Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-06T09:44:19.204Z Has data issue: false hasContentIssue false
  • English
  • Français

Use of narrow-band imaging in detection of nasopharyngeal carcinoma

Published online by Cambridge University Press:  02 January 2013

J F Thong ,
D Loke ,
R Karumathil Sivasankarannair  and
P Mok
J F Thong*
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
D Loke
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
R Karumathil Sivasankarannair
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
P Mok
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, Singapore
*
Address for correspondence: Dr Jiun Fong Thong, Department of Otorhinolaryngology-Head and Neck Surgery, Khoo Teck Puat Hospital, 90 Yishun Central, Singapore768828 E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Aim:

To compare narrow-band images of nasopharyngeal carcinoma with those of normal adenoidal tissue.

Method:

Patients with a nasopharyngeal mass were evaluated using both conventional white light and narrow-band light. Biopsies were performed and Epstein–Barr viral serology was tested for all patients.

Results:

Thirty consecutive patients were recruited. Twenty-one patients had normal adenoidal tissue and seven had nasopharyngeal carcinoma. One patient with papillary adenocarcinoma was excluded. The features of narrow-band imaging in normal adenoidal tissue were: (1) a regularly arranged follicular pattern, and (2) each ‘follicle’ comprising a pale centre with surrounding dark periphery. The features of narrow-band imaging in nasopharyngeal carcinoma were: (1) absence of surface patterns (n = 7), and/or (2) ‘reverse’, haphazard follicular pattern comprising a dark brown centre and pale periphery (n = 3).

Conclusion:

Narrow-band imaging of the surface of adenoidal tissue and nasopharyngeal carcinoma appears to identify distinct, characteristic features as described. Narrow-band imaging may be a useful adjunct in differentiating normal adenoidal tissue from malignancy. Further studies are needed to evaluate its diagnostic accuracy.

Keywords

NasopharynxEndoscopyAdenoidsImaging, DiagnosticNasopharyngeal CarcinomaDiagnosis
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 2 , February 2013 , pp. 163 - 169
Copyright
Copyright © JLO (1984) Limited 2013

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Seow, A, Koh, WP, Chia, KS, Shi, L, Lee, HP, Shanmugaratnam, K. Trends and incidences of cancer in Singapore 1968–2002. In: Ministry of Health. Singapore Cancer Registry Report No. 6. Singapore: Ministry of Health, 2004;88–9Google Scholar
2Kumagai, Y, Inoue, H, Nagai, K, Kawano, T, Iwai, T. Magnifying endoscopy, stereoscopic microscopy, and the microvascular architecture of superficial oesophageal carcinoma. Endoscopy 2002;34:369–75CrossRefGoogle Scholar
3East, JE, Tan, EK, Bergman, JJ, Saunders, BP, Tekkis, PP. Meta-analysis: narrow band imaging for lesion characterization in the colon, oesophagus, duodenal ampulla and lung. Aliment Pharmacol Ther 2008;28:854–67CrossRefGoogle ScholarPubMed
4Lin, YC, Wang, WH. Narrow band imaging for detecting early recurrent nasopharyngeal carcinoma. Head Neck 2011;33:591–4CrossRefGoogle ScholarPubMed
5Vlantis, AC, Chan, ABW, Chan, HS, Woo, JKS, Tong, MCF, van Hasselt, CA. Reversal of pale-to-dark nasopharyngeal follicle ratio on narrow-band imaging. Hong Kong Med J 2010;16:307–9Google ScholarPubMed
6Wang, WH, Lin, YC, Chen, WC, Chen, MF, Chen, CC, Lee, KF. Detection of mucosal recurrent nasopharyngeal carcinomas after radiotherapy with narrow-band imaging endoscopy. Int J Radiat Oncol Biol Phys 2012;83:1213–19CrossRefGoogle ScholarPubMed
7Ho, CY, Lee, YL, Chu, PY. Use of narrow band imaging in evaluation of possible nasopharyngeal carcinoma. Am J Rhinol Allergy 2011;25:107–11CrossRefGoogle ScholarPubMed
8Wang, WH, Lin, YC, Lee, KF, Weng, HH. Nasopharyngeal carcinoma detected by narrow-band imaging endoscopy. Oral Oncol 2011;47:736–41CrossRefGoogle ScholarPubMed
9Muto, M, Minashi, K, Yano, T, Saito, Y, Oda, I, Nonaka, S et al. Early detection of superficial squamous cell carcinoma in the head and neck region and esophagus by narrow band imaging: a multicenter randomized controlled trial. J Clin Oncol 2010;28:1566–72CrossRefGoogle ScholarPubMed
10Dekker, E, van den Broek, FJ, Reitsma, JB, Hardwick, JC, Offerhaus, GJ, van Deventer, SJ et al. Narrow-band imaging compared with conventional colonoscopy for the detection of dysplasia in patients with longstanding ulcerative colitis. Endoscopy 2007;39:216–21CrossRefGoogle ScholarPubMed