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Ultrasound core biopsies of neck lumps: an experience from a tertiary head and neck cancer unit

Published online by Cambridge University Press:  16 July 2021

M Adeel*
Affiliation:
Department of ENT, Sheffield, UK
R Jackson
Affiliation:
Department of ENT, Sheffield, UK
T Peachey
Affiliation:
Department of Radiology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Sheffield, UK
N Beasley
Affiliation:
Department of ENT, Sheffield, UK
*
Author for correspondence: Mr Mohammad Adeel, Department of ENT, Bradford Royal Infirmary, Duckworth Lane, Bradford BD9 6RJ, UK E-mail: [email protected]

Abstract

Background

Traditionally, fine needle aspiration cytology was the primary diagnostic investigation for head and neck lumps; however, ultrasound-guided core biopsy offers the advantage of preserving tissue architecture with increased tissue yield. This study reviews the diagnostic utility of ultrasound-guided core biopsy for investigating head and neck lumps.

Methods

Overall, 287 ultrasound-guided core biopsies were reviewed between May 2017 and April 2019 at a single tertiary site for head and neck cancer.

Results

On initial ultrasound-guided core biopsy, a diagnostic sample was obtained in 94.4 per cent of patients and in 83.7 per cent of patients with lymphoma. Where the initial ultrasound-guided core biopsy was non-diagnostic, 50 per cent of samples were diagnostic on repeat ultrasound-guided core biopsy. Overall, five complications were seen related to ultrasound-guided core biopsy, and all were managed conservatively. No cases of disease recurrence were identified at the biopsy site.

Conclusion

Ultrasound-guided core biopsy is a safe procedure with a high diagnostic yield when investigating head and neck lumps. Patients whose ultrasound-guided core biopsies were non-diagnostic should be considered for excisional biopsy over repeat ultrasound-guided core biopsy.

Type
Main Articles
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press

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Footnotes

Mr M Adeel takes responsibility for the integrity of the content of the paper

References

Saha, S, Woodhouse, NR, Gok, G, Ramesar, K, Moody, A, Howlett, DC. Ultrasound guided core biopsy, fine needle aspiration cytology and surgical excision biopsy in the diagnosis of metastatic squamous cell carcinoma in the head and neck: an eleven year experience. Eur J Radiol 2011;80:792–5CrossRefGoogle Scholar
Layfield, LJ, Bentz, JS, Gopez, EV. Immediate on-site interpretation of fine-needle aspiration smears: a cost and compensation analysis. Cancer 2001;93:319–22CrossRefGoogle ScholarPubMed
McNamara, C, Davies, J, Dyer, M, Hoskin, P, Illidge, T, Lyttelton, M et al. Guidelines on the investigation and management of follicular lymphoma. Br J Haematol 2012;156:446–67CrossRefGoogle ScholarPubMed
Lim, CM, They, J, Loh, KS, Chao, SS, Lim, LHY, Tan, LKS. Role of fine-needle aspiration cytology in the evaluation of parotid tumours. ANZ J Surg 2007;77:742–4CrossRefGoogle ScholarPubMed
Salgarelli, AC, Capparè, P, Bellini, P, Collini, M. Usefulness of fine-needle aspiration in parotid diagnostics. Oral Maxillofac Surg 2009;13:185–90CrossRefGoogle ScholarPubMed
Howlett, D, Harper, B, Quante, M, Berresford, A, Morley, M, Grant, J et al. Diagnostic adequacy and accuracy of fine needle aspiration cytology in neck lump assessment: results from a regional cancer network over a one year period. J Laryngol Otol 2007;121:571–9CrossRefGoogle ScholarPubMed
Novoa, E, Gürtler, N, Arnoux, A, Kraft, M. Role of ultrasound-guided core-needle biopsy in the assessment of head and neck lesions: a meta-analysis and systematic review of the literature. Head Neck 2012;34:1497–503CrossRefGoogle ScholarPubMed
Lioe, T, Elliott, H, Allen, D, Spence, R. The role of fine needle aspiration cytology (FNAC) in the investigation of superficial lymphadenopathy; uses and limitations of the technique. Cytopathology 1999;10:291–7CrossRefGoogle ScholarPubMed
Robinson, I, Cozens, N. Does a joint ultrasound guided cytology clinic optimize the cytological evaluation of head and neck masses? Clin Radiol 1999;54:312–16CrossRefGoogle ScholarPubMed
Kleid, S, Millar, HS. The case against open neck biopsy. Aust N Z J Surg 1993;63:678–81CrossRefGoogle ScholarPubMed
Howlett, D, Menezes, L, Bell, D, Ahmed, I, Witcher, T, Bhatti, N et al. Ultrasound-guided core biopsy for the diagnosis of lumps in the neck: results in 82 patients. Br J Oral Maxillofac Surg 2006;44:34–7CrossRefGoogle Scholar
Kraft, M, Gürtler, N, Schmuziger, N, Arnoux, A. Ultrasound-guided core-needle biopsy in the diagnosis of head and neck lesions. J Laryngol Otol 2007;121:895–6CrossRefGoogle Scholar
Screaton, NJ, Berman, LH, Grant, JW. Head and neck lymphadenopathy: evaluation with US-guided cutting-needle biopsy. Radiology 2002;224:7581CrossRefGoogle ScholarPubMed
Kim, HJ, Kim, JS. Ultrasound-guided core needle biopsy in salivary glands: a meta-analysis. Laryngoscope 2018;128:118–25CrossRefGoogle ScholarPubMed
Schmidt, RL, Hall, BJ, Wilson, AR, Layfield, LJ. A systematic review and meta-analysis of the diagnostic accuracy of fine-needle aspiration cytology for parotid gland lesions. Am J Clin Pathol 2011;136:4559CrossRefGoogle ScholarPubMed
Roh, J-L, Lee, Y-W, Kim, J-M. Clinical utility of fine-needle aspiration for diagnosis of head and neck lymphoma. Eur J Surg Oncol 2008;34:817–21CrossRefGoogle ScholarPubMed
Burke, C, Thomas, R, Inglis, C, Baldwin, A, Ramesar, K, Grace, R et al. Ultrasound-guided core biopsy in the diagnosis of lymphoma of the head and neck. A 9 year experience. Br J Radiol 2011;84:727–32CrossRefGoogle Scholar
Pfeiffer, J, Kayser, G, Ridder, GJ. Sonography-assisted cutting needle biopsy in the head and neck for the diagnosis of lymphoma: can it replace lymph node extirpation? Laryngoscope 2009;119:689–95CrossRefGoogle Scholar
Shah, KS, Ethunandan, M. Tumour seeding after fine-needle aspiration and core biopsy of the head and neck-a systematic review. Br J Oral Maxillofac Surg 2016;54:260–5CrossRefGoogle ScholarPubMed