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Sarcomas of nasal cavity and paranasal sinuses: chondrosarcoma, osteosarcoma and fibrosarcoma

Published online by Cambridge University Press:  29 June 2007

V. Koka ,
R. Vericel ,
E. Lartigau ,
A. Lusinchi  and
G. Schwaab
V. Koka
Affiliation:
Department of Head and Neck Surgery, Institut Gustave Roussy, Paris, France.
R. Vericel
Affiliation:
Department of Head and Neck Surgery, Institut Gustave Roussy, Paris, France.
E. Lartigau
Affiliation:
Department of Head and Neck Surgery, Institut Gustave Roussy, Paris, France.
A. Lusinchi
Affiliation:
Department of Head and Neck Surgery, Institut Gustave Roussy, Paris, France.
G. Schwaab*
Affiliation:
Department of Head and Neck Surgery, Institut Gustave Roussy, Paris, France.
*
Dr G. Schwaab, Département de Chirurgie Cervico-Faciale, Institut Gustave Roussy, Rue Camille Desmoulins, 94805 Villejuif cedex, Paris, France.
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Abstract

Forty-two patients were treated for sarcoma of the nasal cavity and paranasal sinuses at the Institut Gustave Roussy, Paris, between 1960 and 1993. Twelve patients had chondrosarcoma (CS), 14 had osteosarcoma (OS) and 16 had fibrosarcoma (FS). Ten patients had grade I, six grade II and 26 grade HI tumours.

All but 10 patients had surgery for the primary tumour. A significantly increased risk of local failure was associated with the male sex (p <0.01), grade III tumours (p <0.02) and patients excluded from surgery (p <0.04). The overall incidence of local and distant failure was 76 and 12 per cent respectively. Overall survival was 28 per cent at three years and 23 per cent at five years. Eight patients (20 per cent) were alive more than 10 years later. The factors significantly influencing survival were sex (p <0.01), grade (p <0.05) and local failure (p<0.01).

Keywords

Paranasal sinus neoplasmsNasal neoplasmsChondrosarcomaOsteosarcomaFibrosarcomaSurgeryRadiotherapyChemotherapyadjuvantCombined modality therapy
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 108 , Issue 11 , November 1994 , pp. 947 - 953
Copyright
Copyright © JLO (1984) Limited 1994

