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Framingham risk score is associated with hearing outcomes in patients with idiopathic sudden sensorineural hearing loss

Published online by Cambridge University Press:  19 May 2020

Y-S Chang
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
S Park
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
M K Lee
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
Y C Rah
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
J Choi*
Affiliation:
Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Republic of Korea
*
Author for correspondence: Dr June Choi, Department of Otorhinolaryngology – Head and Neck Surgery, Korea University College of Medicine, 123, Jeokgeum-ro (Gojan-dong), Danwon-gu, Ansan-si, Gyeonggi-do15355, Republic of Korea E-mail: [email protected] Fax: +81 31 412 5174

Abstract

Objective

To assess the Framingham risk score as a prognostic tool for idiopathic sudden sensorineural hearing loss patients.

Methods

Medical records were reviewed for unilateral idiopathic sudden sensorineural hearing loss patients between January 2010 and October 2017. The 10-year risk of developing cardiovascular disease was calculated. Patients were subdivided into groups: group 1 – Framingham risk score of less than 10 per cent (n = 28); group 2 – score of 10 to less than 20 per cent (n = 6); and group 3 – score of 20 per cent or higher (n = 5).

Results

Initial pure tone average and Framingham risk score were not significantly associated (p = 0.32). Thirteen patients in group 1 recovered completely (46.4 per cent), but none in groups 2 and 3 showed complete recovery. Initial pure tone average and Framingham risk score were significantly associated in multivariable linear regression analysis (R2 = 0.36). The regression coefficient was 0.33 (p = 0.003) for initial pure tone average and −0.67 (p = 0.005) for Framingham risk score.

Conclusion

Framingham risk score may be useful in predicting outcomes for idiopathic sudden sensorineural hearing loss patients, as those with a higher score showed poorer hearing recovery.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited, 2020

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Footnotes

Dr J Choi takes responsibility for the integrity of the content of the paper

Presented at the International Congress of Otorhinolaryngology – Head and Neck Surgery (‘ICORL-HNS’) in conjunction with 93rd Annual Congress of Korean Society of Otorhinolaryngology – Head and Neck Surgery, 25–28 April 2019, Seoul, Korea.

