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Rhabdomyosarcoma of the maxillary sinus

A case report

Published online by Cambridge University Press:  29 June 2007

M. Suzuki ,
Y. Kobayashi ,
Y. Harada ,
T. Kyo ,
H. Dohy ,
A. Kuramoto  and
R. Etoh
M. Suzuki*
Affiliation:
Department of Otolaryngology.
Y. Kobayashi
Affiliation:
Department of Otolaryngology.
Y. Harada
Affiliation:
Department of Otolaryngology.
T. Kyo
Affiliation:
Department of Internal Medicine.
H. Dohy
Affiliation:
Department of Internal Medicine.
A. Kuramoto
Affiliation:
Department of Internal Medicine.
R. Etoh
Affiliation:
Second Department of Pathology, Hiroshima University, School of Medicine, Hiroshima, Japan.
*
Department of Otolaryngology, Hiroshima University, School of Medicine, 1-2-3 Kasumi, Minami-ku, Hiroshima, Japan734.
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Abstract

A rare case of adult rhabdomyosarcoma originating from the left maxillary sinus is reported. A 22-year-old Japanese woman was referred to the Department of Otolaryngology, Hiroshima University, for investigation of the primary source of a metastatic tumor in the bone marrow. An X-ray of the sinuses revealed a tumor in the left maxillary sinus with extension into the nasal cavity, ethmoidal and sphenoidal sinuses. The patient was managed with a chemotherapeutic regimen consisting of high-dose methotrexate, adriamycin, vincristine, cyclophosphamide and prednisolone. After three courses of this chemotherapy, the tumor had decreased in size by about 90 per cent, as indicated by X-rays. The remaining tumor was removed by an extended Denker's operation. Following the surgery another seven courses of chemotherapy were given and during the eight months following the operation the patient has been free from any local recurrence.

Type
Clinical records
Information
The Journal of Laryngology & Otology , Volume 98 , Issue 4 , April 1984 , pp. 405 - 415
Copyright
Copyright © JLO (1984) Limited 1984

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References

Dito, W. R., and Batsakis, J. G. (1962) Rhabdomyosarcoma of the head and neck. Archives of Surgery, 84: 582–588.CrossRefGoogle ScholarPubMed
Donaldson, S. S., Castro, J. R., Wilbur, J. R., and Jesse, R. H. (1973) Rhabdomyosarcoma of head and neck in children. Cancer, 31: 26–35.3.0.CO;2-A>CrossRefGoogle ScholarPubMed
Enzinger, F. M., and Weiss, S. W. (1983) Rhabdomyosarcoma. In Soft Tissue Tumors, Chapter 15, pp. 338–373. The C. V. Mosby Company, St Louis.Google Scholar
Frel, E., Blum, R. H., Pitman, S. W., Kirkwood, J. M., Henderson, I. C., Skarin, A. X., Mayer, R. J., Bast, R. C., Garnick, M. B., Parker, L. M., and Canellos, G. P. (1980) High dose methotrexate with leucovorin rescue. The American Journal of Medicine, 68: 370–375.Google Scholar
Friedmann, I., and Osborn, D. A. (1982) Pathology ofGranulomas and Neoplasms of the Nose and Paranasal Sinuses, Chapter 23, p. 292. Blackwell, Oxford.Google Scholar
Fu, Y., and Perzin, K. H. (1976) Nonepithelial tumors of the nasal cavity, paranasal sinuses, and nasopharynx. Cancer, 37: 364–376.3.0.CO;2-Y>CrossRefGoogle ScholarPubMed
Fujimoto, T., and Sasaki, K. (1979) Pharmacokinetics of high dose methotrexate in serum and cerebrospinal fluid. Cancer and Chemotherapy, 6: Supplement II, 279–285.Google Scholar
Fujimoto, T., Sasaki, K., and Goya, N. (1978) High-Dose Methotrexate therapy of childhood cancer—observations relating to clinical toxicity. Journal of Japan Society of Cancer Therapy, 13: 118–125.Google ScholarPubMed
Ghavimi, F., Exelby, P. R., D'Angio, G. J., Cham, W., Lieberman, P. H., Tan, C., Miké, V., and Murphy, M. L. (1975) Multidisciplinary treatment of embryonal rhabdomyosarcoma in children. Cancer, 35: 677–686.3.0.CO;2-Y>CrossRefGoogle ScholarPubMed
Jaffe, N., Frei, E. III, and Watts, H. (1978) High-dose methotrexate in osteogenic sarcoma: A 5-year experience. Cancer Treatment Report, 62: 259–264.Google ScholarPubMed
Koike, S., and Shizuku, S. (1979) Practica Otologica (Kyoto), 63: 539–545.Google Scholar
Okamura, J., and Sutow, W. W. (1977) Rhabdomyosarcoma in children—Clinical features of 161 cases. The Journal of Pediatric Practice, 40: 561–568.Google Scholar
Pratt, C. B., Huster, H. O., Fleming, I. D., and Pinkel, D. (1972) Coordinated treatment of childhood rhabdomyosarcoma with surgery, radiotherapy and combination chemotherapy. Cancer Research, 32: 606–610.Google ScholarPubMed
Sasaki, K, and Fujimoto, T. (1979) Massive dose methotrexate with citrovorum factor rescue: MTX- pharmacokinetics, excretion pattern, and techniques for safety administration. Journal of Japan Society of Cancer Therapy, 14: 988–996.Google ScholarPubMed
Sutow, W. W., Sullivan, M. P., Reed, H. L., Taylor, H. G., and Griffith, K. M. (1970) Prognosis in childhood rhabdomyosarcoma. Cancer, 25: 1384–1390.3.0.CO;2-T>CrossRefGoogle ScholarPubMed
Yoshimi, M., Kawai, H., Sakuma, T., Ushigome, S., Kirino, Y., and Shinagawa, T. (1972) Rhabdomyosarcoma in otolaryngological field. Oto-rhino-laryngology (Tokyo), 15: 783–792.Google Scholar