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Detection of hepatitis B virus in the cerumen of patients with chronic hepatitis B infection

Published online by Cambridge University Press:  17 October 2013

A Eftekharian ,
H Moghaddasi ,
L Gachkar  and
S S A Amlashi
A Eftekharian*
Affiliation:
Department of Otorhinolaryngology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
H Moghaddasi
Affiliation:
Department of Otorhinolaryngology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
L Gachkar
Affiliation:
Department of Infectious Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran
S S A Amlashi
Affiliation:
Department of Otorhinolaryngology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
*
Address for correspondence: Dr A Eftekharian, Department of Otorhinolaryngology, Loghman Hospital, Kamali Ave, Kargar, 13336-31151 Tehran, Iran Fax: +98,-21-55416170 E-mail: [email protected]
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Abstract

Objective:

To investigate hepatitis B virus DNA in the cerumen of hepatitis B virus infected patients.

Methods:

This study comprised 30 confirmed cases of chronic hepatitis B. Patients' serum samples were examined for hepatitis B surface antigen and antibodies using enzyme immunoassay systems. The presence of hepatitis B virus DNA in cerumen was investigated using a polymerase chain reaction test.

Results:

All of the samples were positive for hepatitis B surface antigen and negative for hepatitis B surface antibodies. Hepatitis virus DNA was detected in two cerumen samples (6.6 per cent of patients).

Conclusion:

Cerumen can be a potential source of transmission of hepatitis B virus.

Keywords

Hepatitis B VirusCerumenChronic Hepatitis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 11 , November 2013 , pp. 1065 - 1066
Copyright
Copyright © JLO (1984) Limited 2013 

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