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Principles of gene therapy: prospects for the treatment of head and neck cancer

Published online by Cambridge University Press:  29 June 2007

Nicola K. Green  and
Iain A. McNeish
Nicola K. Green
Affiliation:
Author for correspondence.
Iain A. McNeish
Affiliation:
CRC Institute for Cancer Studies, University of Birmingham, Edgbaston, Birmingham B15 2TA.
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Abstract

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Type
Molecular Biology Series
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 10 , October 1998 , pp. 913 - 920
Copyright
Copyright © JLO (1984) Limited 1998

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References

Anlezark, G. M., Melton, R. G., Sherwood, R. F., Coles, B., Friedlos, F., Knox, R. J. (1992) The bioactivation of CB 1954. I. Purification and properties of a nitroreductase enzyme from Escherichia coli – a potential enzyme for antibody directed enzyme therapy (ADEPT). Biochemical Pharmacology 44: 2289–2295.CrossRefGoogle ScholarPubMed
Bischoff, J. R., Kirn, D. H., Williams, A., Heise, C, Horn, S., Muna, M., Ng, L., Nye, J. A., Sampson-Johannes, A., Fattacy, A., McCormick, F. (1996) An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 274: 373–376.CrossRefGoogle ScholarPubMed
Blaese, R. M., Culver, K. W., Miller, A. D., Carter, C. S., Fleisher, T., Clerici, M., Shearer, G., Chang, L., Chiang, Y., Tolstoshev, P. et al. (1995) T lymphocyte directed gene therapy for ADA SCID: initial results after four years. Science 270: 475–180.CrossRefGoogle Scholar
Blau, H., Khavari, P. (1997) Gene therapy: progress, problems, prospects. Nature Medicine 3: 612–613.CrossRefGoogle Scholar
Bodmer, W. (1994) Cancer genetics. British Medical Bulletin 50 (3): 517–526.CrossRefGoogle ScholarPubMed
Brambilla, E., Gazzeri, S., Moro, D., Caron de Fromentel, C, Gouyer, V., Jacrot, M., Brambilla, C. (1993) Immunohistochemical study of p53 in human lung carcinomas. American Journal of Pathology 143 (1): 199–210.Google ScholarPubMed
Brennand, J., Konecki, D., Caskey, C. (1983) Expression of human and Chinese hamster hypoxanthine-guanine phosphoribosyl transferase cDNA recombinants in cultures Lesch-Nyhan and Chinese hamster fibroblasts. Journal of Biological Chemistry 258: 9593–9596.CrossRefGoogle Scholar
Chang, E. H., Jang, Y. J., Hao, Z., Murphy, G., Rait, A., Fee, W. J. Jr., Sussman, H. H., Ryan, P., Chiang, Y., Pirollo, K. F. (1997) Restoration of the Gl checkpoint and the apoptotic pathway mediated by wild-type p53 sensitizes squamous cell carcinoma of the head and neck to radiotherapy. Archives of Otolaryngology – Head and Neck Surgery 123 (5): 507–512.CrossRefGoogle Scholar
Chong, H., Vile, R. (1996) Replication-competent retrovirus produced by a ‘split-function’ third generation amphotropic packaging cell line. Gene Therapy 3: 624–629.Google ScholarPubMed
Connor, J., Bannerji, R., Saito, S., Heston, W., Fair, W., Gilboa, E. (1993) Regression of bladder tumors in mice treated with interleukin 2 gene-modified tumor cells. Journal of Experimental Medicine 177 (4): 1127–1134.CrossRefGoogle ScholarPubMed
Cosset, F. L., Takeuchi, Y., Battini, J. L., Weiss, R. A., Collins, M. K. (1995) High-titre packaging cells producing recombinant retroviruses resistant to human serum. Journal of Virology 69: 7430–7436.CrossRefGoogle Scholar
Culver, K., Cornetta, K., Morgan, R., Morecki, S., Aebersold, P., Kasid, A., Lotze, M., Rosenberg, S. A., Anderson, W. F., Blaese, R. M. (1991) Lymphocytes as cellular vehicles for gene therapy in mouse and man. Proceedings of the National Academy of Sciences of the United States of America 88(8): 3155–3159.CrossRefGoogle ScholarPubMed
