The overall mortality rate was 5.7 per cent. Acute and chronic suppurative otitis media accounted for 13 and three cases, respectively. The adult population of Bristol at the midpoint of the study was 635 976.

Conclusion:

In this study, the age-adjusted incidence of otogenic meningitis was 0.42 per 100 000 per year.

Keywords

Otitis Media, SuppurativeComplicationsIncidenceAdultMeningitis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 124 , Issue 11 , November 2010 , pp. 1158 - 1161
Copyright
Copyright © JLO (1984) Limited 2010

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Footnotes

Presented in part at the Southwestern Laryngological Association Meeting, 16 November 2007, Bristol, UK.

References

1 Browning, GG, Gatehouse, S. The prevalence of middle ear disease in the adult British population. Clin Otolaryngol Allied Sci 1992;17:317–21CrossRefGoogle ScholarPubMed
2 Ram, B, Meiklejohn, DJ, Nunez, DA, Murray, A, Watson, HG. Combined risk factors contributing to cerebral venous thrombosis in a young woman. J Laryngol Otol 2001;115:307–10CrossRefGoogle ScholarPubMed
3 Leskinen, K, Jero, J. Acute complications of otitis media in adults. Clin Otolaryngol 2005;30:511–16CrossRefGoogle ScholarPubMed
4 Nunez, DA, Browning, GG. Risks of developing an otogenic intracranial abscess. J Laryngol Otol 1990;104:468–72CrossRefGoogle ScholarPubMed
5 In International Statistical Classification of Diseases and Related Health Problems 10th Revision, Version for 2003, Chapter VI G00-G99 Diseases of the nervous system http://apps.who.int/classifications/apps/icd/icd10online2003/fr-icd.htm [8 April 2010]Google Scholar
6 Publication Hub – Gateway to UK National Statistics. In: http://www.statistics.gov.uk [28 October 2008]Google Scholar
7 Is Your Answer Correct? In: http://www.causascientia.org/math_stat/ProportionCI.html [9 January 2010]Google Scholar
8 Kim, CS, Jung, HW, Yoo, KY. Prevalence of otitis media and allied diseases in Korea – results of a nation-wide survey, 1991. J Korean Med Sci 1993;8:34–40CrossRefGoogle ScholarPubMed
9 Rantakallio, P, Leskinen, M, von Wendt, L. Incidence and prognosis of central nervous system infections in a birth cohort of 12,000 children. Scand J Infect Dis 1986;18:287–94CrossRefGoogle Scholar
10 Kupila, L, Vuorinen, T, Vainionpaa, R, Hukkanen, V, Marttila, RJ, Kotilainen, P. Etiology of aseptic meningitis and encephalitis in an adult population. Neurology 2006;66:75–80CrossRefGoogle Scholar
11 Brivet, FG, Ducuing, S, Jacobs, F, Chary, I, Pompier, R, Prat, D et al. Accuracy of clinical presentation for differentiating bacterial from viral meningitis in adults: a multivariate approach. Intensive Care Med 2005;31:1654–60CrossRefGoogle ScholarPubMed
12 Steele, RW, Marmer, DJ, O'Brien, MD, Tyson, ST, Steele, CR. Leukocyte survival in cerebrospinal fluid. J Clin Microbiol 1986;23:965–6CrossRefGoogle ScholarPubMed
13 Lindquist, L, Linne, T, Hansson, LO, Kalin, M, Axelsson, G. Value of cerebrospinal fluid analysis in the differential diagnosis of meningitis: a study in 710 patients with suspected central nervous system infection. Eur J Clin Microbiol Infect Dis 1988;7:374–80CrossRefGoogle ScholarPubMed
14 Hosoglu, S, Ayaz, C, Geyik, MF, Kokoglu, OF, Ozen, A. Acute bacterial meningitis in adults: analysis of 218 episodes. Ir J Med Sci 1997;166:231–4CrossRefGoogle ScholarPubMed
15 Barry, B, Delattre, J, Vie, F, Bedos, JP, Gehanno, P. Otogenic intracranial infections in adults. Laryngoscope 1999;109:483–7CrossRefGoogle ScholarPubMed
16 Geyik, MF, Kokoglu, OF, Hosoglu, S, Ayaz, C. Acute bacterial meningitis as a complication of otitis media and related mortality factors. Yonsei Med J 2002;43:573–8CrossRefGoogle ScholarPubMed
17 Penido Nde, O, Borin, A, Iha, LC, Suguri, VM, Onishi, E, Fukuda, Y et al. Intracranial complications of otitis media: 15 years of experience in 33 patients. Otolaryngol Head Neck Surg 2005;132:37–42CrossRefGoogle ScholarPubMed
18 Habib, RG, Girgis, NI, Abu el Ella, AH, Farid, Z, Woody, J. The treatment and outcome of intracranial infections of otogenic origin. J Trop Med Hyg 1988;91:83–6Google ScholarPubMed
19 Fernandez Rodriguez, R, Porto Golpe, I, Santos Perez, S, Labella Caballero, T. Intracranial complications of otitis: the present-day situation [in Spanish]. An Otorrinolaringol Ibero Am 1989;16:281–97Google ScholarPubMed
20 Gower, D, McGuirt, WF. Intracranial complications of acute and chronic infectious ear disease: a problem still with us. Laryngoscope 1983;93:1028–33CrossRefGoogle ScholarPubMed
21 Migirov, L, Duvdevani, S, Kronenberg, J. Otogenic intracranial complications: a review of 28 cases. Acta Otolaryngol 2005;125:819–22CrossRefGoogle ScholarPubMed
22 Tandon, S, Beasley, N, Swift, AC. Changing trends in intracranial abscesses secondary to ear and sinus disease. J Laryngol Otol 2009;123:283–8CrossRefGoogle ScholarPubMed