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Post-irradiation sudden deafness

Published online by Cambridge University Press:  29 June 2007

Yi-Ho Young  and
Pei-Jen Lou
Yi-Ho Young*
Affiliation:
Department of Otolaryngology, National Taiwan University, Taipei, Taiwan.
Pei-Jen Lou
Affiliation:
Department of Otolaryngology, National Taiwan University, Taipei, Taiwan.
*
Address for correspondence: Yi-Ho Young, M.D., Department of Otolaryngology, National Taiwan University Hospital, 1 Chang-te St., Taipei, Taiwan. Fax: (886)-2-23410905 e-mail: [email protected]
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Abstract

As in radiation-induced cancer, post-irradiation sudden deafness (PISD) is defined as sudden onset deafness in patients post-irradiation. Fifteen nasopharyngeal carcinoma (NPC) patients with PISD were enrolled in this study. The mean interval from the completion of irradiation to the occurrence of PISD was 12 years. Seven had total deafness, seven had profound hearing loss, and one had moderate hearing loss. Nine out of 15 (60 per cent) patients experienced hearing recovery within three months after treatment. In conclusion, PISD is a late complication in NPC patients post-irradiation. The causative mechanism is theorized as vascular insufficiency.

Keywords

Deafness, suddenNasopharyngeal neoplasmsRadiation effects
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 113 , Issue 9 , September 1999 , pp. 815 - 817
Copyright
Copyright © JLO (1984) Limited 1999

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