Hostname: page-component-586b7cd67f-dlnhk Total loading time: 0 Render date: 2024-11-26T02:05:52.546Z Has data issue: false hasContentIssue false
  • English
  • Français

Parapharyngeal malignant ectomesenchymoma: Combined malignant fibrous histiocytoma and primitive neuroectodermal tumour with neuroglial differentiation

Published online by Cambridge University Press:  29 June 2007

V. Kasantikul ,
S. Shuangshoti ,
A. Cutchavaree  and
P. Bunyaphiphat
V. Kasantikul
Affiliation:
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Recipients of funds from the Anandhamahidol Foundation, Medical Section, Bangkok.
S. Shuangshoti*
Affiliation:
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Recipients of funds from the Anandhamahidol Foundation, Medical Section, Bangkok.
A. Cutchavaree
Affiliation:
Department of Ear, Nose and Throat, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
P. Bunyaphiphat
Affiliation:
Department of Ear, Nose and Throat, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
*
Professor Samruay Shuangshoti, M.D., Department of Pathology, Chulalongkorn Hospital, Bangkok 10500, Thailand.
Get access Rights & Permissions [Opens in a new window]

Abstract

A parapharyngeal ectomesenchymoma consisting of mixed malignant fibrous histiocytoma and primitive neuroectodermal tumour with neuroglial differentiation occurred in a 36-year-old woman. Immunohistochemical and electron microscopic studies verified the combined mesenchymal and neuroectodermal components within the tumour. Only 9 similar cases, including the present one, are on record. The patients ranged in age from 6 months to 49 years, with an average age of 18 years. The male: female ratio was 4:5. The tumour location was widespread. All reported ectomesenchymomas were histopathologically malignant. Recurrence and/or metastasis was/were common. The neural crest has been suggested as the origin of the ectomesenchymomas.

Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 101 , Issue 5 , May 1987 , pp. 508 - 515
Copyright
Copyright © JLO (1984) Limited 1987

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Churg, A. M. and Kahn, L. B. (1980) Myofibroblasts and related cells in malignant fibrous and fibro-histiocytic tumours. Human Pathology, 8: 205–218.CrossRefGoogle Scholar
Enzinger, F. M. and Weiss, S. W. (1983) Soft Tissue Tumours. C. V. Mosby Co., St. Louis, pp. 166–198, 370 & 371.Google Scholar
Karcioglu, Z., Someren, A. and Mathes, S. J. (1977) Ectomesenchymoma:- A malignant tumour of migratory neural crest (ectomesenchyme) remnants showing ganglionic, Schwannian, melanocytic and rhabdomyoblastic differentiation. Cancer, 39: 2486–2496.3.0.CO;2-E>CrossRefGoogle ScholarPubMed
Meister, P. and Nathrath, W. (1980) Immu-nohistochemical markers of histiocytic tumours. Human Pathology, 11: 300–301.CrossRefGoogle Scholar
Naka, A., Matsumoto, S., Shirai, T. and Itoh, T. (1975) Ganglioneuroblastoma associated with malignant mesenchymoma. Cancer, 36: 1050–1056.3.0.CO;2-C>CrossRefGoogle ScholarPubMed
Seemayer, T. A., Thelmo, W. L., Bolande, R. P. and Wiglesworth, F. W. (1975) Peripheral neuroec-todermal tumours. Perspective Pediatric Pathology, 2: 151–172.Google Scholar
Shuangshoti, S. (1986) Primitive neuroectodermal (neuroepithelial) tumour of soft tissues of neck of a child: Demonstration of neuronal and neuroglial differentiation. Histopathology, 10: 651–658.CrossRefGoogle ScholarPubMed
Shuangshoti, S. and Cutchavaree, A. (1980) Para-pharyngeal neoplasm of mixed mesenchymal and neuroepithelial origin. Archives of Otolaryngology, 106: 361–364.CrossRefGoogle Scholar
Shuangshoti, S. and O'Charoen, S. (1983) Cerebellar neoplasms of mixed mesenchymal and neuroepithelial origin: Case report. Journal of Neu-rosurgery, 59: 337–343.Google ScholarPubMed
Shuangshoti, S., Kasantikul, V., Suwangool, P. and Chittmittrapap, S. (1984) Malignant neoplasm of mixed mesenchymal and neuroepithelial origin (ectomesenchymoma) of thigh. Journal of Surgical Oncology, 27: 208–213.CrossRefGoogle ScholarPubMed
Sirikulchayanonta, V. and Wongwaisayawan, S. (1984) Malignant ectomesenchymoma (neoplasm of mixed mesenchymal and neuroepithelial origin) of wrist joint. Journal of Medical Association of Thailand, 67: 356–361.Google ScholarPubMed
Sternberger, L. A., Hardy, P. H., Cuculis, J. J. and Mayer, H. G. (1970) The unlabelled antibody enzyme method of immunohistochemistry. Journal of Histochemistry and Cytochemistry, 18: 315–333.CrossRefGoogle ScholarPubMed
Weston, T. A. (1970) The migration and differentiation of neural crest cells. In Advances in Morphogenesis (Abercrombie, H., Brachet, J. and King, T. J. eds). Academic Press, New York, pp. 41–114.Google Scholar