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BIPP induced methaemoglobinaemia

Published online by Cambridge University Press:  29 June 2007

A. Nigam*
Affiliation:
Department of Otlaryngology, Dudley Road Hospital, Birmingham.
J. Ruddy
Affiliation:
Department of Otlaryngology, Dudley Road Hospital, Birmingham.
P. E. Robin
Affiliation:
Department of Otlaryngology, Dudley Road Hospital, Birmingham.
*
A. Nigam F.R.C.S., 6 Rollason Road, Erdington, Birmingham B24 9BJ.

Abstract

Bismuth subnitrate, one of the constituents of BIPP is known to cause methaemoglobinaemia. Ten patients had blood estimations for methaemoglobin levels before and after nasal packing with BIPP impregnated gauze. Only one patient exhibited abnormal levels of methaemoglobin and this was most probably the result of the large quantity of BIPP used. It is unlikely that significant methaemoglobinaemia occurs during the routine use of BIPP in the nose.

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1991

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References

Bunn, F. H. (1987) In Harrison's Principles of Internal Medicine 11th edition, McGraw Hill Book Company Ltd.; New York p 15241525.Google Scholar
Chambers, H., Goldsmith, J. N. (1917) The bacteriological and chemical action of bismuth iodoform paraffin paste. Lancet, 1: 333335.CrossRefGoogle Scholar
Frayling, I. M., Addison, G. M., Chattergee, K., Meakin, G. (1990) Methaemoglobinaemia in children treated with prilocainlignocaine cream. British Medical Journal, 301: 153154.CrossRefGoogle ScholarPubMed
Kearns, G. L., Fiser, D. H. (1988) Metoclopramide-induced methaemoglobinaemia. Paediatrics, 82: 364366.CrossRefGoogle Scholar
Marcus, H., Joffe, J. R. (1949) Nitrate methaemoglobinaemia. New England Journal of Medicine, 240: 599601.CrossRefGoogle Scholar
Nigam, A., Allwood, M. C. (1990) BIPP- How does it work? Clinical Otolaryngology, 15: 173175.CrossRefGoogle ScholarPubMed
Wade, A. (1979) Martindale–The Extra Pharmacopoeia 27th edition, Pharmaceutical Press: London, p. 892893.Google Scholar