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Benign schwannoma in paranasal sinuses: a clinico-pathological study of five cases, emphasising diagnostic difficulties

Published online by Cambridge University Press:  17 August 2007

H Y Sheikh ,
R P Chakravarthy ,
N J Slevin ,
A J Sykes  and
S S Banerjee
H Y Sheikh*
Affiliation:
Department of Clinical Oncology, Christie Hospital NHS Trust, Manchester, UK
R P Chakravarthy
Affiliation:
Department of Histopathology, Christie Hospital NHS Trust, Manchester, UK
N J Slevin
Affiliation:
Department of Clinical Oncology, Christie Hospital NHS Trust, Manchester, UK
A J Sykes
Affiliation:
Department of Clinical Oncology, Christie Hospital NHS Trust, Manchester, UK
S S Banerjee
Affiliation:
Department of Histopathology, Christie Hospital NHS Trust, Manchester, UK
*
Address for correspondence: Dr Hamid Sheikh, Department of Clinical Oncology, Christie Hospital NHS Trust, Wilmslow Road, Withington, Manchester M20 4BX, UK. E-mail: [email protected]
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Abstract

Objectives:

To highlight the difficulty in making a correct diagnosis of benign schwannoma in the paranasal region, to raise awareness of this rare condition, and to suggest the most appropriate treatment.

Method:

Retrieval of cases retrospectively from archives of the histopathology department of a major UK cancer centre with central review of all cases.

Results:

Five cases were identified since 1990 and clinical and pathological features are summarised. Median follow up of patients was 8.1 years. Radiological appearances of local bone invasion and histological features of tumour unencapsulation and hypercellularity could give the mistaken impression of malignant disease and lead to unnecessary over-treatment.

Conclusion:

Central pathological review and clinical awareness is required. Although local recurrence can occur, the prognosis is excellent. The treatment of choice is local excision. Radiotherapy can be considered, but in most cases it would incur unnecessary morbidity.

Keywords

Paranasal Sinus NeoplasmsSchwannoma
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 122 , Issue 6 , June 2008 , pp. 598 - 602
Copyright
Copyright © JLO (1984) Limited 2007

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References

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