Culver, K. W., Ram, Z., Wallbridge, S., Ishii, H., Oldfield, E. H., Blaese, R. M.In vivo gene transfer with retroviral vector producer cells for treatment of experimental brain tumors. Science 256(5063): 1550–1552.CrossRefGoogle Scholar
Debbas, M., White, F. (1993) Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes and Development 7 (4): 546–554.CrossRefGoogle ScholarPubMed
de Takats, P. G., Kerr, D. J., Poole, C. J., Warren, H. W., McArdie, C. S. (1994) Hepatic artery chemotherapy for metastatic colorectal carcinoma. British Journal of Cancer 69: 372–378.CrossRefGoogle ScholarPubMed
Dillman, R. O. (1994) The clinical experience with interleukin-2 in cancer therapy. Cancer Biotherapy 9: 183–209.CrossRefGoogle ScholarPubMed
Donahue, R. E., Kessler, S. W., Bodine, D., McDonagh, K., Dunbar, C, Goodman, S., Agricola, B., Byrne, E., Raffeld, M., Moen, R. et al. (1992) Helper virus-induced T-cell lymphoma in non-human primates after retroviral mediated gene transfer. Journal of Experimental Medicine 176: 1125–1135.CrossRefGoogle Scholar
Dranoff, G., Jaffee, E., Lazenby, A., Golumbek, P., Levitsky, H., Brose, K., Jackson, V., Hamada, H., Pardoll, D., Mulligan, R. C. (1993) Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific and long-lasting anti-tumor immunity. Proceedings of the National Academy of Sciences of the United States of America 90: 3539–3543.CrossRefGoogle ScholarPubMed
Dranoff, G., Soiffer, R., Lynch, T., Mihm, M., Jung, K., Kolesar, K., Liebster, L., Lam, P., Duda, R., Mentzer, S., Singer, S., Tanabe, K., Johnson, R., Sober, A., Bhan, A., Clift, S., Cohen, L.. Parry, G., Rokovich, J., Richards, L., Drayer, J., Berns, A., Mulligan, R. C. (1997) A phase I study of vaccination with autologous, irradiated melanoma cells engineered to secrete human granulocyte-macrophage colony stimulating factor. Human Gene Therapy 8:111–123.CrossRefGoogle ScholarPubMed
Gansbacher, B., Zier, K., Daniels, B., Cronin, K., Bannerji, R.. Gilboa, F. (1990) Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity. Journal of Experimental Medicine 172(4): 1217–1224.CrossRefGoogle ScholarPubMed
Goebel, F. A., Davidson, B. L., Zabner, J., Graham, S. M., Kern, J. A. (1996) Adenovirus-mediated gene therapy for head and neck squamous cell carcinomas. Annals of Otology, Rhinology and Laryngology 105(7): 562–567.Google ScholarPubMed
Goldman, C. K., Rogers, B. E.. Douglas, J. T., Sosnowski, B. A., Ying, W., Siegal, G. P., Baird, A., Campain, J. A., Curiel, D. T. (1997) Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor. Cancer Research 57: 1447–1451.Google ScholarPubMed
Halbert, C. L., Alexander, I. E., Wolgamot, G. M., Miller, A. D. (1995) Adeno-associated virus vectors transduce primary cells much less efficiently than immortalized cells. Journal of Virology 69: 1473–1479.CrossRefGoogle ScholarPubMed
Heise, C, Sampson-Johannes, A., Williams, A., McCormick, F., Von Hoff, D. D., Kirn, D. H. (1997) ONYX-015, an EIB attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nature Medicine 3 (6): 639–645.CrossRefGoogle Scholar
Hurford, R., Dranoff, G., Mulligan, R., Tepper, R. (1995) Gene therapy of metastatic cancer by in vivo retroviral gene targeting. Nature Genetics 10: 430–435.CrossRefGoogle ScholarPubMed
James, R. F., Edwards, S., Hui, K. M., Bassett, P. D., Grosveld, F. (1991) The effect of class II gene transfection on the tumorigenicity of the H-2K negative mouse leukemia cell line. Immunology 72: 213–218.Google Scholar
