Hostname: page-component-586b7cd67f-vdxz6 Total loading time: 0 Render date: 2024-11-23T05:28:57.907Z Has data issue: false hasContentIssue false

Ectopic cervical hamartomatous thymoma showing extensive myoid differentiation

Published online by Cambridge University Press:  29 June 2007

A. Armour
Affiliation:
Department of Histopathology, Leeds General Infirmary, Leeds LS1 3EX
J. M. S. Williamson*
Affiliation:
Department of Pathology, St James's Hospital, Beckett Street, Leeds LS7 9TF
*
Dr. J. M. S. Williamson, Department of Pathology, St James's Hospital, Beckett Street, Leeds LS7 9TF

Abstract

Ectopic ‘hamartomatous’ thymoma is a rare benign neoplasm. These tumours are found in the neck and are thought to be part of a spectrum of ectopic cervical thymic neoplasia. The clinical and histological features are discussed and the literature is reviewed. An attempt is made to explain in embryological terms why such lesions appear to occur more commonly on the left side.

Type
Pathology in Focus
Copyright
Copyright © JLO (1984) Limited 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Al-Shihabi, B. M., Jackson, J. McG. (1982) Cervical thymic cyst. Case report. Journal of Laryngology and Otology, 96: 181189.CrossRefGoogle Scholar
Chan, J. K. C, Rosai, J. (1991) Tumours of the neck showing thymic or related branchial pouch differentiation. A unifying concept. Human Pathology, 22: 349367.CrossRefGoogle ScholarPubMed
Fetsch, J. F., Weiss, S. W. (1990) Ectopic hamartomatous thymoma. Clinicopathological, immunohistochemical and histogenetic considerations in four new cases. Human Pathology, 21: 662668.CrossRefGoogle ScholarPubMed
Geld, H. van derFeltkamp, T. E. W., Oosterhuis, H. J. G. H.(1964) Reactivity of myasthenia gravis serum a-globulin with skeletal muscle and thymus demonstrated by immunofluorescence. Proceedings of the Society of Experimental Biology (New York), 115: 782785.CrossRefGoogle Scholar
Henry, K. (1968) The thymus in rheumatic heart disease. Clinical Experimental Immunology, 3: 509523.Google ScholarPubMed
Kingsbury, B. F. (1939) The question of a lateral thyroid in mammals with special reference to man. American Journal of Anatomy, 65: 333359.CrossRefGoogle Scholar
Makin, C. A. M., Bobrow, L. G., Bodmer, W. F. (1984) Monoclonal antibody to cytokeratin for use in routine histopathology. Journal of Clinical Pathology, 37: 975983.CrossRefGoogle ScholarPubMed
Miyauchi, A., Matsuzuka, E., Kuma, K., Katayama, S., (1992) Piriform sinus fistula and the ultimobranchial body. Histopathology, 20: 221227.CrossRefGoogle ScholarPubMed
Miettinen, M., Salo, J., Virtanen, I. (1986) Testicular stromal tumour. Ultrastructural immune histochemical and gel electrophoretic evidence of epithelial differentiation. Ultrastructural Pathology 10: 515528.CrossRefGoogle Scholar
Moll, R., Franke, W. W, Schuller, D. L. (1982) The catalogue of human cytokeratins. Patterns of expression in normal epithelial tumours and cultural cells. Cell, 31: 1124.CrossRefGoogle Scholar
Moran, C. A., Travis, W. D., Rosada de Christenson, M. (1992) Thymomas presenting as pleural tumours. Report of eight cases. American Journal of Surgical Pathology, 16: 138144.CrossRefGoogle ScholarPubMed
Rosai, J., Levine, G. D. (1976) ‘Tumours of the Thymus’. Atlas of Tumour Pathology, 2nd series, Fascicle 13, Washington, D.C., AFIP.Google Scholar
Rosai, J., Limas, C., Husband, E. M. (1984) Ectopic hamartomatous thymoma. A distinct benign lesion of lower neck. American Journal of Surgical Pathology, 8: 501513.CrossRefGoogle ScholarPubMed
Saeed, I. T, Fletcher, C. D. M. (1990) Ectopic hamartomatous thymoma containing myoid cells. Histopathology, 17: 572574.CrossRefGoogle ScholarPubMed
Valderratna, E., Kahn, L. B., Wind, E. (1983) Extraskeletal osteosarcoma arising in ectopic hamartomatous thymus. Report of a case and review of literature. Cancer, 51: 11321137.3.0.CO;2-Z>CrossRefGoogle Scholar