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Tinnitus in Menière's disease: response to titration Streptomycin therapy

Published online by Cambridge University Press:  27 May 2011

Malcolm D. Graham ,
Robert T. Sataloff  and
John L. Kemink
Malcolm D. Graham
Affiliation:
(Ann Arbor, Michigan)
Robert T. Sataloff
Affiliation:
(Philadelphia, Pennsylvania)
John L. Kemink
Affiliation:
(Ann Arbor, Michigan)
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Abstract

Eight patients with bilateral Menière's disease are reported in whom intramuscular Streptomycin Sulfate (ISS) dosage was titrated in an attempt to alleviate disabling vertigo and hearing loss.

It appears possible to eliminate the vertiginous episodes, preserve or improve hearing, avoid ataxia and oscillopsia, and lessen tinnitus in most of these individuals.

At the present time, we consider this treatment regimen our first choice of therapy in people with bilateral active Menière's disease or in patients whose only hearing ear is actively fluctuating and in whom associated disabling vertigo is present.

Type
Session V. Treatment Methods and Results (Chairman: A. Shulman)
Information
The Journal of Laryngology & Otology , Volume 98 , supplement S9: Proceedings of the II International Tinnitus Seminar. New York, 10 and 11 June 1983 , June 1984 , pp. 281 - 286
Copyright
Copyright © JLO (1984) Limited 1984

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References

1.Fowler, E. P. (1948) Streptomycin treatment for vertigo. Transactions of the American Academy of Ophthalmology and Otolaryngology, 52: 293–301.Google ScholarPubMed
2.Graybiel, A. and Schuknecht, H. F. (1967) Streptomycin Sulfate in the management of Menière's disease. Archives of Otolaryngology, 85: 156–170.CrossRefGoogle Scholar
3.Hamberger, C. A., Hyden, H. and Koch, H. (1949) Streptomycin bei der Menierschen Krankheit. Archf Ohren Nasen-u Kehlkophheilkunde, 155: 667–682.CrossRefGoogle Scholar
4.Hawkins, J. (1946) Quoted in Fowler, E. P. Streptomycin treatment for vertigo. Transactions of the American Academy of Ophthalmology and Otolaryngology, 52: 293–301.Google Scholar
5.Hinshaw, H. S. and Feldman, W. H. (1945) Streptomycin treatment of clinical tuberculosis: a preliminary report. Proceedings of the Staff Meetings of the Mayo Clinic, 20: 313–318.Google Scholar
6.Ruedi, L. (1951) Therapeutic and toxic effects of streptomycin in otology. Laryngoscope, 61: 613–636.CrossRefGoogle ScholarPubMed
7.Schatz, A., Bugie, E. and Waksman, S. A. (1944) A substance exhibiting antibiotic activity gram-positive and gram-negative bacteria. Proceedings of the Society for Experimental Biology and Medicine, 55: 66–69.Google Scholar
8.Schuknecht, H. F. (1956) Ablation therapy for the relief of Menière's disease. Laryngoscope, 66: 859–870.CrossRefGoogle ScholarPubMed
9.Schuknecht, H. F. (1957) Ablation therapy for the relief of Menière's disease. Acta Otolaryngologica (Stockholm), Supplement 132: 14–42.Google Scholar
10.Singleton, E. F. and Schuknecht, H. F. (1968) Streptomycin sulfate in the management of Menière's disease. Otolaryngologic Clinics of North America, 1: 531–539.CrossRefGoogle Scholar
11.VanDeinse, J. F. Deinse, J. F. (1949) Medical treatment for Menière's disease. Nederlandsch Tij schrift Voor Genees-kunde, Haarlem 3, 31: 2619–2627.Google Scholar
12.Wilson, W. R. and Schuknecht, H. F. (1980) Update on the use of Streptomycin therapy for Menière's disease. American Journal of Otology, 2: 108–111.Google ScholarPubMed