Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-29T04:44:02.746Z Has data issue: false hasContentIssue false
  • English
  • Français

Facial nerve schwannoma: nerve fibre dissemination

Published online by Cambridge University Press:  29 June 2007

Mutawakel Hajjaj  and
Fred H. Linthicum Jr
Mutawakel Hajjaj
Affiliation:
Senior Registrar, Choud Hospital, Medina, Saudi Arabia
Fred H. Linthicum Jr*
Affiliation:
Head, Department of Histopathology, House Ear Institute, Los Angeles, USA
*
Address for correspondence: Fred H. Linthicum Jr., M.D., House Ear Institute, 2100 West Third Street, Los Angeles, California 90057, USA. Fax: (213) 413-6739.
Get access Rights & Permissions [Opens in a new window]

Abstract

Biopsy of a middle ear mass can lead to facial paralysis when the mass is a facial nerve schwannoma. Immunostaining techniques were used to determine if nerve fibres might be present within the tumour mass. Nerve fibres were found to be widely disseminated throughout the tumour in eight of 23 facial nerve schwannomas. Antibodies to neurofilaments demonstrated single fibres, or small groups of fibres, that are very difficult to see with routine haematoxylin and eosin stains. The presence of fibres throughout some tumours makes biopsy of them likely to result in facial dysfunction.

Keywords

Facial nerve schwannomaFacial paralysisImmunohistochemistry
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 110 , Issue 7 , July 1996 , pp. 632 - 633
Copyright
Copyright © JLO (1984) Limited 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Jung, T. K., Jun, B.-H., Shea, D., Paparella, M., (1986) Primary and secondary tumors of the facial nerve. A temporal bone study, Otolaryngology– Head and Neck Surgery 121: 1269–1273.CrossRefGoogle Scholar
O'Donoghue, G. M., Braekmann, D. E., House, J. W., Jackler, R. J. (1989) Neuromas of the facial nerve. American Journal of Otolaryngology 10:49–54.Google ScholarPubMed
Pulec, J. L., (1972) sFacial nerve neuroma. Laryngoscope 82:1160–1176.Google Scholar
Satio, H., Baxter, A. (1972) Undiagnosed intratemporal facial nerve neurolemommas:Archives of Otolaryngology, Head and Neck Surgery 95: 415–419.Google Scholar
Schmidt, C., (1930) Neurinom des nervus faeialis. Zentralblatte fur Hals-Nasan-und Ohrenheilkunde 116:329.Google Scholar
Shelton, A. (1994) Facial nerve tumors. In Otologic Surgery (Braekmann, D. B., Shelton, C. S., Arriaga, M. A., eds.), W. B. Saunders Co, Philadelphia, p 415.Google Scholar
Shi, S. R., Key, M., Karla, K. (1991) Antigen retrieval in formalin-fixed, paraffin-embedded tissues; an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. Journal of Histochemistry and Cytochemistry 39:741–748.CrossRefGoogle ScholarPubMed