Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-27T07:43:17.942Z Has data issue: false hasContentIssue false

A double-blind clinical trial of hydroxyethylrutosides in Menière's disease

Published online by Cambridge University Press:  29 June 2007

M. Moser
Affiliation:
University Ear, Nose and Throat Clinic, Graz, Austria.
G. Ranacher
Affiliation:
University Ear, Nose and Throat Clinic, Graz, Austria.
T. J. Wilmot*
Affiliation:
Ear, Nose and Throat Department, Tyrone County Hospital, Omagh, Northern Ireland.
G. J. Golden
Affiliation:
Medical Department, Zyma Pharmaceutical Co., Nyon, Switzerland.
*
Mr. T. J. Wilmot, Rathallard, Hospital Road, Omagh, Co. Tyrone BT79 0AN. Northern Ireland.

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Research Article
Copyright
Copyright © JLO (1984) Limited 1984

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Arturson, G. (1972) Effects of O-(ß-hydroxyethyl)-rutosides (HR) on the increased microvascular permeability in experimental skin burns. Acta Chirurgica Scandinavica, 138: 111117.Google Scholar
Bergqvist, D., and Hallböök, T. (1981) A double-blind trial of O-(ß-hydroxyethyl)-rutosides in patients with chronic venous insufficiency. VASA, 10: 253260.Google Scholar
Frew, I. J. C., and Menon, G. N. (1976) Betahistine hydrochloride in Ménière's disease. Postgraduate Medical Journal, 52: 501503.CrossRefGoogle ScholarPubMed
Hammersen, F. (1970) The ultrastructural changes in the microcirculation in experimental oedema: a suitable morphological test-model for the effect of vaso-active drugs. Biorheology, 6: 343351.Google Scholar
Hilton, G. (1980) Effects of HR upon post-burn plasma volume loss in the nonresuscitated dog. Burns, 7: 211214.CrossRefGoogle Scholar
Hladovec, J., and Rossmann, P. (1973) Circulating endothelial cells isolated together with platelets and the experimental modification of their counts in rats. Thrombosis Research, 3: 665674.CrossRefGoogle Scholar
Jongkees, L. B. W. (1980) Some remarks on Ménière's disease. ORL, 42: 19.CrossRefGoogle ScholarPubMed
Klockhoff, I., and Lindblom, U. (1967) Ménière's disease and hydrochlorothiazide (dichlotride)—A critical analysis of symptoms and therapeutic effects. Acta oto-laryngologica, 63: 347365.CrossRefGoogle ScholarPubMed
McEwan, A. J., and McArdle, C. S. (1971) Effect of hydroxyethylrutosides on blood oxygen levels and venous insufficiency symptoms in varicose veins. British Medical Journal, 2: 138141.CrossRefGoogle ScholarPubMed
Prerovsky, I., and Hladovec, J. (1979) Suppression of the desquamating effect of smoking on the human endothelium by hydroxyethylrutosides. Blood Vessels, 16: 239240.Google ScholarPubMed
Roztocil, K., Fischer, A., Novak, P., and Razgova, L. (1971) The effect of O-(ß-hydroxyethyl)-rutosides (HR) on the peripheral circulation in patients with chronic venous insufficiency. European Journal of Clinical Pharmacology, 3, (4): 243246.CrossRefGoogle Scholar
Roztocil, K., Prerovsky, I., and Oliva, I. (1977) The effect ofhydroxyethylrutosides on capillary filtration rate in the lower limb of man. European Journal of Clinical Pharmacology, 11: 435438.CrossRefGoogle ScholarPubMed
Schmid-Schönbein, H., Volger, E., Weiss, J., and Brandhuber, M. (1975) Effect of O-(ß-hydroxyethyl)-rutosides on the microrheology of human blood under defined flow conditions. VASA, 4: 263270.Google Scholar
Thomsen, J., Bech, P., Prytz, S., Vendsborf, P., and Zilstorff, K. (1979) Ménière's disease: lithium treatment (demonstration of placebo effect in a double-blind cross-over trial). Clinical Otolaryngology, 4: 119123.CrossRefGoogle Scholar
Tschopp, M., Pometta, D., and Babel, J. (1970) Diabetic retinopathy: study of the action of O-ß-hydroxyaethyl-rutosides (HR) by retinal fluoresceinography. Diabetologia, 6: 475481.CrossRefGoogle ScholarPubMed
Van Haeringen, N. J., Glasius, E., Ten Cate, J. W., Gerritsen, J., and Van Geet, J. (1973) Effect of O-(ß-hydroxyethyl)-rutoside on red cell and platelet functions in man. Biblioteca Anatomica, 12: 459464.Google Scholar
Wilmot, T. J., and Menon, G. N. (1976) Betahistine in Ménière's disease. Journal of Laryngology and Otology, 90: 833840.CrossRefGoogle ScholarPubMed