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Prospective study of the use of vasoconstrictor and saline in septal surgery for infiltration

Published online by Cambridge University Press:  29 June 2007

I Vanniasegaram*
Affiliation:
(Hull)
*
I. Vanniasegaram, F.R.C.S.Ed., MaxRayne House, 109 Camden Road, London NW1 9HA.

Abstract

Vasoconstrictor agents are often used to reduce bleeding and hence improvethe operative field in surgery. These agents are potentially dangerous. A trial was undertaken to compare the use of adrenaline 1:80,000 with saline alone as an infiltrating agent in 30 consecutive patients undergoing septoplasty under general anaesthesia. This study, based on a small number of patients can draw no firm conclusions. There are no really dramatic differences between 1:80,000 adrenaline and saline, in terms of blood loss, operative time and the condition of the operative field between the two groups. However, there is a possibility that there are substantial differences, which, because of the variability of these outcomes, could not be detected in a study as small as this. It is recommended that a randomized trial involving patients is used to answer the question.

Keywords

Type
Main Articles
Copyright
Copyright © JLO (1984) Limited 1991

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