References

Wilson, WR, Byl, FM, Laird, N. The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A double-blind clinical study. Arch Otolaryngol 1980;106:772–610.1001/archotol.1980.00790360050013CrossRefGoogle ScholarPubMed
Wu, CS, Lin, HC, Chao, PZ. Sudden sensorineural hearing loss: evidence from Taiwan. Audiol Neurootol 2006;11:151–610.1159/000091198CrossRefGoogle ScholarPubMed
Nosrati-Zarenoe, R, Arlinger, S, Hultcrantz, E. Idiopathic sudden sensorineural hearing loss: results drawn from the Swedish national database. Acta Otolaryngol 2007;127:1168–7510.1080/00016480701242477CrossRefGoogle ScholarPubMed
Byl, FM Jr. Sudden hearing loss: eight years' experience and suggested prognostic table. Laryngoscope 1984;94:647–6110.1288/00005537-198405000-00014CrossRefGoogle ScholarPubMed
Chau, JK, Lin, JR, Atashband, S, Irvine, RA, Westerberg, BD. Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss. Laryngoscope 2010;120:1011–21Google ScholarPubMed
Huy, PT, Sauvaget, E. Idiopathic sudden sensorineural hearing loss is not an otologic emergency. Otol Neurotol 2005;26:89690210.1097/01.mao.0000185071.35328.6dCrossRefGoogle Scholar
Narozny, W, Kuczkowski, J, Kot, J, Stankiewicz, C, Sicko, Z, Mikaszewski, B. Prognostic factors in sudden sensorineural hearing loss: our experience and a review of the literature. Ann Otol Rhinol Laryngol 2006;115:553–810.1177/000348940611500710CrossRefGoogle Scholar
Suzuki, H, Mori, T, Hashida, K, Shibata, M, Nguyen, KH, Wakasugi, T et al. Prediction model for hearing outcome in patients with idiopathic sudden sensorineural hearing loss. Eur Arch Otorhinolaryngol 2011;268:49750010.1007/s00405-010-1400-2CrossRefGoogle ScholarPubMed
Cvorovic, L, Deric, D, Probst, R, Hegemann, S. Prognostic model for predicting hearing recovery in idiopathic sudden sensorineural hearing loss. Otol Neurotol 2008;29:464–910.1097/MAO.0b013e31816fdcb4CrossRefGoogle ScholarPubMed
Kuhn, M, Heman-Ackah, SE, Shaikh, JA, Roehm, PC. Sudden sensorineural hearing loss: a review of diagnosis, treatment, and prognosis. Trends Amplif 2011;15:9110510.1177/1084713811408349CrossRefGoogle Scholar
Aimoni, C, Bianchini, C, Borin, M, Ciorba, A, Fellin, R, Martini, A et al. Diabetes, cardiovascular risk factors and idiopathic sudden sensorineural hearing loss: a case-control study. Audiol Neurootol 2010;15:111–1510.1159/000231636CrossRefGoogle ScholarPubMed
Marcucci, R, Alessandrello Liotta, A, Cellai, AP, Rogolino, A, Berloco, P, Leprini, E et al. Cardiovascular and thrombophilic risk factors for idiopathic sudden sensorineural hearing loss. J Thromb Haemost 2005;3:929–3410.1111/j.1538-7836.2005.01310.xCrossRefGoogle ScholarPubMed
Fukui, M, Kitagawa, Y, Nakamura, N, Kadono, M, Mogami, S, Ohnishi, M et al. Idiopathic sudden hearing loss in patients with type 2 diabetes. Diabetes Res Clin Pract 2004;63:205–1110.1016/j.diabres.2003.09.013CrossRefGoogle ScholarPubMed
Chang, Y-S, Choi, JE, Ahn, J, Ryu, N-G, Moon, IJ, Hong, SH et al. Framingham risk score as a prognostic predictor of sudden sensorineural hearing loss: a preliminary study. Ann Otol Rhinol Laryngol 2017;126:382–710.1177/0003489417694910CrossRefGoogle ScholarPubMed
Bulğurcu, S, Şahin, B, Akgül, G, Arslan, İB, Çukurova, İ. The effects of prognostic factors in idiopathic sudden hearing loss. Int Arch Otorhinolaryngol 2018;22:33–7Google ScholarPubMed
Lee, HS, Lee, YJ, Kang, BS, Lee, BD, Lee, JS. A clinical analysis of sudden sensorineural hearing loss cases. Korean J Audiol 2014;18:697510.7874/kja.2014.18.2.69CrossRefGoogle ScholarPubMed
D'Agostino, RB Sr, Vasan, RS, Pencina, MJ, Wolf, PA, Cobain, M, Massaro, JM et al. General cardiovascular risk profile for use in primary care: the Framingham Heart Study. Circulation 2008;117:743–5310.1161/CIRCULATIONAHA.107.699579CrossRefGoogle ScholarPubMed
