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Primary non-Hodgkin's lymphoma of the larynx

Published online by Cambridge University Press:  29 June 2007

Shingo Kato*
Affiliation:
Department of Radiotherapy, Saitama Cancer Center, Saitama, Japan.
Mizuyoshi Sakura
Affiliation:
Department of Radiotherapy, Saitama Cancer Center, Saitama, Japan.
Shoji Takooda
Affiliation:
Department of Clinics of Otolaryngology, Saitama Cancer Center, Saitama, Japan.
Masaharu Sakurai
Affiliation:
Department of Hematology, Saitama Cancer Center, Saitama, Japan.
Toshiyuki Izumo
Affiliation:
Department of Clinical Pathology, Saitama Cancer Center, Saitama, Japan.
*
Address for correspondence: Shingo Kato, M.D., Department of Radiotherapy, Saitama Cancer Center, 818 Komuro Ina-machi Kitaadachi-gun Saitama-ken 362, Japan. Fax: +81-48-723-5197

Abstract

Three cases of primary non-Hodgkin's lymphoma of the larynx are described. Histologically, two tumours belonged to the category of low grade B-cell lymphomas of the small cell type (extranodal marginal zone B-cell lymphoma and lymphoplasmacytoid lymphoma), and the third was classified as a peripheral T-cell lymphoma of unspecified type. The clinical stage was IE in two cases, and IV in another case. In two cases, complete remission was obtained with radical radiotherapy. But in the other case, which was histologically lymphoplasmacytoid lymphoma, the response to radiotherapy was poor, and surgery was required. There was no relapse subsequent to treatment. Primary non-Hodgkin's lymphoma of the larynx is rare. Several reported cases have clinical features similar to those of MALT-type lymphomas arising in other extranodal sites. Although most of the reported cases have been cured with radiotherapy, in some cases dissemination to other extranodal sites may occur. Therefore careful periodic evaluation is imperative.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1997

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