Hostname: page-component-78c5997874-j824f Total loading time: 0 Render date: 2024-11-20T05:41:07.808Z Has data issue: false hasContentIssue false
  • English
  • Français

Audiological, vestibular and radiological abnormalities in Kallman's syndrome

Published online by Cambridge University Press:  29 June 2007

J. Hill ,
C. Elliott  and
I. Colquhoun
J. Hill*
Affiliation:
Department of Otolaryngology, Freeman Hospital.
C. Elliott
Affiliation:
Department of Medical Physics, Freeman Hospital.
I. Colquhoun
Affiliation:
Department of Radiology, Charing Cross Hospital, London.
*
J. Hill, F.R.C.S., Department of Otolaryngology, Freeman Hospital, High Heaton, Newcastle upon Tyne NE7 7DN.
Get access Rights & Permissions [Opens in a new window]

Abstract

Kallman's syndrome is a multifaceted congenital disorder with predominantly endocrine abnormalities. We have characterized the associated mixed hearing loss and identified consistent radiological evidence of abnormal temporal bone anatomy. Abnormal labyrinthine morphology is accompanied by a complete absence of response to vestibular stimulation with caloric or rotational chair testing.

The endocrine abnormalities are correctable and Kallman's syndrome is a diagnosis worthy of consideration when assessing children with congenital hearing loss.

Keywords

Kallman's SyndromeAudiologyRadiology
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 6 , June 1992 , pp. 530 - 534
Copyright
Copyright © JLO (1984) Limited 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bordin, C. W., Ross, G. T, Rifkind, A. B., Cargille, C. M, Lipsett, M. B. (1969) Studies of the pituitary—leydig cell axis in young men with hypogonadotrophic hypogonadism and hyposmia. Journal of Clinical Investigation, 48: 2046–2050.CrossRefGoogle Scholar
Dean, E. M., Griffiths, C. J., Murray, A. (1986) Stability of the human body investigated by sway magnetometry. Journal of Medical Engineering and Technology, 10: 126–130.CrossRefGoogle ScholarPubMed
Fitzgerald, J. E., Elliott, C., Griffiths, C. J., Birchall, J. P., Murray, A. (1991) Measurement of body sway using a two channel magnotometer instrument. Clinical Otolaryngology (in press).Google Scholar
Jones, J. R., Kemman, E. (1976) Olfacto-genital dysplasia in the female. Obstetrics and Gynaecology Annual, 5: 443–466.Google ScholarPubMed
Kallman, F. J., Schoenfeld, W. A., Barrera, S. E. (1944) The genetic aspects of primary eunochism. American Journal of Mental Deficiency, 48: 203–236.Google Scholar
Lieblich, J. M., Rogol, A. D., White, B. J., Rosen, S. W. (1982) Syndrome of anosmia with hypogonadotrophic hypogonadism (Kallman's syndrome). American Journal of Medicine, 23: 506–519.CrossRefGoogle Scholar
Santen, R. J., Paulsen, C. A. (1973) Hypogonadotrophic eunochism. I. Clinical study of the mode of inheritance. Journal of Clinical Endocrinology and Metabolism, 36: 47–54.CrossRefGoogle Scholar
Walsh, P. C., Wilson, J. D., Allan, T. D. (1978) Clinical and endocrinological evaluation of patients with congenital microphallus. Journal of Urology, 120: 90–95.Google Scholar