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References

Arlen, M., Higinbotham, N. L., Huvos, A. G. (1971) Radiationinduced sarcoma of the bone. Cancer 28: 1087–1099.3.0.CO;2-F>CrossRefGoogle Scholar
Batsakis, J. B., Solomon, A. R., Rice, D. H. (1980) The pathology of head and neck tumours: neoplasms of cartilage, bone and notochord. Head and Neck Surgery 3: 43–57.CrossRefGoogle ScholarPubMed
Burkey, B. B., Hoffman, H. f., Baker, S. R., Thornton, A. F. McClatchey (1990) Chondrosarcoma of the head and neck. Laryngoscope 100: 1301–1305.CrossRefGoogle ScholarPubMed
Conley, J., Stout, A. P., Healey, W. V. (1967) Clinico-pathologic analysis of eighty-four patients with an original diagnosis of fibrosarcoma of the head and neck. American Journal of Surgery 114: 564–569.CrossRefGoogle Scholar
de Fries, H. O., Perlin, E., Leibel, S. A. (1979) Treatment of osteogenic sarcoma of the mandible. Archives of Otolarynqology 105: 358–359.CrossRefGoogle ScholarPubMed
Eilber, F. R., Morton, D. L., Eckardt, J., Grant, T., Weisenburger, T. (1984) Limb salvage for skeletal soft tissue sarcomas: multidisciplinary preoperative therapy. Cancer 53: 2579–2584.3.0.CO;2-V>CrossRefGoogle ScholarPubMed
El-Silimy, O. E., Harvey, L., Bradley, P. J. (1987) Chondrogenic neoplasms of nasal cavity. Journal of Laryngology and Otology 101: 500–505.CrossRefGoogle ScholarPubMed
Evans, H. L., Ayola, A. G., Romsdahl, M. M. (1977) Prognostic factors in chondrosarcoma of bone, a clinicopathologic analysis with emphasis on grading. Cancer 40: 818–831.3.0.CO;2-B>CrossRefGoogle Scholar
Farhood, A. I., Hadju, S. I., Shiu, M. H., Strong, E. W. (1990) Soft tissue sarcomas of the head and neck in adults. American Journal of Surgery 160: 365–369.CrossRefGoogle ScholarPubMed
Feintusch, T. A. (1973) Chondrosarcoma arising in a previously irradiated fibrous dysplasia. Cancer 31: 877–881.3.0.CO;2-U>CrossRefGoogle Scholar
Feun, L. G., Albores-Saavedra, J., Savaraj, N., Fla, M. (1991) Osteogenic sarcoma arising adjacent to a long-standing ameloblasoama. A case report. Oral Surgery, Oral Medicine and Oral Pathology 71: 77–79.CrossRefGoogle ScholarPubMed
Figueiredo, M. T. A., Marques, L. A., Campos-Filho, N. (1988) Soft tissue sarcomas of the head and neck in adults and children: experience at a single Institution and review of the literature. International Journal of Cancer 41: 198–200.CrossRefGoogle Scholar
Finn, D., Goepfert, H., Batsakis, J. (1984) Chondrosarcoma of the head and neck. Laryngoscope 94: 1539–1544.CrossRefGoogle ScholarPubMed
Frankenthaler, R., Ayala, A. G., Hartwick, R. W., Goepfert, H. (1990) Fibrosarcoma of the head and neck. Laryngoscope 100: 799–802.CrossRefGoogle ScholarPubMed
Friedman, M. A., Carter, S. K. (1972) The therapy of osteogenic sarcoma: current status and thoughts for the future. Journal of Surgical Oncology 4: 482–510.CrossRefGoogle ScholarPubMed
Freidman, A. M., Reinman, H. M., Woods, J. E. (1989) Soft-tissue sarcomas of the head and neck. American Journal of Surgery 158: 367–372.CrossRefGoogle Scholar
Fu, Y-S., Pezin, K. H. (1974) Nonepithelial tumours of the nasal cavity, paranasal sinuses, and nasopharynx: a clinicopathologic study. III. Cartilaginous Tumors (chondroma, chondrosarcoma). Cancer 34: 453–463.3.0.CO;2-I>CrossRefGoogle Scholar
Harwood, A. R., Krajbich, J. I., Fornasier, V. L. (1980) Radiotherapy for chondrosarcoma of bone. Cancer 45: 2769–2777.3.0.CO;2-X>CrossRefGoogle ScholarPubMed
Kaplan, E. L., Meijer, P. (1958) Non-parametric estimation from incomplete observations. Journal of the American Statistical Association 53: 457–481.CrossRefGoogle Scholar
Kalifa, C., Razafindrakoto, H., Vassal, G., Contesso, G., Vanel, D., Edeline, V., Valteau, D., Lemerle, J. (1993) Chemotherapy in osteogenic sarcoma: the experience of the paediatric Department of the Gustave Roussy Institute. In Osteosarcoma in Adolescents and Young Adults (Bennett-Humphry, G., ed.), Kluwer Academic Publishers, Boston, pp 347–349.Google Scholar
