Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-26T17:58:06.553Z Has data issue: false hasContentIssue false

Extranodal Rosai-Dorfman disease: an uncommon cause of persistent nodule in the ear

Published online by Cambridge University Press:  29 June 2007

W. Y. W. Tsang*
Affiliation:
Institutes of Pathology and Otolarygnology, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong.
J. K. C. Chan
Affiliation:
Institutes of Pathology and Otolarygnology, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong.
W. K. Ho
Affiliation:
Institutes of Pathology and Otolarygnology, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong.
H. C. Yu
Affiliation:
Institutes of Pathology and Otolarygnology, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong.
L. T. C. Chow
Affiliation:
Institutes of Pathology and Otolarygnology, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong.
*
Dr W. Y. W. Tsang, Institute of Pathology, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong.

Abstract

A 40-year-old woman presented with a nodule over the tragus of the right ear. A biopsy was initially reported as showing non-specific inflammation. In view of the persistence of the lesion, the histological material was reviewed, leading to revision of the diagnosis to Rosai-Dorfman disease, a diagnosis further confirmed by immunoreactivity of the histiocytes for s-100 protein. This case represented the extranodal form of Rosai-Dorfman disease in the absence of lymph node involvement.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Chan, J., Mak, K. L., Saw, D. (1985) Sinus histiocytosis with massive lymphadenopathy, a report of two cases in Chinese. Pathology, 417: 609612.CrossRefGoogle Scholar
Eisen, R. N., Buckley, P. J., Rosai, J. (1990) Immunophenotypic characterization of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). Seminars in Diagnostic Pathology, 7: 7482.Google ScholarPubMed
Foucar, E., Rosai, J., Dorfman, R. (1990) Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). Review of the entity. Seminars in Diagnostic Pathology, 7: 1973.Google ScholarPubMed
Rosai, J., Dorfman, R. F (1969) Sinus histiocytosis with massive lymphadenopathy, a newly recognized benign clinicopathological entity. Archives of Pathology, 87: 6370.Google ScholarPubMed