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The effects of fibrin tissue adhesive on the middle ear

Published online by Cambridge University Press:  29 June 2007

D. Katzke*
Affiliation:
Department of Otorhinolaryngology, University of Tübingen, West Germany.
A. Pusalkar*
Affiliation:
Department of Otorhinolaryngology, University of Tübingen, West Germany.
E. Steinbach*
Affiliation:
Department of Otorhinolaryngology, University of Tübingen, West Germany.
*
Department of Otorhinolarygology, University of Tabingen, Silcherstr. 5, D-7400 Tübingen, W. Germany.
Department of Otorhinolarygology, University of Tabingen, Silcherstr. 5, D-7400 Tübingen, W. Germany.
Department of Otorhinolarygology, University of Tabingen, Silcherstr. 5, D-7400 Tübingen, W. Germany.

Abstract

This study investigated the effects of fibrin glue (‘Tissucol’, Immuno Pty. Ltd.) in the middle and inner ear. Small amounts of the adhesive were used in 36 operations performed on 18 rabbits. The light microscopic examination of these ears four, eight and 12 weeks after surgery showed that the adhesive was well tolerated and that it did not have any toxic effecton on the middle ear or membranous labyrinth. The fibrin tissue adhesive can therefore safely be used to facilitate reconstructive middle-ear surgery and, with the aid of fasic, also for the closure of labyrinthine fistulae; or to achieve a definite seal of the oval window niche after stapes surgery.

Type
Research Article
Copyright
Copyright © JLO (1984) Limited 1983

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