Lacovara, J., Patterson, K., Reaman, G. H. (1992) Primary nasal chondrosarcoma. The paediatric experience. American Journal of Paediatric HematologylOncology 14 (2): 158–162.CrossRefGoogle Scholar
Link, M., Goorin, A., Miser, A., Green, A., Pratt, C., Belasco, J., Pritchard, J., Baker, A., Kirkpatrick, J., Ayala, A., Shuster, J., Abelsone, H., Simone, J., Vietti, T. (1985) The role of adjuvant chemotherapy in the treatment of osteosarcoma of the extremity; preliminary results of the Multi-Institutional Osteosarcoma Study. Proceedings of the American Society of Clinical Oncology 4: 237.Google Scholar
Malawer, M. M., Link, M. P., Donaldson, L. L. (1989) Sarcoma of bone. In Cancer: Principles and Practice of Oncology (Devita, V. T, Hellman, S., Rosenberg, S. A., eds). J. B. Lippincott, Philadelphia; 1442–1453.Google Scholar
Mandard, A. M., Petiot, J. F, Marnay, J., Mandard, J. C, Chasle, J., de Ranieri, E., Dupin, P., Herlin, P., de Ranieri, J., Tanguy, A., Boulier, N., Abbatucci, J. S. (1989) Prognostic factors in soft tissue sarcomas. A multivariate analysis of 109 cases. Cancer 63: 1437–1451.3.0.CO;2-Q>CrossRefGoogle ScholarPubMed
Mark, R. J., Sercarz, J. A., Tran, L., Dodd, L. G., Selch, M., Calcaterra, T. C. (1991a) Osteogenic sarcoma of the head and neck. The UCLA experience. Archives of Otolaryngology, Head and Neck Surgery 117: 761–766.CrossRefGoogle ScholarPubMed
Mark, R. J., Sercarz, J. A., Tran, L., Selch, M., Calcaterra, T. C. (1991b) Fibrosarcoma of the head and neck. The UCLA experience. Archives of Otolaryngology, Head and Neck Surgery 117: 396–401.CrossRefGoogle ScholarPubMed
McKenna, W. G., Barnes, M. M., Kinsella, T. J., Rosenberg, S. A., Lack, E. E., Glastein, E. (1987) Combined modality treatment of adult soft tissue sarcomas of the head and neck. International Journal of Radiation Oncology, Biology and Physics 13: 1127–1133.CrossRefGoogle ScholarPubMed
Mindell, E. R., Shols, N. K., Webster, J. H. (1977) Post-radiation sarcoma of bone and soft tissues. Orthopaedic Clinics of North America 8: 821–834.CrossRefGoogle Scholar
Peto, R., Pike, M. C. (1973) Conservatism in the approximation Σ (O-E)2/E in the log-rank test for survival data or tumor incidence data. Biometrics 29: 579–584.CrossRefGoogle ScholarPubMed
Rosen, G., Caparros, B., Huvos, A. G., Kosloff, C., Nirenberg, A., Cacavio, A., Marcove, R. C, Lane, J. M., Mehta, B., Urban, C. (1982) Preoperative chemotherapy for osteogenic sarcoma: selection of postoperative chemotherapy based on the response of the primary tumour to preoperative chemotherapy. Cancer 49: 1221–1230.3.0.CO;2-E>CrossRefGoogle ScholarPubMed
Simon, M. A., Achliman, M. A., Thomas, N., Mankin, H. J. (1986) Limb salvage treatment versus amputation for osteosarcoma of the distal end of the femur. Journal of Bone and Joint Surgery. American volume (Boston) 68: 1331–1337.Google Scholar
Swain, R. E., Sessions, D. G., Ogura, J. H. (1974) Fibrosarcoma of the head and neck: a clinical analysis of fifty cases. Annals of Otolaryngology 83: 439–444.Google Scholar
UICC (1987) International Union against Cancer. In TNM Classification of Malignant Tumours, 4th Edition (Hermanek, P., Sobin, L. H., eds). Springer-Verlag, Heidelberg.CrossRefGoogle Scholar
Vener, J., Rice, D. H., Newman, A. N. (1984). Osteosarcoma and chondrosarcoma of the head and neck. Laryngoscope 94: 240–242.CrossRefGoogle ScholarPubMed
Wanebo, H. J., Koness, J. R., MacFarlane, J. K., Elber, F. R., Byers, R. M., Elias, G., Spiro, R. H. (1992) Head and neck sarcoma: report of the head and neck sarcoma registry. Head and Neck Surgery 14: 1–7.Google ScholarPubMed
Weber, R., Benjamin, R., Peters, L. (1986) Soft tissue sarcomas of the head and neck in adolescents and adults. American Journal of Surgery 152: 386–392.CrossRefGoogle ScholarPubMed