Hostname: page-component-586b7cd67f-gb8f7 Total loading time: 0 Render date: 2024-11-26T19:10:19.452Z Has data issue: false hasContentIssue false
  • English
  • Français

Triple manifestation of extramedullary plasmacytoma in the upper airway: an unusual clinical entity

Published online by Cambridge University Press:  17 June 2011

I Morariu ,
P Burns ,
P Roche  and
S Hone
I Morariu*
Affiliation:
Department of Otolaryngology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland
P Burns
Affiliation:
Department of Otolaryngology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland
P Roche
Affiliation:
Department of Otolaryngology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland
S Hone
Affiliation:
Department of Otolaryngology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland
*
Address for correspondence: Dr Iuliana Morariu, ENT Department, Royal Victoria Eye and Ear Hospital, Adelaide Road, Dublin 2, Ireland E-mail: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective:

We report an extremely rare case of extramedullary plasmacytoma.

Method:

Case report and review of the English-literature concerning extramedullary plasmacytoma and multiple myeloma.

Result:

We present an unusual case of multiple extramedullary plasmacytomas, which, over a protracted course of 30 years, presented on different occasions at three separate sites in the head and neck. The patient was managed surgically on all occasions, and was disease-free at the time of writing.

Conclusion:

Following review of the literature, we believe this to be the only case with this extremely unusual presentation. This case is noteworthy, not only because of the rarity of extramedullary plasmacytoma, but also because it highlights a number of important clinical issues. The diagnosis and management of extramedullary plasmacytoma require close cooperation between multiple disciplines.

Keywords

PlasmacytomaLarynxTongueNasopharynx
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 9 , September 2011 , pp. 970 - 972
Copyright
Copyright © JLO (1984) Limited 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1Alexiou, C, Kau, RJ, Dietzfelbinger, H. Extramedullary plasmacytoma: tumor occurrence and therapeutic concepts. Cancer 1999;85;2305–14Google Scholar
2Dimopoulos, MA, Kiamouris, C, Moulopoulos, LA. Solitary plasmacytoma of bone and extramedullary plasmacytoma. Hematol Oncol Clin North Am 1999;13:1249–57Google Scholar
3Gormley, PK, Primrose, WJ, Bharucha, H. Subglottic plasmacytoma of the larynx: an acute presentation. J Laryngol Otol 1985;99:925–9Google Scholar
4Loh, HS. A retrospective evaluation of 23 reported cases of solitary plasmacytoma of the mandible, with an additional case report. Br J Oral Maxillofacial Surg 1984;22:216–24Google Scholar
5Galieni, P, Cavo, M, Pulsoni, A. Clinical outcome of extramedullary plasmacytoma. Haematologica 2000;85:47–51Google Scholar
6Waldron, J, Mitchell, DB. Unusual presentations of extramedullary plasmacytoma in the head and neck. J Laryngol Otol 1988;102:102–4Google Scholar
7Kapadia, SB, Desai, U, Cheng, VS. Extramedullary plasmacytoma of the head and neck. A clinicopathologic study of 20 cases. Medicine 1982;61:317–29Google Scholar
8Batsakis, JG. Plasma cell tumors of the head and neck. Ann Otol Rhinol Laryngol 1992;92:311–13Google Scholar
9Malpas, JS, Bergsagel, DE, Kyle, RA. Myeloma: Biology and Management. New York: Oxford University Press, 1995Google Scholar
10Mendenhall, CH, Thar, TL, Million, RR. Solitary plasmacytoma of bone and soft tissue. Int J Radiat Oncol Biol Phys 1980;6:1497–501Google Scholar
11Abemayor, E, Canalis, RF, Greenberg, P, Wortham, DG, Rowland, JP, Sun, NC. Plasma cell tumors of the head and neck. J Otolaryngology 1988;17:376–81Google Scholar
12Bjelkenkrantz, K, Lundgren, J, Olofsson, J. Extramedullary plasmacytoma of the larynx. J Otolaryngol 1981;10:28–34Google Scholar
13Hussong, JW, Perkins, SL, Schnitzer, B. Extramedullary plasmacytoma. A form of marginal zone cell lymphoma? Am J Clin Pathol 1999;1:111–16Google Scholar
14Kyle, RA. Monoclonal gammopathy of undetermined significance and solitary plasmacytoma. Implications for progression to overt multiple myeloma. Hematol Oncol Clin North Am 1997;11: 71–87Google Scholar
15Hardwood, AR, Cummings, BJ, Fitzpatrick, PJ. Radiotherapy for unusual tumors of the head and neck. J Otolaryngol 1984;13:391–4Google Scholar
16Gaffney, CC, Dawes, PJ, Jackson, D. Plasmacytoma of the head and neck. Clin Radiol 1987;38:385–8CrossRefGoogle ScholarPubMed
17Bush, SE, Goffinet, DR, Bagshaw, MA. Extramedullary plasmacytoma of the head and neck. Radiology 1981;140:801–5CrossRefGoogle ScholarPubMed
18Kost, KM. Plasmacytomas of the larynx. J Otolaryngol 1990;19:141–6Google Scholar
19Wax, MK, Yun, KJ, Omar, RA. Extramedullary plasmacytoma of the head and neck. Otolaryngol Head Neck Surg 1993;109:877–85Google Scholar
20Knowling, MA, Harwood, AR, Bergsagel, DE. Comparison of extramedullary plasmacytomas with solitary and multiple plasma cell tumors of bone. J Clin Oncol 1983;1:255–62Google Scholar
21Soutar, R, Lucraft, H, Jackson, G. Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. Clin Oncol 2004;16:405–13Google Scholar