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Cytomegalovirus ulceration of the oropharynx

Published online by Cambridge University Press:  29 June 2007

P. D. French ,
M. A. Birchall  and
J. R. W. Harris
P. D. French*
Affiliation:
London
M. A. Birchall
Affiliation:
London
J. R. W. Harris
Affiliation:
London
*
Senior Registrar in Genitourinary Medicine, James Pringle House, The Middlesex Hospital, LondonWIN 8AA.
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Abstract

Cytomegalovirus (CMV) is a common opportunistic infection in both iatrogenic and HIV-induced immunosuppression. The usual sites of involvement are the gastro-intestinal tract, retina and lung. We present three cases of CMV ulceration of the oropharynx. All three patients presented with symptoms localized to the oropharynx and in each case the diagnosis was only made on histological examination of ulcer biopsy specimens. The patients all responded well to ganciclovir treatment and at writing none have required maintenance therapy (7–11 months post diagnosis).

Keywords

CytomegalovirusOropharynx
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 105 , Issue 9 , September 1991 , pp. 739 - 742
Copyright
Copyright © JLO (1984) Limited 1991

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References

Cohen, S. G., Greenberg, M. S. (1985) Chronic oral herpes simplex virus infection in immunocompromised patients. Oral Surgery, Oral Medicine, Oral Pathology, 59: 465–471.CrossRefGoogle ScholarPubMed
Corbitt, G., Bailey, A. S., Williams, G. (1990) HIV infection in Manchester. Lancet, 2: 51.CrossRefGoogle Scholar
Jeffries, D. J. (1989) The spectrum of cytomegalovirus infection and its management. Journal of Antimicrobial Chemotherapy, 23 (Suppl E): 1–16.CrossRefGoogle ScholarPubMed
Kanas, R. J., Jensen, J. L., Abrams, A. B., Wuerker, R. B. (1987) Oral mucosal cytomegalovirus as a manifestation of the acquired immune deficiency syndrome. Oral Surgery, Oral Medicine, Oral Pathology, 64: 183–189.CrossRefGoogle ScholarPubMed
Myerson, D., Hackman, R. C., Nelson, J. A., Ward, D. C., McDougal, J. K. (1984) Widespread presence of histologically occult-cytomegalovirus. Human Pathology, 15; 430–439.CrossRefGoogle ScholarPubMed
Peterson, P. K., Balfour, H. H., Marker, S. C., Fryd, D. S., Howard, R. J., Simmons, R. L. (1980) Cytomegalic diseases in renal allograft recipients: a prospective study of the clinical features, risk factors and impact on renal transplantation. Medicine (Baltimore), 59: 283–300.Google Scholar
Pinching, A. J. (1989) Cytomegalovirus infection in the acquired immune deficiency syndrome. Journal Antimicrobial Chemotherapy, 23 (Suppl E): 31–36.Google Scholar
Robson, G. S., Mackay, I. R. (1969) Generalized cytomegalovirus infection in a patient with lupoid hepatitis. Australian Annals of Medicine, 18: 147–150.CrossRefGoogle Scholar
Small, P. M., McPhaul, L. W., Sooy, C. D., Wofsy, C. B., Jacobsen, M. (1989) Cytomegalovirus infection of the laryngeal nerve presenting as hoarseness in patients with the acquired immunodeficiency syndrome. American Journal of Medicine, 86: 108–110.Google Scholar
Takagi, M., Ishikawi, G. (1977) Double viral infection of the mouth in the cancer patient. Bull Tokyo Med Dent Univ, 24: 233–238.Google Scholar
Williams, G., Stretton, T. B., Leonard, J. C. (1960) Cytomegalic inclusion disease and Pneumocystics carinii pneumonia in an adult. Lancet, 2: 951–955.CrossRefGoogle ScholarPubMed