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Serum enzymes in head and neck cancer. II Aliesterase

Published online by Cambridge University Press:  29 June 2007

Harbans Lal*
Affiliation:
(Rohtak, India)
H. C. Madan
Affiliation:
(Rohtak, India)
G. S. Kohli
Affiliation:
(Rohtak, India)
S. P. S. Yadav
Affiliation:
(Rohtak, India)
*
Dr. Harbans Lai, Department of Biochemistry, 12/9J, Medical College, Rohtak—124001 (India).

Abstract

Serum aliesterase levels have been estimated in 38 patients with head and neck cancer. The mean value was significantly lower than in controls. The decrease in activity was greater in patients with ulcerative growths and it progressed with advancement in the stage of cancer.

With radiotherapy, a progressive and significant increase in serum aliesterase activity was observed. In patients with non-malignant growths the activity was comparable with that in controls.

Type
Research Article
Copyright
Copyright © JLO (1984) Limited 1987

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References

Bhatia, P. L., Singh, M. M. and Chakaravorty, M. (1979) Enzymatic study in diagnosis of head and neck cancer. Indian Journal of Otolaryngology, 31: 7679.CrossRefGoogle Scholar
Bodansky, O. (1954) Serum hexose isomerase in cancer II. As an index of tumour growth in metastatic carcinoma of breast. Cancer, 7: 12001226.3.0.CO;2-9>CrossRefGoogle Scholar
Boesen, A. M., Hokland, P. and Jensen, O. M. (1984) Acid phosphatase and acid esterase activity in neo-plastic and non-neoplastic lymphoid cells. A semi-quantative evaluation related to immunological marker in 112 cases. Scandinavian Journal of Hema-tology, 32: 313322.CrossRefGoogle Scholar
Clausen, P. P., Hojgaard, K. and Thommesen, N. (1979) The diagnostic value of cytochemical staining for nonspecific esterase in the search for cancer cells in effusions. Acta Pathologica el Microbiologica Scandinavica, 87A: 347352.Google ScholarPubMed
Goel, H., Kohli, G. S. and Lai, H. (1986) Serum phosphohexose isomerase levels in patients with head and neck cancer. Journal of Laryngology and Otology, 100: 581585.CrossRefGoogle ScholarPubMed
Gutman, A. B. (1959) Serum alkaline phosphatase activity in diseases of skeletal and hepatobiliary system. A consideration of the current status. American Journal of Medicine, 27: 875901.CrossRefGoogle ScholarPubMed
Huggins, C. and Lapides, J. (1947) Chromogenic substrates. IV. Acyl esters of p-nitrophenol as substrates for the colorimeteric determination of esterase. The Journal of Biological Chemistry, 170: 467482.CrossRefGoogle Scholar
Sufrin, G., Tritsch, G. L., Mittelman, A. and Murphy, G. P. (1978) Adenosine deaminase activity in patients with carcinoma of the bladder. Journal of Urology 119: 343346.CrossRefGoogle ScholarPubMed
UICC (1978) Report of Committee on TNM classification. Geneva.Google Scholar
Vaid, P., Sharma, D. C. and Shastri, K. D. (1974) A clinicobiochemical study of phosphohexose isomerase, aliesterase and sulfhydral group in 25 normal and 35 cancer suspects. Indian Journal of Cancer, 11: 448456.Google Scholar
Wroblewski, F. and La Due, J. S. (1955) Serum glu-tamic oxaloacetic transaminase activity as an index of liver cell injury from cancer. A preliminary report. Cancer, 8: 11551163.3.0.CO;2-V>CrossRefGoogle Scholar