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Ewing's sarcoma of the masseter muscle

Published online by Cambridge University Press:  31 May 2011

H A Osborn ,
B Wehrli ,
J H Franklin  and
K Fung
H A Osborn
Affiliation:
Schulich School of Medicine, University of Western Ontario, London, Canada
B Wehrli
Affiliation:
Department of Pathology, London Health Sciences Centre, Ontario, Canada
J H Franklin
Affiliation:
Department of Otolaryngology, London Health Sciences Centre, Ontario, Canada
K Fung*
Affiliation:
Department of Otolaryngology, London Health Sciences Centre, Ontario, Canada
*
Address for correspondence: Dr. Kevin Fung, Department of Otolaryngology – Head and Neck Surgery, London Health Sciences Centre – Victoria Hospital, 800 Commissioners Road East London, Ontario, CanadaN6A 5W9 E-mail: [email protected]
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Abstract

Objective:

To present a case of extraskeletal Ewing's sarcoma originating in the masseter muscle, and to review the diagnosis and management of these rare tumours.

Methods:

Case report and literature review.

Results:

We report a patient with Ewing's sarcoma of the masseter muscle with mandibular invasion. She was treated with induction chemotherapy, salvage surgery and free flap reconstruction.

Conclusion:

This case highlights the management of these rare tumours. Aggressive multi-modal treatment, including multi-agent chemotherapy, surgical resection and irradiation, appears to offer the best prognosis. Contemporary reconstructive techniques can restore function and form in cases with challenging defects.

Keywords

Sarcoma, Ewing'sPathologyHead And Neck Neoplasms, SurgeryMasseter MuscleCombined Modality Treatment
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 9 , September 2011 , pp. 978 - 981
Copyright
Copyright © JLO (1984) Limited 2011

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References

1Cotterill, SJ, Ahrens, S, Paulussen, M, Jurgens, HF, Voute, PA, Gadner, H et al. Prognostic factors in Ewing's tumor of bone: analysis of 975 patients from the European Intergroup Cooperative Ewing's Sarcoma Study Group. J Clin Oncol 2000;18:3108–14Google Scholar
2Allam, A, El-Husseiny, G, Khafaqa, Y, Kandil, A, Gray, A, Ezzat, A et al. Ewing's sarcoma of the head and neck: a retrospective analysis of 24 cases. Sarcoma 1999;3:11–15CrossRefGoogle ScholarPubMed
3Siegal, GP, Oliver, WR, Reinus, WR, Gilula, LA, Foulkes, MA, Kissane, JM et al. Primary Ewing's sarcoma involving the bones of the head and neck. Cancer 1987;60:2829–403.0.CO;2-S>CrossRefGoogle ScholarPubMed
4Ali, S, MacKenzie, K, Reid, R, O'Neill, G, Ganly, I. Cervical extraskeletal Ewing's sarcoma: case report demonstrating radiological features and management. J Laryngol Otol 2008;122:998–1001Google Scholar
5Kinsella, TJ, Triche, TJ, Dickman, PS, Costa, J, Tepper, JE, Glaubiger, D. Extraskeletal Ewing' s sarcoma: results of combined modality treatment. J Clin Oncol 1983;1:489–95CrossRefGoogle ScholarPubMed
6Cho, SI, Park, YH, Cho, JH, Ryoo, BY, Yang, SH, Youn, SM et al. Extraskeletal Ewing's sarcoma of the head and neck presenting as blindness. Korean J Intern Med 2007;22:133–7Google Scholar
7Chao, TK, Chang, YL, Sheen, TS. Extraskeletal Ewing's sarcoma of the scalp. J Laryngol Otol 2000;114:73–5Google Scholar
8Yang, YS, Hong, KH. Extraskeletal Ewing's sarcoma of the larynx. J Laryngol Otol 2004;118:62–4CrossRefGoogle ScholarPubMed
9Weinreb, I, Goldstein, D, Perez-Ordonez, B. Primary extraskeletal Ewing family tumor with complex epithelial differentiation: a unique case arising in the lateral neck presenting with Horner syndrome. Am J Surg Pathol 2008;32:1742–8Google Scholar
10Mills, SE. Neuroectodermal neoplasms of the head and neck with emphasis on neuroectodermal carcinomas. Mod Pathol 2002;15:264–78CrossRefGoogle ScholarPubMed
11Ewing, J. Diffuse endothelioma of bone. Proc N Y Pathol Soc 1921;21:17–24Google Scholar
12Tefft, M, Vawter, GF, Mitus, A. Paravertebral “round cell” tumors in children. Radiology 1969;92:1501–9CrossRefGoogle ScholarPubMed
13O'Keefe, F, Lorigan, JG, Wallace, S. Radiological features of extraskeletal Ewing sarcoma. Br J Radiol 1990;63:456–60CrossRefGoogle Scholar
14Heare, T, Hensley, M, Dell'Orfano, S. Bone tumors: osteosarcoma and Ewing's sarcoma. Curr Opin Pediatr 2009;21:365–72CrossRefGoogle ScholarPubMed
15Zagar, TM, Triche, TJ, Kinsella, T. Extraosseous Ewing's sarcoma: 25 years later. J Clin Oncol 2008;26:4230–2CrossRefGoogle ScholarPubMed
16Venkitaraman, R, George, M, Ramanan, SG, Sagar, TG. A single institution experience of combined modality management of extra skeletal Ewings sarcoma. World J Surg Onc 2007;5:3CrossRefGoogle ScholarPubMed
17Bacci, G, Longhi, A, Ferrari, S, Mercuri, M, Barbieri, E, Bertoni, F et al. Pattern of relapse in 290 patients with non-metastatic Ewing's sarcoma family tumors treated at a single institution with adjuvant and neoadjuvant chemotherapy between 1972 and 1999. Eur J Surg Onc 2006;32:974–9Google Scholar
18Verrill, MW, Judson, IR, Harmer, CL, Fisher, C, Thomas, JM, Wiltshaw, E. Ewing's sarcoma and primitive neuroectodermal tumor in adults: are they different from Ewing's sarcoma and primitive neuroectodermal tumor in children? J Clin Oncol 1997;15:2611–21Google Scholar
19Paulino, AC, Nguyen, TX, Mai, WY. An analysis of primary site control and late effects according to local control modality in non-metastatic Ewing sarcoma. Pediatr Blood Cancer 2007;48:423–9CrossRefGoogle ScholarPubMed