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Soft tissue head and neck sarcoma: experience of a tertiary referral centre over a 15-year period

Published online by Cambridge University Press:  29 November 2019

L Harrison ,
T McCulloch  and
N Beasley
L Harrison*
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, Oxford University Hospitals, UK
T McCulloch
Affiliation:
Department of Histopathology, University Hospital, Nottingham, UK
N Beasley
Affiliation:
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital, Nottingham, UK
*
Author for correspondence: Ms Laura Harrison, Department of Otorhinolaryngology, Head and Neck Surgery, Oxford University Hospitals, Oxford, UK E-mail: [email protected]
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Abstract

Background

Head and neck soft tissue sarcoma is uncommon. It is both histologically and clinically heterogeneous, ranging from an indolent, locally destructive tumour, to a locally aggressive neoplasm with metastatic potential.

Methods

A retrospective review was conducted of all adult head and neck soft tissue sarcomas, including cases of malignant soft tissue sarcoma and all intermediate type tumours, diagnosed between 1997 and 2012.

Results

Sixty-eight cases were identified in this series from the sarcoma multidisciplinary team. Seventeen different histological subtypes of sarcoma were identified. Neither age, gender nor tumour size were significant prognostic indicators for survival in this series.

Conclusion

Prognosis is dependent on histological subtype, underscoring the importance of histological classification. Some histological subtypes occur only once or twice in a decade, even within a large regional referral centre. An accumulation of evidence from relatively small case series is key in the long-term development of treatment strategies.

Keywords

Sarcoma, Soft TissuePrognosisSurvivalWorld Health Organization
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 133 , Issue 12 , December 2019 , pp. 1053 - 1058
Copyright
Copyright © JLO (1984) Limited, 2019

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Footnotes

Ms L Harrison takes responsibility for the integrity of the content of the paper

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