Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-26T04:45:33.513Z Has data issue: false hasContentIssue false
  • English
  • Français

Tubular e-PTFE implants in glottal and neoglottal insufficiency: tolerance and stability in an animal model

Published online by Cambridge University Press:  08 March 2006

Paolo Tamplenizza ,
Fabio Acocella ,
Flaminio Addis  and
Enrico Bolandrini
Paolo Tamplenizza
Affiliation:
Department of Otorhinolaryngology, Ospedale Maggiore Policlincio IRCCS, University of Milan, Italy.
Fabio Acocella
Affiliation:
Department of Otorhinolaryngology, Veterinary Surgical Clinic, University of Milan, Italy.
Flaminio Addis
Affiliation:
Department of Otorhinolaryngology, Veterinary Surgical Clinic, University of Milan, Italy.
Enrico Bolandrini
Affiliation:
Department of Otorhinolaryngology, Ospedale Maggiore Policlincio IRCCS, University of Milan, Italy.
Get access Rights & Permissions [Opens in a new window]

Abstract

The aim of our research is to develop a laryngeal tissue augmentation technique that will be useful in treating glottal and neoglottal insufficiency.

In a previous study the feasibility of insertion of tubular expanded polytetrafluoroethylene (e-PTFE) tissue implants into the larynx of a porcine model was demonstrated. In this paper we report the clinical, endoscopic, computed tomography (CT) and magnetic resonance image (MRI) and histopathological follow-up findings. These results demonstrate host tolerance of the implant over the period of study (six months) with little tissue reactivity to tubular e-PTFE implants in the porcine model. The tubular shape of the implant enhances stabilization by the rapid and complete host tissue penetration of the implant’s interstices, making tubular e-PTFE a potentially useful soft tissue augmentation material for larygneal incompetence.

Keywords

Surgical ProceduresOperativeLarynx
Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 115 , Issue 2 , February 2001 , pp. 106 - 111
Copyright
© Royal Society of Medicine Press Limited 2001

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)