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Topical aminoglycosides in the management of active mucosal chronic suppurative otitis media

Published online by Cambridge University Press:  29 June 2007

J. L. Lancaster ,
Z. G. G. Makura ,
G. Porter  and
M. McCormick
J. L. Lancaster*
Affiliation:
Department of Otolaryngology, The Royal Liverpool University Hospital, Liverpool, UK.
Z. G. G. Makura
Affiliation:
Department of Otolaryngology, The Royal Liverpool University Hospital, Liverpool, UK.
G. Porter
Affiliation:
Department of Otolaryngology, The Royal Liverpool University Hospital, Liverpool, UK.
M. McCormick
Affiliation:
Department of Otolaryngology, The Royal Liverpool University Hospital, Liverpool, UK.
*
Address for correspondence: Mr Jeffrey L. Lancaster, Department of Otolaryngology, The Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP.
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Abstract

Debate has currently re-emerged following a renewed warning issued from the Committee on the Safety of Medicines (CSM) regarding the relative risk of ototoxicity from the use of aminoglycoside-containing drops in patients with tympanic membrane perforations. We present the findings of a survey of ENT consultants, questioning their views and current practice, and we add to the debate by means of a review and discussion of the literature.

Keywords

Otitis mediasuppurativeTherapyToxicity
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 113 , Issue 1 , January 1999 , pp. 10 - 12
Copyright
Copyright © JLO (1984) Limited 1999

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