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Haemostasis and analgesia with autologous platelet-rich plasma in tonsillectomy

Published online by Cambridge University Press:  12 July 2019

M N Chettri ,
S K Jayagandhi ,
Y Konyak ,
P Sobita ,
M M Singh  and
A M Singh
M N Chettri*
Affiliation:
Department of ENT, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok, India
S K Jayagandhi
Affiliation:
Department of ENT, Sri Rama Chandra Medical College, Chennai, India
Y Konyak
Affiliation:
Department of ENT, Mon District Hospital, Nagaland, India
P Sobita
Affiliation:
Department of ENT, Regional Institute of Medical Sciences, Imphal, India
M M Singh
Affiliation:
Department of ENT, Jawaharlal Nehru Institute of Medical Sciences, Imphal, India
A M Singh
Affiliation:
Department of Immunohaematology and Blood Transfusion, Regional Institute of Medical Sciences, Imphal, India
*
Author for correspondence: Dr Mohonish N Chettri, Department of ENT, Sikkim Manipal Institute of Medical Sciences, Level 4 of Central Referral Hospital, Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok 737102, Sikkim, India E-mail: [email protected]
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Abstract

Objective

A single-centre, single-blinded prospective experimental study was conducted to determine the effectiveness of autologous platelet-rich plasma applied to the tonsillar bed post-operatively in reducing post-operative pain and haemorrhage.

Methods

Platelet-rich plasma, prepared prior to surgery, was applied with calcium gluconate to one randomly chosen tonsillar fossa. Pain and haemorrhage were analysed, using a visual analogue scale and a pre-defined grading scale respectively, four times on the day of surgery at 2-hourly intervals, and thrice on the following day.

Results

The pain score and haemorrhage grade on the test side were lower than on the control side. These findings were statistically significant.

Conclusion

This pilot study, conducted in India, revealed valid positive results for a promising new technology. The manual preparation of platelet-rich plasma could be automated in the future to allow a larger sample size.

Keywords

TonsillectomyPlatelet-Rich PlasmaHemorrhageVisual Analog Scale
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 133 , Issue 7 , July 2019 , pp. 615 - 621
Copyright
Copyright © JLO (1984) Limited, 2019 

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Footnotes

Dr M N Chettri takes responsibility for the integrity of the content of the paper

Presented at the 66th National Conference of the Association of Otorhinolaryngologists of India, 11 January 2014, Mysore, India.

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