Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-26T18:57:29.716Z Has data issue: false hasContentIssue false
  • English
  • Français

Familial paraganglioma

Published online by Cambridge University Press:  29 June 2007

S. M. Wharton  and
A. Davis
S. M. Wharton*
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Queen Alexandra Hospital, Cosham, Portsmouth, UK
A. Davis
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Queen Alexandra Hospital, Cosham, Portsmouth, UK
*
Address for correspondence: Dr S. M. Wharton, Department of Otorhinolaryngology, Head and Neck Surgery, Queen Alexandra Hospital, Cosham, Portsmouth, Hants.
Get access Rights & Permissions [Opens in a new window]

Abstract

Non-secreting paragangliomas are rare tumours usually present in the head and neck. We describe an unusual case of familial paraganglioma with cranial nerve palsies. After exhaustive investigation, a vagal paraganglioma was found and excised. The positive family history of paraganglioma was of significance, although this was only present in one of five generations. The diagnosis and management of non-secreting paragangliomas is discussed.

Keywords

ParagangliomaVagus nerveFamily
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 7 , July 1996 , pp. 688 - 690
Copyright
Copyright © JLO (1984) Limited 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Anderson, R. J., Lynch, H. T. (1993) Familial risk for neuroendocrine tumours. Current Opinion in Oncology 5: 75–84.Google Scholar
Coia, L. R., Fazekas, J. T., Farb, S. N. (1981) Familial chemodectoma. International Journal of Radiation and Biological Physics 7: 949–952.CrossRefGoogle ScholarPubMed
Deshmukh, N., Horbowyj, R. (1994) Paraganglioma of the vagus nerve masquerading as a carotid'body tumour. Military Medicine 159: 166–168.CrossRefGoogle Scholar
Geysens, P., D'Haenens, P., van Steenberge, R., Wilms, G., Baert, A. L. (1989) Familial occurrence of paragangliomas. Journal Beige De Radiologie 72: 95–99.Google ScholarPubMed
Granger, J. K., Houn, H.-Y. (1990) Bilateral familial carotid body paragangliomas. Report of a case with DNA flow cytometric and cytogenetic analyses. Archives of Pathology and Laboratory Medicine 114: 1272–1275.Google ScholarPubMed
Irving, R. M., Moffat, D. A., Maher, E. R. (1995) Genetics of familial and non-familial skull base tumours. Clinical Otolaryngology 20: 5–11.CrossRefGoogle ScholarPubMed
Powell, S., Peters, N., Harmer, C. (1992) Chemodectoma of the head and neck: Results of treatment in 84 patients. International Journal of Radiation and Biological Physics 22: 919–924.CrossRefGoogle ScholarPubMed
Ruijs, J. H., van Waes, G., Deltaas, G., Hoekstra, H., Nulder, P. H., Veldman, R. E. (1978) Screening of a family for chemodectoma. Radiologica Clinica 42: 114–123.Google Scholar
van der Mey, A. G. L., Maaswinkel-Mooy, P. D., Cornelisse, C. J., Schmidt, P. H., van der Kamp, J. J. P. (1989) Genomic imprinting in hereditary glomus tumours: Evidence for new genetic theory. Lancet ii: 1291–1294.CrossRefGoogle Scholar
Westbury, G. (1960) The management of carotid body tumours with a report of seven cases. British Journal of Surgery 47: 605–611.CrossRefGoogle ScholarPubMed