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Drug therapy and tinnitus: the UK experience

Published online by Cambridge University Press:  27 May 2011

J. W. P. Hazell  and
S. M. Wood
J. W. P. Hazell
Affiliation:
(London)
S. M. Wood
Affiliation:
(London)
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Summary

There have been five recent studies of drug treatment in tinnitus in the UK using Class I anti-arrhythmic preparations. We present a new double-blind study of tocainide hydrochloride in severe, unmaskable tinnitus. No significant response is noted in any of the controlled trials to the active ingredient, and more work is needed on diagnostic criteria to see if those who do respond constitute a separate group. There was a surprisingly low incidence of placebo response and the importance of the side effects produced by the drugs in this group is stressed. The finding that three patients with profound hearing losses have had some continued benefit leads to the cautious conclusion that drug responders may be have a central component to their tinnitus.

Type
Session V. Treatment Methods and Results (Chairman: A. Shulman)
Information
The Journal of Laryngology & Otology , Volume 98 , supplement S9: Proceedings of the II International Tinnitus Seminar. New York, 10 and 11 June 1983 , June 1984 , pp. 277 - 280
Copyright
Copyright © JLO (1984) Limited 1984

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References

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