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Audiovestibular functions in chronic kidney disease in relation to haemodialysis

Published online by Cambridge University Press:  08 July 2019

T A Gabr ,
M A Kotait  and
H I Okda
T A Gabr*
Affiliation:
Audiovestibular Unit, Otolaryngology Head and Neck Surgery Department, Faculty of Medicine, Kafrelsheikh University, Egypt
M A Kotait
Affiliation:
Audiovestibular Unit, Otolaryngology Head and Neck Surgery Department, Faculty of Medicine, Tanta University, Egypt
H I Okda
Affiliation:
Nephrology Unit, Internal Medicine Department, Faculty of Medicine, Tanta University, Egypt
*
Author for correspondence: Dr Takwa A Gabr, Audiovestibular Unit, Otolaryngology Head and Neck Surgery Department, Faculty of Medicine, Kafrelsheikh University Hospital, Elgeesh Street, Kafrelsheikh, Egypt 33516 E-mail: [email protected] Fax: +2 0473 214 998
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Abstract

Background

Several studies have reported that the audiovestibular system is affected in patients with chronic kidney disease.

Objective

This study aimed to investigate how the audiovestibular system is affected in patients with various stages of chronic kidney disease.

Methods

Sixty participants were divided into three groups: group 1 – controls; group 2 – chronic kidney disease patients receiving conservative treatment; and group 3 – chronic kidney disease patients undergoing regular haemodialysis. Assessments included: standard and high-frequency audiometry and otoacoustic emissions testing, oculomotor tests, and combined vestibular-evoked myogenic potentials testing.

Results

Fifty per cent of group 2 and 60 per cent of group 3 had bilateral sensorineural hearing loss. High-frequency pure tone audiometry showed reduced detectability and higher thresholds at 12 kHz and 16 kHz in patients than in controls. Otoacoustic emissions, tracking, optokinetic and combined vestibular-evoked myogenic potential tests showed abnormal results in chronic kidney disease cases.

Conclusion

Both the auditory and vestibular pathways are affected in different stages of chronic kidney disease. High-frequency pure tone audiometry, otoacoustic emissions and combined vestibular-evoked myogenic potentials could be performed routinely in patients with chronic kidney disease, regardless of the disease stage.

Keywords

Chronic Kidney DiseasesDialysisRenalVestibular Function TestsVestibular Evoked Myogenic Potentials
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 133 , Issue 7 , July 2019 , pp. 592 - 599
Copyright
Copyright © JLO (1984) Limited, 2019 

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Footnotes

Dr T A Gabr takes responsibility for the integrity of the content of the paper

References

1Peyvandi, A, Roozbahany, NA. Hearing loss in chronic renal failure patient undergoing hemodialysis. Indian J Otolaryngol Head Neck Surg 2013;65(suppl 3):537–40Google Scholar
2National Kidney Foundation. K/DOQI clinical practice guidelines for chronic disease: evaluation, classification and stratification. Am J Kidney Dis 2002;39(2 suppl 2):S1–266Google Scholar
3Quick, CA, Fish, A, Brown, C. The relationship between cochlea and kidney. Laryngoscope 1973;83:1469–82Google Scholar
4Gatland, D, Tucker, B, Chalstrey, S, Keene, M, Baker, L. Hearing loss in chronic renal failure--hearing threshold changes following haemodialysis. J R Soc Med 1991;84:587–9Google Scholar
5Yassin, A, Badry, A, Fatt-Hi, A. The relationship between electrolyte balance and cochlear disturbances in cases of renal failure. J Laryngol Otol 1970;84:429–35Google Scholar
6Bergstrom, L, Jenkins, P, Sando, I, English, GM. Hearing loss in renal disease: clinical and pathological studies. Ann Otol Rhinol Laryngol 1973;82:555–76Google Scholar
7Adler, D, Ritz, E. Terminal renal failure and hearing loss. Arch Otorhinolaryngol 1982;235:587–90Google Scholar
8Thodi, C, Thodis, E, Danielides, V, Pasadakis, P, Vargemezis, V. Hearing in renal failure. Nephrol Dial Transplant 2006;21:3023–30Google Scholar
9Soriano, S, Ojeda, R, Rodríguez, M, Almadén, Y, Rodríguez, M, Martín-Malo, A et al. The effect of phosphate binders, calcium and lanthanum carbonate on FGF23 levels in chronic kidney disease patients. Clin Nephrol 2013;80:17–22Google Scholar
10Jung, DJ, Lee, KY, Do, JY, Kang, SH. Chronic kidney disease as a risk factor for vestibular dysfunction. Postgrad Med 2017;129:649–5210.1080/00325481.2017.1338493Google Scholar
11Chou, CH, Wang, SJ, Young, YH. Feasibility of the simultaneous ocular and cervical vestibular-evoked myogenic potentials in unilateral vestibular hypofunction. Clin Neurophysiol 2009;120:1699–705Google Scholar
12Dawson-Saunders, B, Trapp, R, eds. Basic and Clinical Biostatistics, 3rd edn. New York: Lange Medical Books/McGraw Hill, 2001Google Scholar
13Cabrera, SS. Definition, classification of stages, and prevalence of chronic kidney disease. Guidelines for early detection. Risk factors for chronic kidney disease [in Spanish]. Nefrologia 2004;24:27–34Google Scholar
14Mitschke, H, Schmidt, P, Zazgorlik, J, Kopsa, H, Pils, P. Effect of renal transplantation on uraemic deafness; a long-term study. Audiology 1977;16:530–4Google Scholar
15Nikolopoulos, TP, Kandiloros, DC, Segas, SV, Nomicos, PN, Ferekidis, EA, Michelis, KE et al. Auditory function in young patients with chronic renal failure. Clin Otolaryngol 1997;22:222–5Google Scholar
16Lopez, PS, da Silva, CDP, Martin, LC, Montovania, JC. Could the type of treatment for chronic kidney disease affect the auditory system? Braz J Otorhinolaryngol 2014;80:54–9Google Scholar
17Samir, M, Riad, H, Mahgoub, M, Awad, Z, Kamal, N. Transient otoacoustic emissions in children with chronic renal failure. Clin Otolaryngol 1998;23:87–9010.1046/j.1365-2273.1998.00117.xGoogle Scholar
18Pandey, S, Gore, G, Valame, D, Mehta, K. Audiometric profile in patients with chronic renal failure. J Otolaryngol Head Neck Surg 2011;40:131–6Google Scholar
19Ozturan, O, Lam, S. The effect of hemodialysis on hearing using pure-tone audiometry and distortion-product otoacoustic emissions. ORL J Otorhinolaryngol Relat Spec 1998;60:303–13Google Scholar
20Grunwald, JE, Alexander, J, Maguire, M. Prevalence of ocular fundus pathology in patients with chronic kidney disease. Clin J Am Soc Nephrol 2010;5:867–73Google Scholar
21Murofushi, T, Shimizu, K, Takegoshi, H, Cheng, PW. Diagnostic value of prolonged latencies in the vestibular evoked myogenic potentials. Arch Otolaryngol Head Neck Surg 2001;127:1069–7210.1001/archotol.127.9.1069Google Scholar
22Sazgar, AA, Ahmadi, F, Akrami, K, Akrami, S. Vestibular evoked myogenic potentials of haemodialysed patients with end stage renal disease. Eur Arch Otorhinolaryngol 2008;265:393–6Google Scholar
23Couloigner, V, Sterkers, O, Ferrary, E. What's new in ion transports in the cochlea? Pflugers Arch 2006;453:11–2210.1007/s00424-006-0103-4Google Scholar