Hostname: page-component-78c5997874-xbtfd Total loading time: 0 Render date: 2024-11-05T15:53:50.914Z Has data issue: false hasContentIssue false

Dual-probe 24-hour ambulatory pH monitoring for diagnosis of laryngopharyngeal reflux

Published online by Cambridge University Press:  08 March 2006

W.J. Issing
Affiliation:
Department of Otolaryngology, The Freeman Hospital, Newcastle Upon Tyne, UK.
P.D. Karkos
Affiliation:
Department of Otolaryngology, The Freeman Hospital, Newcastle Upon Tyne, UK.
K. Perreas
Affiliation:
Department of Cardiac Surgery, Onassis Cardiac Centre, Athens, Greece.
C. Folwaczny
Affiliation:
Chirurgische Klinik der Ludwig-Maximilians-Universität München, Klinikum Innenstadt, München, Germany.
O. Reichel
Affiliation:
Klinik für Hals-, Nasen- und Ohrenkranke der Ludwig-Maximilians-Universität München, München, Germany.

Abstract

Background: Patients with gastroesophageal reflux disease may suffer from a variety of symptoms from the upper aerodigestive tract. The objective of this study was to determine the impact of dual-probe 24-hr pH monitoring in the diagnosis of reflux-related otolaryngological disorders.

Methods: Twenty-two patients with symptoms such as chronic cough, globus pharyngeus, heartburn,dysphonia and burning sensation of the tongue underwent a complete ear, nose and throat examination, 24-hr dual-probe pH monitoring, and oesophago-gastro-duodenoscopy.

Results: pH monitoring revealed gastroesophageal (distal) reflux in all patients and pharyngeal (proximal) reflux in 21 patients. Treatment consisted of a proton pump inhibitor (esomeprazole). Within 4 weeks 68 per cent of patients had no laryngopharyngeal symptoms; within 8 weeks 95 per cent of patients were symptom-free.

Conclusions: Patients with atypical reflux symptoms such as hoarseness, globus sensation or throat-clearing responded well to anti-reflux treatment.

Type
Research Article
Copyright
© 2004 Royal Society of Medicine Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)