Kasid, A., Morecki, S., Aebersold, P., Cornetta, K., Culver, K., Freeman, S., Director, E., Lotze, M. T., Blaese, R. M., Anderson, W. F. et al. (1990) Human gene transfer: characterization of human tumor-infiltrating lymphocytes as vehicles of retroviral-mediated gene transfer in man. Proceedings of the National Academy of Sciences of the United States of America 87 (1): 473–477.CrossRefGoogle ScholarPubMed
Knowles, M. R., Hohneker, K. W., Zhou, Z., Olsen, J. C, Noah, T. L., Hu, P. C, Leigh, M. W., Engelhardt, J. F., Edwards, L. J., Jones, K. R. et al. (1995) A controlled study of adenoviral vector mediated gene transfer in the nasal epithelium of patients with cystic fibrosis. New England Journal of Medicine 333: 823–831.CrossRefGoogle ScholarPubMed
Knox, R. J., Friedlos, F., Jarman, M., Roberts, J. J. (1988) A new cytotoxic, DNA interstrand cross-linking agent, 5-(aziridan-l-yl)-4-hydroxylamino-2-nitrobenzamide, is formed from 5-(aziridin-l-yl-2,4-dinitrobenzamide) (CB 1954) by a nitroreductase enzyme in Walker carcinoma lines. Biochemical Pharmacology 37: 4661–669.CrossRefGoogle Scholar
Kochanek, S., Clemens, P. R., Mitani, K., Chen, H. H., Chan, S., Caskey, C. T. (1996) A new adenoviral vector: Replacement of all viral coding sequences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase. Proceedings of the National Academy of Sciences of the United States of America 93 (12): 5731–5736.CrossRefGoogle ScholarPubMed
Kucharczuk, J. C., Randazzo, B., Chang, M. Y., Amin, K. M., Elshami, A. A., Sterman, D. H., Rizk, N. P., Molnar-Kimber, K. L., Brown, S. M., MacLean, A. R., Litzky, J. A., Fraser, N. W., Albelda, S. M., Kaiser, L. R. (1997) Use of a ‘replication-restricted’ herpes virus to treat experimental human malignant mesothelioma. Cancer Research 57 (3): 466–471.Google ScholarPubMed
Kun, L. E., Gajjar, A., Muhlbauer, M., Heideman, R. L., Sanford, R., Brenner, M., Walter, A., Langston, J., Jenkins, J., Facchini, S. (1995) Stereotactic injection of herpes simplex thymidine kinase vector producer cells (PA317- GlTklSvNa 7) and intravenous ganciclovir for the treatment of progressive or recurrent primary supratentorial pediatric malignant brain tumors. Human Gene Therapy 6 (9): 1231–1255.CrossRefGoogle ScholarPubMed
Leiden, J. (1995) Gene therapy – promises, pitfalls and prognosis. New England Journal of Medicine 333: 871.CrossRefGoogle ScholarPubMed
Lejeune, F., Lienard, D., Eggermont, A., Schrafford Koops, H., Rosenkaimer, F., Gerain, J., Klaase, J., Kroon, B., Vanderveken, J., Schmitz, P. (1994) Rationale for using TNF alpha and chemotherapy in regional treatment of melanoma. Journal of Cellular Biochemistry 56: 52–61.CrossRefGoogle ScholarPubMed
Liu, T. J., Zhang, W. W., Taylor, D. L., Roth, J. A., Goepfert, H., dayman, G. L. (1994) Growth suppression of human head and neck cancer cells by the introduction of a wildtype p53 gene via a recombinant adenovirus. Cancer Research 54 (14): 3662–3667.Google ScholarPubMed
Markowitz, D., Goff, S., Bank, A. (1988) Construction and use of a safe and efficient amphotropic packaging cell line. Virology 167: 400–406.CrossRefGoogle ScholarPubMed
McKie, E. A., MacLean, A. R., Lewis, A. D., Cruickshank, G., Rampling, R., Barnett, S. C, Kennedy, P. G., Brown, S. M. (1996) Selective in vitro replication of herpes simplex virus type I (HSV-1) ICP34.5 null mutants in primary human CNS tumours – evaluation of a potentially effective clinical therapy. British Journal of Cancer 74 (5): 745–752.CrossRefGoogle ScholarPubMed
McLachlan, G., Ho, L. P., Davidson-Smith, H., Samways, J., Davidson, H., Stevenson, B. J., Carothers, A. D., Alton, E. W., Middleton, P. G., Smith, S. N., Kallmeyer, G., Michaelis, U., Seeber, S., Naujoks, K., Greening, A. P., Innes, J. A., Dorin, J. R., Porteous, D. J. (1996) Laboratory and clinical studies in support of cystic fibrosis gene therapy using pCMV-CFTR-DOTAP. Gene Therapy 3 (12): 1113–1123.Google ScholarPubMed
