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Oncogenic osteomalacia: case report and review of head and neck associated tumours

Published online by Cambridge University Press:  29 June 2007

X. Gonzalez-Compta ,
M. Mañós-Pujol ,
M. Foglia-Fernandez ,
E. Peral ,
E. Condom ,
T. Claveguera  and
M. Dicenta-Sousa
X. Gonzalez-Compta*
Affiliation:
Department of Oto-rhino-laryngology, Ciutat Sanitària Universitària de Bellvitge, Barcelona, Spain.
M. Mañós-Pujol
Affiliation:
Department of Oto-rhino-laryngology, Ciutat Sanitària Universitària de Bellvitge, Barcelona, Spain.
M. Foglia-Fernandez
Affiliation:
Department of Oto-rhino-laryngology, Ciutat Sanitària Universitària de Bellvitge, Barcelona, Spain.
E. Peral
Affiliation:
Department of Neurology, Ciutal Sanitària Universitària de Bellvitge, Barcelona, Spain.
E. Condom
Affiliation:
Department of Pathology, Ciutal Sanitària Universitària de Bellvitge, Barcelona, Spain.
T. Claveguera
Affiliation:
Department of Rheurmatology, Ciutal Sanitària Universitària de Bellvitge, Barcelona, Spain.
M. Dicenta-Sousa
Affiliation:
Department of Oto-rhino-laryngology, Ciutat Sanitària Universitària de Bellvitge, Barcelona, Spain.
*
Address for correspondence: Xavier Gonzalez-Compta, C/Montserrat de Casanovas, 124, 2°4a Barcelona - 08032, Spain. Fax: (3) 207 50 63
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Abstract

Oncogenic osteomalacia is an uncommon syndrome characterized by mineral metabolism abnormalities that disappear after the resection of an associated tumour. Head and neck is the second most frequent location of these tumours. We describe a case with an ethmoido-frontal phosphaturic mesenchymal tumour and review oncogenic osteomalacia-associated tumours. Among 21 cases found, 57 per cent affected the sinonasal area and 20 per cent the mandible. The diagnosis of the tumour lasted a mean of 4.7 years from the onset of osteomalacia, and most of them showed a significant vascular component. An aggressive surgical approach is recommended.

Keywords

Head and neck neoplasmsOsteomalaciaHypophosphataemia
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 112 , Issue 4 , April 1998 , pp. 389 - 392
Copyright
Copyright © JLO (1984) Limited 1998

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