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Malignant peripheral nerve sheath tumours of the infraorbital nerve: case report and literature review

Published online by Cambridge University Press:  20 May 2008

I Beegun ,
I D Bottrill  and
K Hollowood
I Beegun
Affiliation:
Department of Otolaryngology, Head & Neck Surgery, John Radcliffe Hospital, Oxford, UK
I D Bottrill*
Affiliation:
Department of Otolaryngology, Head & Neck Surgery, John Radcliffe Hospital, Oxford, UK
K Hollowood
Affiliation:
Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK
*
Address for correspondence: Mr I Bottrill, Departments of Otolaryngology, Head & Neck Surgery, John Radcliffe Hospital, Oxford OX2 6HE, UK. E-mail: [email protected]
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Abstract

Objective:

We report a case of malignant peripheral nerve sheath tumour seen in our department.

Method:

We present case reports and a review of the world literature concerning malignant peripheral nerve sheath tumour.

Results:

A 38-year-old Caucasian woman was diagnosed with malignant peripheral nerve sheath tumour of the infraorbital nerve. She underwent a wide enbloc resection followed by a course of radiotherapy. A five-year post-operative magnetic resonance imaging scan revealed no evidence of recurrence.

Conclusion:

Malignant peripheral nerve sheath tumours are rare in the head and neck. An awareness of their occurrence is important for early diagnosis. Management involves: accurate histological diagnosis; radiological imaging to define tumour extent and plan resection; wide surgical excision with histologically negative margins; reconstruction of the tissue defect; and post-operative radiotherapy.

Keywords

Malignant Peripheral Nerve Sheath TumourSarcomaHead and Neck NeoplasmsTrigeminal Nerve
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 123 , Issue 4 , April 2009 , pp. 466 - 470
Copyright
Copyright © JLO (1984) Limited 2008

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