Melton, D., Konecki, D., Brennand, J., Caskey, C. (1984) Structure, expression and mutation of the hypoxanthine phosphoribosyl transferase gene. Proceedings of the National Academy of Sciences of the United States of America 81: 2147–2151.CrossRefGoogle Scholar
Moolten, F. (1986) Tumour chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Research 46: 5276–5281.Google ScholarPubMed
O'Malley, B. W. Jr., Sewell, D. A., Li, D., Kosai, K., Chen, S. H., Woo, S. L., Duan, I. (1997) The role of interleukin-2 in combination adenovirus gene therapy for head and neck cancer. Molecular Endocrinology 11 (6): 667–673.CrossRefGoogle ScholarPubMed
Orkin, S. H., Daddona, P. F., Shewach, D. S., Markham, A. F., Bruns, G. A., Goff, S. C, Kelley, W. N. (1983) Molecular cloning of human adenosine deaminase gene sequences. Journal of Biological Chemistry 258: 12753–12756.CrossRefGoogle ScholarPubMed
Pardoll, D. M. (1993) Cancer vaccines. Immunology Today 14: 310–316.CrossRefGoogle ScholarPubMed
Pirollo, K. F., Hao, Z., Rait, A., Jang, Y. J., Fee, W. E. Jr., Ryan, P., Chiang, Y., Chang, F. H. (1997) p53 mediated sensitization of squamous cell carcinoma of the head and neck to radiotherapy. Oncogene 14 (14): 1735–1746.CrossRefGoogle ScholarPubMed
Plautz, G. E., Yung, Z. Y., Wu, B. Y., Guo, X., Huang, T., Nabel, G. J. (1993) Immunotherapy of malignancy by in vivo gene transfer into tumors. Proceedings of the National Academy of Sciences of the United States of America 90: 4645–649.CrossRefGoogle ScholarPubMed
Riordan, J. R., Rommens, J. M., Kerem, B., Alon, N., Rozmahel, R., Grzelezak, Z., Zielenski, J., Lok, S., Plavsic, N., Chou, J. L. et al. (1989) Identification of the cystic fibrosis gene: cloning and characterization of the complementary DNA. Science 245: 1066–1073.Google ScholarPubMed
Rommens, J. M., Jannuzzi, M. C, Kerem, B., Drumm, M. L., Melmer, G., Dean, M., Rozmahel, R., Cole, J. I., Kennedy, D., Hidaka, N., et al. (1989) Identification of the cystic fibrosis gene – chromosome walking and jumping. Science 245: 1059–1065.CrossRefGoogle ScholarPubMed
Roth, J. A., Nguyen, D., Lawrence, D. D., Kemp, B. L., Carrasco, C. H., Ferson, D. Z., Hong, W. K., Komaki, R., Lee, J. J., Nesbitt, J. C, Pisters, K. M., Putnam, J. B., Schea, R., Shin, D. M, Walsh, G. L., Dolormente, M. M., Han, C. I., Martin, F. D., Yen, N., Xu, K., Stephens, L. C., McDonnell, T. J., Mukhopadhyay, T., Cai, D. (1996) Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nature Medicine 2 (9): 985–991.CrossRefGoogle ScholarPubMed
Sivanandham, M., Scoggin, S. D., Sperry, R. G., Wallack, M. K. (1992) Prospects for gene therapy and lymphokine therapy for metastatic melanoma. Annals of Plastic Surgery 28: 114–118.CrossRefGoogle ScholarPubMed
Takahashi, T., Carbone, D., Takahashi, T., Nau, M. M., Hida, T., Linnoila, I., Ueda, R., Minna, J. D. (1992) Wild-type but not mutant p53 suppresses the growth of human lung cancer cells bearing multiple genetic lesions. Cancer Research 52 (8): 2340–2343.Google Scholar
Tursz, T., Cesne, A. L., Baldeyrou, P., Gautier, E., Opolon, P., Schatz, G., Pavirani, A., Courtney, M., Lamy, D., Ragot, T., Saulnier, P., Andremont, A., Monier, R., Perricaudet, M., Le Chevalier, T. (1996) Phase I study of a recombinant adenovirus-mediated gene transfer in lung cancer patients. Journal of the National Cancer Institute 88 (24): 1857–1863.CrossRefGoogle ScholarPubMed
Verma, I. (1994) Gene Therapy: hopes, hypes and hurdles. Molecular Medicine 1: 3.CrossRefGoogle ScholarPubMed