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Granulomatous cutaneous T-cell lymphoma of the neck

Published online by Cambridge University Press:  29 June 2007

J. D. Blanshard*
Affiliation:
Departments of Otolaryngology, Royal United Hospital, Bath.
T. I. Macleod
Affiliation:
Departments of Histopathology, Royal United Hospital, Bath.
S. T. Baer
Affiliation:
Departments of Otolaryngology, Royal United Hospital, Bath.
R. J. Canter
Affiliation:
Departments of Otolaryngology, Royal United Hospital, Bath.
*
J. D. Blanshard, F. R.C.S., Department of Otolaryngology, Bristol Royal Infirmary, Bristol, BS2 8HW.

Abstract

A case of cutaneous T-cell lymphoma is presented in which the diagnosis was obscured by a concomitant granulomatous infiltrate. A working diagnosis of tuberculosis delayed appropriate treatment for several months over which time rapid progression of the disease was seen. Inclusion of overlying skin in the repeat biopsies yielded the histological information to establish the correct diagnosis and there was rapid regression on completion of a course of radiotherapy.

Type
View from Beneath: Pathology in Focus
Copyright
Copyright © JLO (1984) Limited 1992

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References

Berger, C. L., Warburton, D., Raafat, J., LoGerfo, P., Edelson, R. L. (1979) Cutaneous T-cell lymphoma: Neoplasm of T-cells with helper activity. Blood, 53: 642651.CrossRefGoogle ScholarPubMed
Braylan, R. C. Long, J. C. Jaffe, E. S., Greco, F. A., Orr, S. L., Berard, C. W. (1977) Malignant lymphoma obscured by concomitant extensive epithelioid granulomas. Cancer, 39: 11461155.3.0.CO;2-X>CrossRefGoogle ScholarPubMed
Dabski, K., Stoll, H. L. (1987) Granulomatous reactions in Mycosis fungoides. Journal of Surgical Oncology, 34: 217229.CrossRefGoogle ScholarPubMed
Edelson, R. L. (1979) Cutaneous T cell lymphoma. In Dermatology update (Moschella, S., ed.) Elsevier Press: New York, pp. 195207.Google Scholar
Edelson, R. L. (1980 a) Cutaneous T cell lymphoma: Mycosis fungoides, Sezary syndrome and other variants. Journal of the American Academy of Dermatology, 2: 89106.CrossRefGoogle ScholarPubMed
Edelson, R. L. (1980 b) Cutaneous T-cell lymphoma. Journal ofDermatologic Surgery and Oncology, 6: 358368.CrossRefGoogle ScholarPubMed
Edelson, R. L., Raafat, J., Berger, C. L., Grossman, M., Troyer, C. (1979 a) Antithymocyte globulin in the management of cutaneous T cell lymphoma. Cancer Treatment Reports, 63: 675680.Google ScholarPubMed
Epstein, E. H. Jr, Levin, D. L., Croft, J. D. Jr, Lutzner, M. A. (1972) Mycosis fungoides. Survival, prognostic features, response to therapy and autopsy findings. Medicine (Baltimore), 51: 6172.CrossRefGoogle ScholarPubMed
Flaxman, B. A., Koumans, J. A. D., Ackerman, A. B. (1983) Granulomatous mycosis fungoides: a 14-year follow up of a case. American Journal of Dermatopathology, 5: 145151.CrossRefGoogle ScholarPubMed
Fuks, Z. K., Bagshaw, M. A., Farber, E. M. (1973) Prognostic signs and the management of Mycosis fungoides. Cancer, 32: 13851395.3.0.CO;2-#>CrossRefGoogle ScholarPubMed
Hoppe, R. T., Fuks, Z. K., Bagshaw, M. A. (1979) Radiation therapy in the management of cutaneous T-cell lymphomas. Cancer Treatment Reports, 63: 625632.Google ScholarPubMed
LeBoit, P. E., Zackheim, H. S., White, C. R. (1988) Granulomatous variants of cutaneous T-cell lymphoma. American Journal of Surgical Pathology, 12: 8395.CrossRefGoogle ScholarPubMed
O'Connell, M. J., Schimpff, S. C. Kirschner, R. H., Abt, A. B., Wiernik, P. H. (1975) Epithelioid granulomas in Hodgkin disease: a favourable prognostic sign? Journal of the American Medical Association, 233: 886889.CrossRefGoogle Scholar
Randle, H. W., Banks, P. M., Winkelmann, R. K. (1980) Cutaneous granulomas in malignant lymphoma. Archives of Dermatology, 116: 441443.CrossRefGoogle ScholarPubMed
Sandbank, M., Katzenellenbogen, I. (1968) Mycosis fungoides of prolonged duration in siblings. Archives of Dermatology, 98: 620627.CrossRefGoogle ScholarPubMed
Vonderheid, E. C. Van Scott, E. J., Wallner, P. E., Johnson, W. C. (1979) A 10-year experience with topical mechlorethamine for Mycosis fungoides: comparison with patients treated by total skin electron-beam radiation therapy. Cancer Treatment Reports, 63: 681689.Google ScholarPubMed