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Histological findings following oestrogen treatment of hereditary haemorrhagic telangiectasia

A controlled double-blind investigation

Published online by Cambridge University Press:  29 June 2007

P. Vase  and
M. Lorentzen
P. Vase*
Affiliation:
Odense, Denmark
M. Lorentzen
Affiliation:
Institute of Pathology, Odense University Hospital, 5000 Odense C, Denmark
*
ENT Department, Odense University Hospital, DK-5000 Odense C, Denmark.
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Abstract

In a controlled investigation of 22 patients with hereditary haemorrhagic telangiectasia, an evaluation has been carried out of the connective tissue content of muco-substances prior to and after treatment with oral oestrogen (oestradiol valerate 4 mg. daily). The clinical condition of the patients, all of whom had haemorrhagic anaemia, was evaluated by the frequency of epistaxis and by blood analyses. No effect of treatment could be demonstrated by means of histochemical, clinical or laboratory methods.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 97 , Issue 5 , May 1983 , pp. 427 - 429
Copyright
Copyright © JLO (1984) Limited 1983

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