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Immunopathology of polymorphic reticulosis of the larynx

Published online by Cambridge University Press:  29 June 2007

Tadashi Nakashima*
Affiliation:
Department of Otolaryngology, National Kyushu Cancer Center
Mayumi Inamitsu
Affiliation:
Department of Otolaryngology, Kyushu University School of Medicine, Fukuoka 815, Japan.
Takuya Uemura
Affiliation:
Department of Otolaryngology, Kyushu University School of Medicine, Fukuoka 815, Japan.
Takuya Sugimoto
Affiliation:
Department of Pathology, Kyushu University School of Medicine, Fukuoka 815, Japan.
*
Tadashi Nakashima, MD, Department of Otolaryngology, National Kyushu Cancer Center, Notame 3-1-1, Minami-ku, Fukuoka 815, Japan.

Abstract

We treated a 28-year-old woman with initial symptoms of hoarseness. At biopsy, atypical lymphoid cells infiltrate was observed in the submucosa of the larynx and polymorphic reticulosis was diagnosed. Immunohistochemical examination of the laryngeal material obtained at autopsy revealed a strong reaction of lymphoid cells to the monoclonal antibody to human T lymphocytes. The possibility that polymorphic reticulosis is a transitional form of peripheral T cell lymphoma was confirmed.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1989

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