Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-23T14:10:26.774Z Has data issue: false hasContentIssue false
  • English
  • Français

Hypersensitivity to topical corticosteroids in otitis externa

Published online by Cambridge University Press:  29 June 2007

S. M. Wilkinson  and
M. H. Beck
S. M. Wilkinson*
Affiliation:
Salford
M. H. Beck
Affiliation:
Salford
*
Dr S. M. Wilkinson, The Skin Hospital, Chapel Street, Salford M60 9EP.
Get access Rights & Permissions [Opens in a new window]

Abstract

Over a12-monthperiod, nine patients were seen in a contact dermatitis clinic with an inflammatory dermatosis localized predominantly to the external auditory canal. Of these patients, four were found to have an allergic contact dermatitis which was exacerbating their dermatitis. All were allergic to one or more corticosteroids and topical antibiotics used in the treatment of their dermatitis. We would suggest that hypersensitivity to topical corticosteroids and other medicaments be considered in patients with otitis externa which fails to respond to treatment.

Keywords

Otitis externaDermatitis, contactOintmentsHydrocortisone, topical
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 107 , Issue 7 , July 1993 , pp. 597 - 599
Copyright
Copyright © JLO (1984) Limited 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Alani, M. D., Alani, S. D. (1972) Allergic contact dermatitis to corticosteroids. Annals of Allergy 30: 181–185Google ScholarPubMed
Burden, A. D., Beck, M. H. (1992) Contact hypersensitivity to topical corticosteroids. British Journal of Dermatology 127: 497–500CrossRefGoogle ScholarPubMed
Dooms-Goossens, A., Morren, M. (1992) Results of routine patch testing with corticosteroid series in 2073 patients. Contact Dermatitis 26: 182–191CrossRefGoogle ScholarPubMed
Fisher, A. A. (1986) Contact Dermatitis, 3rd edn., Lea and Febiger, Philadelphia pp. 85–87.Google Scholar
Guin, J. D. (1984) Contact sensitivity to topical corticosteroids. Journal of the American Academy of Dermatology 10: 773–782CrossRefGoogle ScholarPubMed
Jensen, C. O., Allen, H. J., Mordecai, L. R. (1966) Neomycin contact dermatitis superimposed on otitis externa. Journal of the American Medical Association 195: 175.Google ScholarPubMed
Kirton, V, Munro-Ashman, D. (1965) Contact dermatitis from neomycin and framycetin. Lancet i: 138–139CrossRefGoogle Scholar
Lauerma, A. I., Rasanen, L., Reunala, T, Reitamo, S. (1990) Langerhans cells but not monocytes are capable of antigen presentation in vitro in corticosteroid contact hypersensitivity. British Journal of Dermatology 123: 699–705CrossRefGoogle Scholar
Lauerma, A. I. (1991) Screening of corticosteroid contact hypersensitivity: comparison of tixocortol pivalate, hydrocortisone-17- butyrate and hydrocortisone. Contact Dermatitis 24: 123–130CrossRefGoogle ScholarPubMed
Lauerma, A. I., Reitamo, S., Maibach, H. I. (1991) Systemic hydrocortisone/cortisol induces allergic skin reactions in presensitized subjects. Journal of the American Academy of Dermatology 24: 182–185CrossRefGoogle ScholarPubMed
Lembo, G., Nappa, P., Bajato, N., Pucci, V., Ayala, F. (1988) Contact sensitivity in otitis extema. Contact Dermatitis 19: 64–65CrossRefGoogle Scholar
Pirila, V. (1975) Chamber test versus patch test for epicutaneous testing. Contact Dermatitis 1: 48–52CrossRefGoogle ScholarPubMed
Reitamo, S., Lauerma, A. I., Stubb, S., Kayhko, K., Visa, K., For strom, L. (1986) Delayed hypersensitivity to topical corticosteroids. Journal of the American Academy of Dermatology 14: 582–589CrossRefGoogle ScholarPubMed
Sasaki, E. (1990) Corticosteroid sensitivity and cross-sensitivity. Contact Dermatitis 23: 306–315CrossRefGoogle ScholarPubMed
Wilkinson, D. S., Fregert, S., Magnusson, B., Bandmann, H. J., Calnan, C. D., Cronin, E., Hjorth, N., Maibach, H. I., Malten, K. E., Meneghini, C. L., Pirila, V. (1970) Terminology of contact dermatitis. Ada Dermato-Venereol (Stockholm) 50: 287–292Google ScholarPubMed
Wilkinson, S. M., Cartwright, P. H., English, J. S. C. (1990) The significance of tixocortol-pivalate positive patch tests in leg ulcer patients. Contact Dermatitis 23: 120–121CrossRefGoogle ScholarPubMed
Wilkinson, S. M., English, J. S. C. (1991) Hydrocortisone sensitivity: a prospective study into the value of tixocortol-pivalate and hydrocortisone acetate as patch test markers. Contact Dermatitis 25: 132–133CrossRefGoogle ScholarPubMed
Wilkinson, S. M, Cartwright, P. H., English, J. S. C. (1991) Hydrocortisone: an important cutaneous allergen. Lancet 337: 761–762CrossRefGoogle ScholarPubMed
Wilkinson, S. M., English, J. S. C. (1992) Hydrocortisone sensitivity: clinical features of 59 cases. Journal of the American Academy of Dermatology 27: 683–687CrossRefGoogle ScholarPubMed