Ho, KK, Pinsky, JL, Kannel, WB, Levy, D. The epidemiology of heart failure: the Framingham Study. J Am Coll Cardiol 1993;22(4 suppl A):613A10.1016/0735-1097(93)90455-ACrossRefGoogle ScholarPubMed
Wilson, PW, D'Agostino, RB, Levy, D, Belanger, AM, Silbershatz, H, Kannel, WB. Prediction of coronary heart disease using risk factor categories. Circulation 1998;97:1837–4710.1161/01.CIR.97.18.1837CrossRefGoogle ScholarPubMed
Siegel, LG. The treatment of idiopathic sudden sensorineural hearing loss. Otolaryngol Clin North Am 1975;8:467–7310.1016/S0030-6665(20)32783-3CrossRefGoogle ScholarPubMed
Toth, PP. Subclinical atherosclerosis: what it is, what it means and what we can do about it. Int J Clin Pract 2008;62:1246–5410.1111/j.1742-1241.2008.01804.xCrossRefGoogle Scholar
Li, F, Wang, X. Relationship between Framingham risk score and subclinical atherosclerosis in carotid plaques: an in vivo study using multi-contrast MRI. Sci China Life Sci 2017;60:23–710.1007/s11427-016-0385-5CrossRefGoogle Scholar
Jung, SY, Shim, HS, Hah, YM, Kim, SH, Yeo, SG. Association of metabolic syndrome with sudden sensorineural hearing loss. JAMA Otolaryngol Head Neck Surg 2018;144:308–1410.1001/jamaoto.2017.3144CrossRefGoogle ScholarPubMed
Nagaoka, J, Anjos, MF, Takata, TT, Chaim, RM, Barros, F, Penido Nde, O. Idiopathic sudden sensorineural hearing loss: evolution in the presence of hypertension, diabetes mellitus and dyslipidemias. Braz J Otorhinolaryngol 2010;76:363–910.1590/S1808-86942010000300015CrossRefGoogle ScholarPubMed
Rudack, C, Langer, C, Stoll, W, Rust, S, Walter, M. Vascular risk factors in sudden hearing loss. Thromb Haemost 2006;95:454–61CrossRefGoogle ScholarPubMed
Mosnier, I, Stepanian, A, Baron, G, Bodenez, C, Robier, A, Meyer, B et al. Cardiovascular and thromboembolic risk factors in idiopathic sudden sensorineural hearing loss: a case-control study. Audiol Neurootol 2011;16:556610.1159/000312640CrossRefGoogle ScholarPubMed
Seo, YJ, Choi, JY, Moon, IS. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio: novel markers for diagnosis and prognosis in patients with idiopathic sudden sensorineural hearing loss. Dis Markers 2014;2014:70280710.1155/2014/702807CrossRefGoogle ScholarPubMed
Balta, S, Demırkol, S, Kucuk, U. The platelet lymphocyte ratio may be useful inflammatory indicator in clinical practice. Hemodial Int 2013;17:668–9Google ScholarPubMed
Chen, L, Zhang, G, Zhang, Z, Wang, Y, Hu, L, Wu, J. Neutrophil-to-lymphocyte ratio predicts diagnosis and prognosis of idiopathic sudden sensorineural hearing loss: a systematic review and meta-analysis. Medicine (Baltimore) 2018;97:e12492CrossRefGoogle ScholarPubMed
Kum, RO, Ozcan, M, Baklaci, D, Kum, NY, Yilmaz, YF, Unal, A et al. Investigation of neutrophil-to-lymphocyte ratio and mean platelet volume in sudden hearing loss. Braz J Otorhinolaryngol 2015;81:636–4110.1016/j.bjorl.2015.08.009CrossRefGoogle ScholarPubMed
Seaoud, E, Shawky, A. Framingham risk score and extent of atherosclerosis in non-diabetic patients with suspected coronary artery disease. J Ind Coll Cardiol 2018;8:182010.1016/j.jicc.2017.12.001CrossRefGoogle Scholar
Berrettini, S, Seccia, V, Fortunato, S, Forli, F, Bruschini, L, Piaggi, P et al. Analysis of the 3-dimensional fluid-attenuated inversion-recovery (3D-FLAIR) sequence in idiopathic sudden sensorineural hearing loss. JAMA Otolaryngol Head Neck Surg 2013;139:456–6410.1001/jamaoto.2013.2659CrossRefGoogle ScholarPubMed
Weisel, JW. Fibrinogen and fibrin. Adv Protein Chem 2005;70:247–9910.1016/S0065-3233(05)70008-5CrossRefGoogle ScholarPubMed